MediQuest Therapeutics Inc., of Bothell, Wash., was issued U.S. Patent No. 6,963,010, titled "Hydrophobic Polyamine Analogs and Methods for Their Use," covering a class of compounds that have immunomodulatory and antiproliferative properties.

Nanogen Inc., of San Diego, received U.S. Patent No. 6,962,991, titled "Process for the Synthesis of Pyrazolopyrimidines," relating to a process of the synthesis of pyrazolopyrimidine nucleoside phosphoramidites. Nanogen's subsidiary, Epoch Biosciences Inc., of Bothell, Wash., recently received U.S. Patent No. 6,972,339, titled "Compounds and Methods for Fluorescent Labeling," and Patent No. 6,972, 328, titled "Non-aggregating Non-quenching Oligomers Comprising Nucleotide Analogs, Method of Synthesis and Use Thereof." Both relate to technologies for genetic analyses.

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