Researchers develop tuberous sclerosis model in tsc2-mutant zebrafish
Nov. 28, 2022
Tuberous sclerosis is a genetic disease caused by loss-of-function mutations in the TSC1 or TSC2 genes. At the neurological level, this rare disease is characterized by benign tumor growth, epilepsy, cognitive deficits and autism. Epilepsy is the main neurological trait and presents mostly as infantile spasms.