A.P. Pharma Inc., of Redwood City, Calif., appointed Anastassios Retzios vice president of clinical development.

Aastrom Biosciences Inc., of Ann Arbor, Mich., elected Stephen Sudovar chairman.

ACE BioSciences A/S, of Odense, Denmark, appointed Roberto Machuca operations manager.

Aerovance Inc., of Berkeley, Calif., elected Mark Perry executive chairman and appointed Douglas Williams to the board.

Anadys Pharmaceuticals Inc., of San Diego, appointed Lawrence Fritz president and CEO and a board member.

Anika Therapeutics Inc., of Woburn, Mass., appointed Constance Garrison as vice president of regulatory and clinical affairs.

Bayhill Therapeutics Inc., of Palo Alto, Calif., named Robert King vice president of manufacturing.

Diffusion Pharmaceuticals LLC, of Charlottesville, Va., appointed Matthew Hanzmon vice president of business development.

Digene Corp., of Gaithersburg, Md., named Daryl Faulkner president and CEO and a board member.

Gene Express Inc., of Toronto, appointed Colette Saccamanno director of business development.

GeneNews Ltd., of Toronto, appointed Roman Zastawny vice president of biomarker development.

KAI Pharmaceuticals Inc., of South San Francisco, appointed Dirk Mendel vice president of pharmacology and preclinical pharmacokinetics and pharmacodynamics.

Keryx Biopharmaceuticals Inc., of New York, appointed Wyche Fowler to its board.

Koronis Pharmaceuticals Inc., of Seattle, named Stephen Becker chief medical officer.

Kosan Biosciences Inc., of Hayward, Calif., named Robert De Jager senior vice president of clinical development and chief medical officer.

Lentigen Corp., of Baltimore, appointed Adam Sachs president of commercial operations.

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