The AMEX Biotechnology Index closed the week on an up noteFriday, rising 1.610 to 139.280. The broader NASDAQComposite Index. was down .36 at 547.84.

Posting big gains Friday were: Biochem Pharma Inc.(NASDAQ:ECSC), up $1.63 to $13.38 a share; Ecoscience Corp.(NASDAQ:ECSC) gained $1.50 to close at $7.50; and GreenwichPharmaceuticals (NASDAQ:GRPI) up $1 to $8.

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