Published September 1 (EPO); August 26 (WO)
Arkansas, Univ. of WO 99/42120
Cancer serine protease
Little Rock, Ark.
An extracellular serine protease overexpressed in breast and ovarian carcinomas, encoding gene sequences.
BASF WO 99/42591
Genes for enzymes in the biotin synthesis pathway; for transforming microorganisms and producing biotin.
Biochem Vaccins WO 99/42588
Group B streptococcal antigens, encoding gene sequences, production methods; for diagnostics and vaccines.
Biostar WO 99/42573
Myostatin peptide immunogens, immunoconjugates, and multimers; for modulating myostatin activity.
Biotech. Res. Inst. EPO 939 120
Expression cassette exchange
Marker-free repetitive DNA expression cassette exchange using FLP recombinase-mediated methods.
Bristol-Myers Squibb WO 99/42075
T cell humoral responses
Chimeric and humanized CD40 antibodies that block the gp39-CD40 interaction; for modulating T cell humoral responses.
Bromley, P. WO 99/42137
Stress promoter gene therapy
Controlling therapeutic gene expression using heat shock or stress promoters; for gene therapy protocols.
California, Univ. of WO 99/41974
Modulating seed mass
Producing transgenic plants having the ADC gene linked to a plant promoter; for modulating seed mass.
California, Univ. of WO 99/42478
Antigenic outer membrane protein preparations from pathogenic Leptospira, antibodies; for vaccines.
California, Univ. of WO 99/42487
Concentrating and analyzing disease-related conformations of prion protein complexes; for diagnostics.
City of Hope WO 99/42619
Cardiovascular disease screen
Detection of serotonin transport gene; for cardiovascular disease screens and developing therapeutics.
Cold Spr. Harbor Labs WO 99/42578
Cell cycle control
Cold Spr. Harbor, N.Y.
Polypeptides capable of bypassing a cell cycle checkpoint; for inducing cell growth.
Connaught Labs WO 99/42130
North York, Ont.
Multivalent immunogenic bacterial oligosaccharide glycoconjugates; for meningitis vaccines.
Corixa WO 99/42076 & 42118
Mycoplasm tuberculosis immunogenic proteins, encoding gene sequences; for tuberculosis diagnosis and vaccines.
Cornell Univ. WO 99/42594
Chitinolytic enzymes, encoding genes; for transforming plants and seeds to control fungi and insects.
Cotton WO 99/41975
Transformation of metabolically slowed apical meristems using plasmids or Agrobacterium; for transgenic plants.
Dade Behring WO 99/42615, 426166 & 42618
Detecting nucleic acids
Quantitative determination of single-stranded nucleic acids using probes and signals generated by probe binding.
Dana-Farber Cancer Inst. WO 99/42622
Methods for identifying mismatch repair glycosylase reactive sites; for finding mutations and polymorphisms.
Eastern Virginia Med. Sch. WO 99/42581
Sperm binding protein assay
Fully glycosylated recombinant active human zona pellucida protein; for finding peptides that bind to sperm.
Eurogene WO 99/42577
Biotin binding protein
Transmembrane protein having biotin receptor activity, various domains; for binding biotinylated molecules.
Fred Hutchinson Cancer Res. Ctr. WO 99/41984
DNA synthesis checkpoint
Interaction between the MEC1-dependent DNA synthesis checkpoint and G1 cyclin function in yeast.
French Atomic Energy Comm. WO 99/42128
HLA-G expressing tumors
Expression profiling of tumors; for selecting HLA-G positive cancers and developing anti-cancer therapeutics.
Fujisawa Pharma EPO 939 119
Membrane protein genes
Cloning membrane protein genes by isolating signal sequence-containing DNA and N-terminal protein sequencing.
Genetics Inst. WO 99/42470
Secreted proteins, encoding gene sequences, production methods; for developing diagnostics and therapeutics.
- Compiled by Chester A. Bisbee