Anthera Pharmaceuticals Inc., of Hayward, Calif., added Brian R. Mueller to its board and named him chairman of the audit committee.

Ariad Pharmaceuticals Inc., of Cambridge, Mass., named Timothy Maines vice president, quality, Yan Moore vice president, medical affairs, and Piet A.M. Vervaet vice president, drug safety and pharmacovigilance.

Cara Therapeutics Inc., of Shelton, Conn., appointed Robert Medve chief medical officer.

Cipher Pharmaceuticals Inc., of Mississauga, Ontario, named Shawn Patrick O'Brien CEO.

Editas Medicine, of Cambridge, Mass., named Katrine S. Bosley CEO.

Esperion Therapeutics Inc., of Plymouth, Mich., added Gilbert S. Omenn to its board.

Nuevolution A/S, of Copenhagen, named Peter Hirth corporate advisor.

Pernix Therapeutics Holdings Inc., of Morristown, N.J., appointed Sanjay Patel chief financial officer.

Senesco Technologies Inc., of Bridgewater, N.J., named Ronald A. Martell CEO. Vaughn V. Smider, acting CEO, will remain chief scientific officer and a member of the board.

Shire plc, of Dublin, appointed Reza Haque therapeutic area head for ophthalmology. He will be based in Lexington, Mass.

Summit plc , of Oxford, UK, appointed Erik Ostrowski chief financial officer. He will be based in Cambridge, Mass.

Tapimmune Inc., of Seattle, appointed Keith Knutson chairman of its scientific advisory board.

Tetraphase Pharmaceuticals Inc., of Watertown, Mass., appointed Jeffrey A. Chodakewitz to its board.

Tobira Therapeutics Inc., of South San Francisco, added Jeffrey H. Cooper, Craig S. Gibbs, Gwen A. Melincoff and Graeme J. Moyle to its board.

Tocagen Inc., of San Diego, appointed Jamey Skillings senior vice president and chief medical officer.

Tonix Pharmaceuticals Holding Corp., of New York, appointed Ronald R. Notvest senior vice president, commercial planning and development.

Tris Pharma Inc., of Monmouth Junction, N.J., appointed Sally A. Berry chief medical officer and Norma Cappetti vice president of regulatory affairs.

Versartis Inc., of Menlo Park, Calif., named Bert Bakker senior vice president, medical affairs.

Virobay Inc., of Menlo Park, Calif., named James Welch chief financial officer.

Voyager Therapeutics Inc., of Cambridge, Mass., named Robert G. Pietrusko senior vice president of regulatory affairs.

Xbiotech Inc., of Austin, Texas, named Gary Gonzales vice president of clinical operations.

Zosano Pharma Inc., of Fremont, Calif., added Troy Wilson to its board.