Genome Therapeutics Corp., of Waltham, Mass., promoted Lynn Doucette-Stamm to vice president and general manager, GTC Sequencing Business, and Andrew DePristo to vice president, BioInformatics and Emerging Technologies.

ImmunoGen Inc., of Cambridge, Mass., named to its board of directors Mark Skaletsky, CEO and president of GelTex Pharmaceuticals Inc.

Locus Discovery Inc., of Princeton, N.J., named Nicholas Landekic president and CEO.

Medarex Inc., of Princeton, N.J., named W. Bradford Middlekauff vice president, general counsel and secretary.

OraPharma Inc., of Warminster, Pa., appointed Joseph Truitt national director of sales, and Russell Secter executive director of marketing.

Orquest Inc., of Mountain View, Calif., named Gregory Casciaro chief executive officer and president.

Photogen Technologies Inc., of Knoxville, Tenn., named Taffy Williams president and CEO.