Manufacturing, Marketing And Distribution Agreements Between Biotech And Pharmaceutical Companies: Dec 22, 2005-Feb. 22, 2006

Biotech Co.*
(Country;
Symbol)

Pharma Co.
(Country)

Product

Terms/Details (Date)

Align
Pharmaceuticals
Inc.*

PDI Inc.

Three-year deal under which PDI will provide marketing services for three oncology products from Align

PDI initially will provide a sales team of 40 representatives; the products are Numoi- syn Lozenges and Numoisyn Liquid, for dry mouth, and Xclair, for radiation dermatitis (1/19)

Amarillo
Biosciences Inc.
(OTC
BB:AMAR)

Bumimedic Sdn. Bhd. (Malaysia; part of the Antah HealthCare Group)

Bumimedic will market ABI's low-dose interferon product in Malaysia

ABI is entitled to a series of payments through approval and production, and would get royalties on sales (1/19)

Ciphergen
Biosystems
Inc. (CIPHE)

Techcomp Holdings Ltd. (China)

Techcomp will distribute Ciphergen's ProteinChip products in China, Singapore, Malaysia, Vietnam and Indonesia

They also entered a product development and manufacturing deal for sample preparation technology and an associated device; Ciphergen would sell resulting products (1/17)

Discovery
Laboratories
Inc. (DSCO)

Laureate Pharma Inc.

Discovery is purchasing Laureate's manufacturing operations in Totowa, N.J.

Laureate has been providing manufacturing services to Discovery for more than two years; Discovery is paying $16M in cash for the facility (12/28)

DUSA
Pharmaceuticals
Inc. (DUSA)

Stiefel Laboratories Inc.

Stiefel got rights to distribute DUSA's Levulan Kerastick for photodynamic therapy in dermatology in Latin America

The deal has an initial terms of 10 years; Stiefel will take over regulatory responsibilities; terms were not disclosed (1/18)

Geron Corp.
(GERN)

Cambrex Bio Science Walkersville Inc.

Deal for the manufacture of Geron's GRNVAC1 telomerase vaccine

The vaccine is comprised of autologous dendritic cells loaded ex vivo with telomerase mRNA; terms of the deal were not disclosed (2/13)

Molecular
Insight
Pharmaceuticals
Inc.*

MDS Nordion (Canada)

Six-year deal under which MDS will manufacture and supply Zemiva for MIPI

The molecular imaging agent is being developed for cardiac ischemia; terms of the deal were not disclosed (2/16)

Pharmaxis
Ltd. (Australia;
PXSL)

Nigaard Pharma A/S (Norway)

Nigaard got marketing rights to Aridol in the Scandinavian countries

Aridol is an asthma management tool; terms of the deal were not disclosed (1/18)

TopoTarget
A/S (Denmark;
CSE:TOPO)

Undisclosed company

The unnamed company will promote TopoTarget's Savene in Austria and four Eastern European countries

The drug is being developed for treating accidental extravasations of anthracycline drugs; launch is anticipated late in 2006 (12/22)

Viventia
Biotech
Inc.* (Canada)

Dowpharma

Viventia licensed rights to use Dow's Pfenex Expression Technology in antibody production

Viventia will use the technology in up to six compounds; Dow is entitled to milestone and royalty payments in the deal (2/14)

Notes:

^# The information in the chart does not cover agricultural agreements or those between biotech companies.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

CSE = Copenhagen Stock Exchange; OTC BB = Over-the-Counter Bulletin Board.