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BioWorld - Monday, March 27, 2023
Home » Topics » Infection » Coronavirus

Coronavirus
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Free access to BioWorld coronavirus articles

March 24, 2023
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The articles in this collection are from BioWorld’s ongoing coverage of the COVID-19 coronavirus pandemic. They are available for free with registration. Note that we have added three critical tables, which are continuously updated:

Vaccines and therapeutics in development
Diagnostics with U.S. FDA emergency use authorization
Clinical trials of biopharma products affected by COVID-19
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Infection

Nanjing Zhihe Pharmaceutical presents new cytidine derivatives for viral infections

March 24, 2023
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Nanjing Zhihe Pharmaceutical Technology Co. Ltd. has divulged cytidine derivatives reported to be useful for the treatment of viral infections.
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China greenlights CSPC’s mRNA COVID-19 vaccine for emergency use

March 23, 2023
By Zhang Mengying
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CSPC Pharmaceutical Group Ltd.’s COVID-19 mRNA vaccine, SYS-6006, has been included for emergency use by the NMPA, the company said on March 22, marking the first domestically developed COVID-19 mRNA vaccine approved for use in China.
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Infection

UT-Battelle presents new SARS-CoV-2 PLpro inhibitors

March 23, 2023
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UT-Battelle LLC has divulged covalent nonstructural protein 3 (nsp3; PLpro) (SARS-CoV) inhibitors reported to be useful for the treatment of coronavirus acute respiratory syndrome.
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Colorized transmission electron micrograph of SARS-CoV-2 (UK B.1.1.7 variant).
Infection

Researchers find mSWI/SNF complexes play role in SARS-CoV-2 infection

March 23, 2023
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Current prophylactic and therapeutic approaches for SARS-CoV-2 are effective, but the need for new approaches with broad activity makes virus-host interactions an essential piece to look at.
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Other news to note for March 23, 2023

March 23, 2023
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Additional early-stage research and drug discovery news in brief, from: 280Bio, Evolveimmune Therapeutics, Imunon, Pepgen, Psycheceutical Bioscience.
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Moderna vaccine vial and syringe on tray

Not just Moderna on the HELP hot seat

March 22, 2023
By Mari Serebrov
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While Moderna Inc. CEO Stéphane Bancel was the one on the hot seat at a March 22 hearing before the U.S. Senate Health, Education, Labor and Pensions (HELP) Committee, biopharma profitability in general, and capitalism itself, came under fire as committee Chair Bernie Sanders (I-Vt.) railed about corporate greed in the sector.
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Regulatory actions for March 21, 2023

March 21, 2023
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Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Antengene, Aquavit, Arrowhead, Aviceda, Boan, Diamond, Enlivex, Fore, Ichnos, Intellia, Jiangsu Recbio, Luye, Mereo, Prestige, Sanofi, Sensei.
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Infection

Arbutus Biopharma presents data on AB-343 for SARS-CoV-2 infection

March 21, 2023
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For COVID-19, the limited durability of vaccines requires multiple injections, and their effectiveness is continuously challenged by emerging new spike variants of the virus. The SARS-CoV-2 main protease Mpro plays a role in major polyprotein processing events and is essential for viral replication.
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Regulatory actions for March 20, 2023

March 20, 2023
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Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Ipsen, Kuria, Likang, Novartis, Pfizer, Sarepta.
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