Published January 29 & February 5 (EPO); January 23 & 30 (WO); February 5 (GB)
American Biogenetic Sciences WO 97/02291 Soluble fibrin antibodies Copiague, N.Y. Fibrin-specific antibodies, production methods; for soluble fibrin polymer detection.
Bio Merieux EPO 755 943 Hepatitis C antibodies Marcy l'Etoile, France Peptide capable of being recognized by antibodies that bind C33 antigen of hepatitis C virus, for assays [in French].
Biocine WO 97/02348 Detoxified microbial toxins Siena, Italy Immunogenic detoxified subunit A of cholera toxin or E. coli heat labile toxin produced by site-directed mutagenesis.
Biopharm WO 97/03188 Neuropathological therapeutics Heidelberg, Germany Biologically active MP52 and/or MP121; for treating nervous system diseases.
Boehringer Mannheim WO 97/02350 Prostate-specific antigen Mannheim, Germany Recombinant unglycosylated prostate-specific antigen produced from a baculovirus expression system.
Boehringer Mannheim WO 97/03200 Modified glycoprotein production Mannheim, Germany Gene for CMP-N-acetyl-neuraminic acid hydroxylase, encoded protein; for production of modified glycoproteins.
Bristol-Myers Squibb EPO 757 099 Mutant T-cell ligands New York Mutant CTLA4 ligands for B7 antigen, soluble forms, fusion proteins, for regulating T cell-mediated immune responses.
Ctr. Oral Biol. WO 97/02730 Enamel matrix-related protein Huddinge, Sweden Gene for enamel matrix-related protein, encoded protein, antibodies; for treating dental diseases.
Centocor EPO 755 683 Gastrointestinal cancer antibody Malvern, Penn. Monoclonal antibody that specifically binds to gastrointestinal adenocarcinomas; for treatment.
Chiron WO 97/03191 & 03193-03195 Factor VIII:C analogs Emeryville, Calif. Factor VIII:C polypeptide analogs with altered biological activities; for treatment of deficiencies.
Chugai EPO 756 005 Adversins Tokyo Genes for adversins, encoded proteins, antibodies, oligos, vectors; for suppressing adversin formation.
Competitive Technol. WO 97/03199 HSV infection prevention Westport, Conn. Herpes simplex virus (HSV) glycoprotein D variants, encoding genes; for preventing and treating infection.
Copenhagen Univ. WO 97/02342 Immunotherapy antibodies Copenhagen, Denmark Antibodies and fragments from a phage display library that recognize a peptide-MHC complex; for immunotherapy.
CTRC Res. Fdn. WO 97/02279 Teleomerase transforming nucleosides San Antonio, Tex. Nucleoside analogs that convert a processive teleomerase of a cancer cell into the non-processive form of a normal cell.
Darwin Molecular WO 97/03192 Chromosome 1 Alzheimers' gene Bothell, Wash. Chromosome 1 gene and gene products; for diagnosing and treating Alzheimers' disease.
Emory Univ. WO 97/02049 Neuronal progenitor cells Atlanta, Ga. Neuronal progenitor cells that can differentiate into neurons; for treating neuronal disorders.
Gen-Probe EPO 756 010 Ribosomal RNA identification San Diego, Calif. Methods for detecting ribosomal and transfer RNA-specific nucleic acids in non-viral organisms.
Genencor Intl. WO 97/03197 Secreted proteins from bacteria Delft, Netherlands Genes for secretion factors from Gram-positive bacteria, encoded proteins; for recombinant protein production.
Genzyme WO 97/02346 Chromosome 16 genes Framingham, Mass. Human chromosome 16 genes, encoded proteins, oligos, vectors, transgenic animals containing these genes.
German Hlth. & Welfare Res. Ctr. WO 97/02355 Recombinant MVA viruses Oberschleissheim, Germany Recombinant MVA viruses used to express foreign genes; for vaccines and gene therapy.
Human Genome Sciences WO 97/02280 Breast-specific genes Rockville, Md. Human breast-specific genes, encoded proteins, antibodies; for diagnosis and treatment of cancer.
Incyte Pharma WO 97/02347 MAP kinase homolog Palo Alto, Calif. Gene for human MAP kinase homolog from the stomach, encoded protein, antibodies; for detecting inhibitors.
Inst. Genomic Res. EPO 756 006 Mycoplasma genitalium genome Rockville, Md. Nucleotide sequence of the entire genome of Mycoplasma genitalium, computer-based methods to facilitate use.
INSERM (Natl. Inst. Hlth. Med. Res.) WO 97/02344 Intracellular antigen vaccine Paris Vaccine that recognizes an intracellular antigen carried on the surface of an infectious agent; for HIV therapy.
Intrabiotics Pharma WO 97/02287 Antimicrobial parevins Sunnyvale, Calif. Compounds based on antimicrobial parevins and tachytegrins containing 15-50% basic amino acids.
Koken WO 97/02047 Gene preparation carriers Tokyo Gene preparations with desired genes integrated into them, carriers for supporting them.
Magainin Pharma WO 97/03196 Na+/H+ exchanger Plymouth Meeting, Penn. Gene for the Na+/H+ exchanger, encoded transport protein, functional characterization.
MRC (Med. Res. Coun.) WO 97/02354 p53/DP-1 complexes London Complexes of p53 with transcription factor DP-1; for assaying chemotherapeutic drugs.
Michigan, Univ. of WO 97/03087 Multiple function regulatory proteins Ann Arbor, Mich. Genes for multiple function regulatory proteins, encoded proteins, antibodies; for diagnosis and therapy.
Millennium Pharma WO 97/02048 Body weight genes Cambridge, Mass. Genes that are related to the mammalian tub gene, encoded proteins; for regulating body weight.
Mochida Pharma WO 97/02290 Fas ligand antibodies Tokyo Fas ligand antibodies; for determining ligand levels and inducing apoptosis.
Murdoch Univ. WO 97/02281 Cryptosporidium detection Murdoch, Australia Cryptosporidium-specific DNA sequences; for detecting and identifying this pathogen.
New England Biolabs EPO 757 100 Truncated thermostable polymerase Beverly, Mass. Cloning of a thermostable Bacillus stearothermophilus DNA polymerase, truncated forms, fusion proteins.
Oravax WO 97/03359 & 03360 Helicobacter ulcer therapy Cambridge, Mass. Gene for Helicobacter polypeptides, encoded proteins, antibodies; for ulcer therapy.
Orion-Yhtyma GB 2 302 874 Glandular kallikrein-1 protease Espoo, Finland Gene coding for a glandular kallikrein-1 protease from prostate, encoded protein, baculovirus expression system.
Sagami Chemical WO 97/03190 Lactose-binding protein Kanagawa, Japan Gene for human galectin-4-like protein from stomach and intestines, encoded protein; for affecting lactose binding.
S. Florida, Univ. of WO 97/03086 Early onset Alzheimer's disease Tampa, Fla. Gene for early onset Alzheimer's disease, fragments, mutants, probes, primers; for diagnosis.
Texas A&M Univ. WO 97/03198 Viral envelope targeting College Station, Tex. Hydrophobic peptide that can target a reporter gene protein to viral envelopes.
Therion Biologics WO 97/03203 Prostate-specific immune response Cambridge, Mass. Pox virus vector with gene encoding prostate-specific antigen; for vaccination and induction of immune response.
Yeda Res. & Develop. WO 97/02345 TNF modulators Rehovot, Israel Modulators that interact with the membrane-bound form of tumor necrosis factor (TNF); for function modulation.
Zeneca WO 97/03202 Sterol biosynthesis modulators London Cells with yeast acetoacetyl CoA gene operably linked to a reporter; for assaying modulators of sterol biosynthesis.