BioWorld
www.bioworld.com/articles/490012

AGRIDYNE HAS TWO PATENTS ALLOWED, GETS SBIR GRANT

April 5, 1994

The U.S. Patent and Trademark Office has allowed two AgriDyneTechnologies patents related to the company's bioinsecticidemanufacturing process. The Salt Lake City-based company is workingto develop environmentally compatible bioinsecticides usingcompounds derived from the neem tree, which is native to India andother tropical countries.The first patent is for a refining process that removes fungalcontaminants found in neem seeds from the company's neem extract.The process is used in the manufacture of technical-gradeazadirachtin, which is used in the production of the company'sbioinsecticides.The second patent is for a method of producing stable insecticideformulations containing high concentrations of azadirachtin. Higher-concentration formulations provide for greater economies in thehandling and use of pest control products, particularly when treatinglarge-acreage crops such as vegetables, fruits, cotton and soybeans.AgriDyne also has received a $63,000 Small Business InnovationResearch (SBIR) grant from the National Science Foundation to studythe possibility of producing azadirachtin from tissue-cultured cells ofthe tropical neem tree rather than extracting the compound from neemseeds. The grant will be used for a six-month validation study, whichcould be expanded to a larger two-year study. Successful cellularproduction of biologically active neem compounds would lessenAgriDyne's dependence on seasonal availability of seeds and on seedsupplies from developing countries. _ Philippa Maister

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