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BioWorld - Monday, July 14, 2025
Home » Topics » Infection » Coronavirus

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In the clinic for May 8, 2024

May 8, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Achieve, Calliditas, Eledon, Eyedna, Inmagene, Mirum, Moleculin, Neurogene, Neurosense, Rion, Traws, Verve.
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Coronavirus, mRNA and syringe
Infection

Astrazeneca presents data on mRNA VLP SARS-CoV-2 vaccine in animal models

May 3, 2024
There is still a need for developing more potent and broadly neutralizing vaccines against SARS-CoV-2 with improved durability. At the recent ESCMID meeting, Astrazeneca plc presented a new mRNA vaccine against the SARS-CoV-2 virus that encodes for self-assembling virus-like particle (VLP) antigens.
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Infection

European researchers patent PROTACs for SARS-CoV-2

May 2, 2024
Tocris Cookson Ltd., Helmholtz Zentrum fur Infektionsforschung GmbH and University of Lübeck have described proteolysis targeting chimeras (PROTACs) comprising cereblon (CRBN) ligands covalently bonded to non-structural protein 3 (nsp3; PL-PRO) (SARS-CoV-2; COVID-19 virus) targeting moiety through linker reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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WHO pandemic deal doesn’t protect developing countries, groups say

April 30, 2024
By Tamra Sami
The latest World Health Organization’s (WHO) Pandemic Agreement falls short of protecting all countries in future pandemics, said international patient groups and public health organizations.
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Infection

Jun-12682, a SARS-CoV-2 PLpro inhibitor with potent antiviral activity in mice

April 30, 2024
Researchers from State University of New Jersey (Rutgers) and Oklahoma State University have published preclinical data for a novel a SARS-CoV-2 papain-like protease (PLpro) inhibitor being developed as an antiviral candidate for the treatment of COVID-19.
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Regulatory actions for April 29, 2024

April 29, 2024
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Amgen, Apellis, Avistone, Biogen, Bristol Myers Squibb, Gilead, Hutchmed, Johnson & Johnson, Novartis, Pfizer, Ractigen, Sobi, Takeda.
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Other news to note for April 29, 2024

April 29, 2024
Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allogene, Biosenic, Biovie, Immunoengineering, Moderna, Mosaic Immunoengineering, Oncotelic, Signalchem, Sino Biological.
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In the clinic for April 29, 2024

April 29, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aligos, Arbele, Biocardia, Caliway, Can-Fite, Nkgen, Recce.
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Regulatory actions for April 24, 2024

April 24, 2024
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Abeona, Astrazeneca, Averoa, Beigene, Edgewise, Immunitybio, Innocan, Medivir, Oncoc4, Revive, Tiziana.
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Regulatory actions for April 19, 2024

April 19, 2024
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Asklepios, Bayer, Imunon and Lumicell. 
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