Company

Location

Date

Amount (M)

Investors/Business Focus

Cerexus

London

7/98

ND

Cerexus was spun off from Cerebrus Ltd. to explore the use of sodium channel blockers for the treatment of stroke and other neurological disorders.

Enzacta

Salisbury

7/98

£2

Enzacta raised £2M from 3i plc to develop cancer chemotherapies using a toolkit approach of targeting agents, enzymes and clearance agents.

Hoeft Rademacher Ltd.

London

1/98

£6

Apax Partners invested £4M and Advent International invested £2M to finance the company's research on phosphoglycokines, extra-cellular messengers with effects similar to a number of peptide hormones and growth factors.

Microgenics Ltd.

Oxford

7/98

£2.5

Oxford Molecular plc provided £2.5M to develop screening systems for novel antibiotics that interfere with bacterial cell division and spore formation.

Neutec Pharma

Manchester

6/98

£7.3

Neutec raised £7.3M from 3i plc and ABN AMRO. The company was founded to exploit observations that patients who recover from hospital-acquired infections by "superbugs" produce neutralizing antibodies.

OraTol Ltd.

London

6/98

£5

OraTol was spun out of Cortecs plc; 3-year financing of £5M was provided by Atlas Venture, JAFCO, Kokusai Finance Co. Ltd., Saito, Ito & Partners Co. Ltd. and 1 other (unnamed) investment fund; Cortecs retains a 75% stake in OraTol. OraTol is developing treatments for allergies and autoimmune diseases based on tolerizing strategies to downregulate the immune system.

Roslin Bio-med

Edinburgh

4/98

£6

3i plc invested £6M in Roslin, which will use the money to develop the nuclear transfer technology that led to the creation of Dolly the sheep for biomedical applications, particularly xenotrans-plantation.

Synomics Ltd.

London

8/98

£4

JAFCO Co. Ltd., Biotechnology Investments Ltd., TVM Techno Venture Management and 3i plc each invested £1M in Synomics, which will develop and market bioinformatics software.