Investigators at the University of Copenhagen and affiliated organizations presented data from a study that aimed to validate differentially expressed genes (DEGs) in mesial temporal lobe epilepsy (mTLE) as potential new targets.
Researchers from University College Dublin and affiliated organizations presented data from a study that aimed to assess the role of α-melanocyte-stimulatory hormone (α-MSH) in diabetes.
Scientists at Surface Oncology Inc. described data from a study that aimed to evaluate the role of IL-27, a heterodimeric cytokine that plays a role in controlling the intensity and duration of immune system responses, in cancer therapy resistance.
Researchers have designed a 3D model of lung cancer that is composed of bronchial epithelial, fibroblasts, epithelial, lung adenocarcinoma and immune cells grown in different layers in a matrigel.
Researchers from Sun Yat-sen University, Southern Medical University and Gannan Medical University reported the discovery of novel quinazoline-based KRAS G12C inhibitors as potential anticancer agents.
Polycomb repressive complex 2 (PRC2) is composed of several subunits, such as EZH2, EED and SUZ12, and is a regulator of cell proliferation and development. Targeting the allosteric subunit EED may be a new approach for fully inhibiting PRC2 complex activity and addressing the limitations of EZH2 inhibition.