Roseanne Varner has been named president/CEO of Aspire Medical (Sunnyvale, California). Varner will also join the board of directors. Previously, Varner served as president/CEO of Atherotech. Aspire is a privately held company that makes minimally invasive surgical devices to treat obstructive sleep apnea.

• diaDexus (South San Francisco) reported two executive appointments. David Foster has been named CFO and executive VP, and Dino Alfano has been appointed executive VP of sales and marketing. Most recently, Foster served as CFO of Argonaut Technologies and Alfano was president of Iris Diagnostics. DiaDexus is a privately held biotech company.

• E-Z-EM (Lake Success, New York) reported that Dennis Curtin, VP/CFO, has resigned to pursue other opportunities. Joseph Cacchioli, currently the company's VP/Controller, will serve as acting CFO. E-Z-EM makes contrast agents for gastrointestinal radiology.

James Brenner was named chief marketing officer of LCA-Vision (Cincinnati). Most recently, he served three years as VP of marketing of Nautilus. LCA-Vision is a provider of laser vision correction services under the LasikPlus brand.

Stephen Hoffman, PhD, MD, has joined Skyline Ventures (Palo Alto, California) as managing director and will open a satellite office in Boston for Skyline. Hoffman was previously employed by TVM Capital. The firm also announced that Stephen J. Sullivan, MD, and David G. Lowe, PhD, have been promoted to managing director. Sullivan joined the firm in 2000 and Lowe joined in 2002; both were previously Partners in the firm. Skyline Ventures is a venture capital firm that focuses on medical devices and life sciences.

Richard Krzyzek has been named VP of research for the biotechnology division of Techne Corporation (Minneapolis). Krzyzek joined the R&D Systems, a subsidiary of Techne in 1992. Techne has two operating subsidiaries: Research and Diagnostic Systems (Minneapolis), and R&D Systems Europe (R&D Europe; Abingdon, England). R&D Systems makes biological products.

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