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BioWorld - Sunday, May 18, 2025
Breaking News: 100 days of uncertaintySee today's BioWorld Science
Home » Humanwell Healthcare discovers new IRAK-4 degradation inducers
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Dermatologic

Humanwell Healthcare discovers new IRAK-4 degradation inducers

Feb. 28, 2025
Humanwell Healthcare (Group) Co. Ltd. has described proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to an interleukin-1 receptor-associated kinase 4 (IRAK-4) targeting moiety via a linker reported to be useful for the treatment of cancer, rheumatoid arthritis, renal disorders, multiple sclerosis, alopecia areata, urticaria, psoriasis and chronic obstructive pulmonary disease (COPD), among others.
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