DUBLIN – The Coalition for Epidemic Preparedness Innovations (CEPI), an international public-private partnership raising $1 billion to incentivize the development of vaccines for neglected infectious diseases, has made its first big bet – a contract, worth up to $37.5 million, with Themis Bioscience GmbH to develop vaccines against Lassa virus and Middle East respiratory syndrome-related coronavirus (MERS-CoV).
Metastases cause a large majority of cancer deaths, and understanding their mechanisms might offer therapeutic opportunities. A team from Case Western Reserve University investigated a possible role of enhancers, regulatory DNA elements that can influence the transcription of downstream genes.
LONDON – A $1 billion program to develop vaccines against emerging infectious diseases that, like Zika and Ebola viruses, have the potential to cause serious epidemics, will be launched at the World Economic Forum in Davos, Switzerland.
Mitochondrial DNA with mutations was sometimes preferentially replicated after spindle transfer to donor eggs, with the end result that the mutated mitochondria were once again dominant after transplantation.