ATUX-1215 restores PP2A activity and counteracts bleomycin-induced fibrosis in vivo
June 1, 2023
Researchers from Atux Iskay LLC assessed whether reactivation of protein phosphatase 2A (PP2A) using a small-molecule PP2A activator, ATUX-1215, could counter TGF-β signaling in preclinical models of idiopathic pulmonary fibrosis (IPF).