A.M. Pappas & Associates, of Durham, N.C., named Chris Offen senior vice president and managing director of its Atlanta office.

Abgenix Inc., of Fremont, Calif., named Patrick Murphy vice president, manufacturing.

Aerogen Inc., of Sunnyvale, Calif., elected to its board of directors Phyllis Gardner, senior associate dean for education and student affairs and associate professor of molecular pharmacology and medicine at Stanford University School of Medicine. In addition, Deborah Karlson was promoted to chief financial officer.

Annovis Inc., of Aston, Pa., named Bruce Galton president and chief operating officer.

Aphton Corp., of Miami, named to its board of directors Georges Hibon, former chairman and CEO of Pasteur Merieux N.A.

Arius Research Inc., of Toronto, appointed Christian Frayssignes president and chief operating officer.

Aviron, of Mountain View, Calif., promoted Edward Arcuri to senior vice president, operations.

Collateral Therapeutics Inc., of San Diego, named John Warner vice president, technology.

Cubist Pharmaceuticals Inc., of Cambridge, Mass., appointed Jennifer LaVin senior director of communications.

CuraGen Corp., of New Haven, Conn., named Hovan Asdourian senior vice president of business development and head of its pharmaceutical business development team.

EluSys Therapeutics Inc., of Pine Brook, N.J., appointed Debra Brennan director of administration, Leslie Casey director of laboratory operations, Cynthia Pletcher director of special projects, and James Porter director of product development.

Endovasc Ltd. Inc., of Montgomery, Texas, appointed Diane Dottavio director of research and development.

Entropin Inc., of Indio, Calif., named to its board of directors Joseph Ianell, president and CEO of Renaissance Pharmaceuticals Inc., and Wilson Benjamin, president and CEO of Al Fawaris Co.

Epimmune Inc., of San Diego, named to its board of directors John McKearn, vice president, discovery research at Pharmacia Corp.

Genaissance Pharmaceuticals Inc., of New Haven, Conn., named Paul Oestreicher vice president, public affairs.

Genentech Inc., of South San Francisco, appointed Myrtle Potter executive vice president of commercial operations and chief operating officer; Roy Hardiman vice president, corporate law; and Andrew Scherer vice president, engineering and facilities.