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BioWorld - Thursday, July 17, 2025
Breaking News: Trump administration impacts continue to roil the life sciences sectorSee today's BioWorld Science
Home » NEDD8 deficiency improves response to immune checkpoint blockade in TNBC
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Cancer

NEDD8 deficiency improves response to immune checkpoint blockade in TNBC

May 22, 2024
Researchers from Uppsala University published data from a study that aimed to reveal and validate cancer vulnerabilities to immune checkpoint blockade (ICB) therapy in triple-negative breast cancer (TNBC). A human Tumor-Immune co-Culture System (TICS), which consisted of primary human lymphocytes from healthy blood donors co-cultured with human cancer cells, was optimized to perform mechanistic investigation of clinically approved ICB drugs.
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