Biotech Co.*
(Country;
Symbol)

Biotech Co.*
(Country;
Symbol)

Product

Terms/Details (Date)


BioInvent International
AB
(Sweden; SSE:BINV)

CellControl Biomedical Laboratories AG* (Germany)

ACA-125 antibody

Agreement is for BioInvent to com- plete large-scale cGMP manufacturing of CellControl's ACA-125 antibody for Phase III trials, as well as to provide regulatory support (4/12)

BioReliance Corp. (BREL)

Celltech Group plc (UK; NYSE:CLL; LSE:CCH)

Clinical-grade antibody fragment-based drugs

BioReliance will manufacture and supply the drugs to Celltech; the contract provides for BioReliance to support three product candidates in 2002, plus a minimum of two additional candidates in earlier stages of development during 2003 (3/26)

Cepheid Inc. (CPHD)

Bucher Biotec AG* (Switzerland)

Smart Cycler system, accessories and disposable reaction tubes

Bucher will provide marketing, sales and service support for the Smart Cycler line in Switzerland (5/22)

Immunex Corp. (IMNX)

Genentech Inc. (NYSE:DNA)

Enbrel

Manufacturing agreement in which Genentech will produce Enbrel at its facility in South San Francisco (4/15)

Lipid Sciences Inc. (LIPD)

Progen Industries Ltd. (Australia; PGLAF)

Human plasma samples taken from healthy volunteers with elevated plasma cholesterol

The manufacturing contract is worth more than $267,000; Progen is responsible for manufacturing and clinical support for Lipid's Phase I trial (4/11)

Zycos Inc.*

Pharmexa A/S (Denmark)

A therapeutic DNA breast cancer vaccine in Zyco's Gencap system

Zycos will formulate Pharmexa's therapeutic DNA breast cancer vaccine in Zycos' Gencap system; Pharmexa intends to use the Gencap technology to deliver its AutoVac HER-2 DNA vaccine for a Phase II study; Pharmexa will pay Zycos for formulation, manufacturing and scale-up; it also will make potential milestone and royalty payments (5/15)


Notes:

# The information in the chart does not cover agricultural agreements.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

ND = Not disclosed, reported and/or available.

LSE = London Stock Exchange; NYSE = New York Stock Exchange; SSE = Stockholm Stock Exchange

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