Company

Offer Date

Number Shares Unit

Price Per Share

Gross

Net

Shares Out

Diluted

Post Offer Market

Cambridge Neuro-Science Inc. (CNSI)

1/31

2.76S

11

30.4

28.1

17.8

19.2

195

Quintiles Transnational Corp. (QTRN) 1

3/6

1.42S

62.88

89

84.6

35.5

37.9

2233

Vertex Pharmaceuticals Inc. (VRTX)

3/7

3.45S

45.5

157

148.9

24.6

28.6

1117

Human Genome Sciences Inc. (HGSI)

3/14

3.19S

37

118.1

112.2

22.2

24.9

821

SangStat Medical Corp. (SANG)

3/14

2.73S

30

81.9

77.8

15.9

17

476

Protein Design Labs Inc. (PDLI) 2

3/18

2.28S

32

72.8

68.4

18

20

577

PathoGenesis Corp.(PGNS)

3/20

2.1S

27

56.7

53.1

16

19.8

433

CollaGenex Pharmaceuticals Inc. (CGPI)

4/3

1.0S

12.5

12.5

11.6

8.5

9.1

107

ArQule Inc. (ARQL) 3

4/4

1.93S

12

23.2

21.6

11.8

13.2

141

Guilford Pharmaceuticals Inc. (GLFD)

4/9

3.74S

20

74.8

70.7

18.4

21.3

369

Oxis International Inc. (OXIS) 4

5/13

9.0S

0.8

7.2

6.8

22.7

ND

18

Genetronics Biomedical Ltd. (VSE:GEB) 5

6/2

1.96S

3.12

6.1

5.8

18.7

ND

58

Emisphere Tech nologies Inc. (EMIS) 6

7/21

1.15S

19

21.9

20.8

10.7

14.8

203

Zonagen Inc. (ZONA)

7/22

2.59S

30

77.6

72.3

10.8

13.1

323

Synsorb Biotech Inc. (TSE:SYB) 7

7/23

1.15S

5.62

6.5

6.1

17.5

ND

98

ViroPharma Inc. (VPHM)

7/23

2.3S

13.75

31.6

29.4

11.5

12.2

157

Incyte Pharmaceuticals Inc. (INCY)

7/30

1.38S

67

92.3

87.7

12

14.4

801

Aviron (AVIR)

8/13

2.69S

27

72.6

69

15.9

18

430

Texas Biotechnology Corp. (TXB) 8

9/25

5.75S

5

28.8

26.7

31.8

42.2

159

Cor Therapeutics Inc. (CORR)

10/7

3.34S

19

63.4

58.9

23.5

27.8

446

Coulter Pharma ceutical Inc. (CLTR)

10/10

3.16S

15.5

49

45.9

13.5

15.1

210

Digene Corp. (DIGE)

10/15

2.25S

10

22.5

20.8

13.9

18.3

139

Maxim Pharma ceuticals Inc. (MMP) 9

10/21

2.5S

15.25

38.1

35

9.2

13.9

140

Cell Therapeutics Inc. (CTIC)

10/22

2.3S

16

36.8

34.3

15.4

16.9

246

Inhale Therapeutic Systems (INHL)

10/31

1.73S

24.88

42.9

39.8

15.5

17.7

386

Synaptic Pharma ceutical Corp. (SNAP)

10/31

2.88S

12.63

36.3

33.6

10.5

11.4

133

Genzyme Tissue Repair (GENZL)

11/3

4.0S

7.75

31

29.5

19.8

25.6

153

Sugen Inc. (SUGN)

11/7

2.0S

16

32

30.4

15.1

18.2

242

Epix Medical Inc. (EPIX)

11/11

2.47S

10

24.7

23.2

11.3

13

113

Magainin Pharma ceuticals Inc. (MAGN)

11/12

2.59S

8

20.7

19.7

22

26.5

176

Cellegy Pharma ceuticals Inc. (CLGY)

11/19

2.01S

7.5

15.1

14.3

9.6

12.8

72

Anika Therapeutics Inc. (ANIK) 10

11/25

2.88S

7

20.1

19.1

9.8

11.6

68

LifeCell Corp. (LIFC)

11/25

4.0S

4.5

18

17.1

15.1

21.6

68

Celgene Corp. (CELG)

11/26

2.2S

9

19.8

18.5

15.4

19.1

139

Vanguard Medica Group plc (LSE:VGD) 11

12/8

2.25U

20.25

45.6

41.9

31.5

ND

638


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