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BioWorld - Wednesday, December 11, 2024
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» FAP inhibitor AZD-2389 improves liver fibrosis and MASH
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Gastrointestinal
FAP inhibitor AZD-2389 improves liver fibrosis and MASH
Nov. 20, 2024
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Astrazeneca plc has developed a potent oral fibroblast activation protein (FAP) inhibitor, AZD-2389, that avoids the cleavage of FGF21 and α2-AP. AZD-2389 was tested in cynomolgus monkeys with diet-induced MASH.
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