In an article published Tuesday in the July 1993 issue of theJournal of Neurochemistry, scientists at Cephalon Inc. reportedon specific small organic molecules which, in preclinical studies,promote the survival of motor neurons to the same extent orgreater than several growth factors, including basic fibroblastgrowth factor and ciliary neurotrophic factor.
The data also demonstrate that the small moleculeneurotrophic factor mimics being developed by the WestChester, Pa. company (NASDAQ:CEPH) have an effect on sensoryand other selected central nervous system neurons that havebeen found to be compromised in disease.
Cephalon is developing these molecules for a variety oftherapeutic applications in a collaboration with Kyowa HakkoKogyo Co. Ltd.
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