Scientists at Lawrence Livermore National Laboratory, SandiaNational Laboratories and the University of California, SanFrancisco, are testing rats to find structural changes in boneleading to osteoporosis.

Their research is the first in which sequential bone loss hasbeen documented in live animals, said John Kinney, principalinvestigator of the project at the Livermore Lab, which ismanaged by the University of California for the U.S.Department of Energy in Livermore, Calif.

The research aims to ultimately allow doctors to diagnoseosteoporosis before an injury occurs, by spotting changes thatweaken bones and make them vulnerable to the progressiveloss of density.

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