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BioWorld - Saturday, April 1, 2023
Home » Topics » Infection » Coronavirus

Coronavirus
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SARS-CoV-2 virus particles
Infection

Genetically attenuated SARS-CoV-2 protects against pneumonia in Syrian hamster model of COVID-19

Dec. 27, 2022
No Comments
Eleven vaccines have now been approved by the World Health Organization for preventing COVID-19, but all exhibit drastically reduced activities after 6 months. Unlike vaccines that express only the spike protein as the immunogen, live attenuated vaccines have the potential to confer a broader and more durable protection.
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Colorized transmission electron micrograph of SARS-CoV-2 (UK B.1.1.7 variant).
Immune

Oragenics reports toxicology findings with NT-CoV2-1 intranasal COVID-19 vaccine candidate

Dec. 23, 2022
No Comments
Oragenics Inc. has announced results from its...
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Colorful illustration of the heart

Neuome Peptides develops platform to detect cardiovascular diseases

Dec. 22, 2022
By Zhang Mengying
No Comments
A new acute coronary syndrome detection system developed by Neuome Peptides Pte. Ltd.’s aims to make tests for the frequently lethal condition faster, more precise and less invasive. Neuome’s Truheart is a point-of-care assay for cardiovascular disease that is used in the company’s established Instadetect assay development platform. The assay measures the biomarkers troponins I and T and myoglobin.
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Regulatory actions for Dec. 22, 2022

Dec. 22, 2022
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Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Abivax, Actinogen, ADC, Affimed, Akebia, Aldeyra, Alnylam, Alvotech, Aquestive, Astrazeneca, Benevolentai, Edesa, Genentech, Genmab, Gilead, Gradalis, Iaso, Innocare, Merck, Mirati, Onkyo, Outlook, Pfizer, Radius, Regenxbio, Sanofi, Sobi.
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In the clinic for Dec. 22, 2022

Dec. 22, 2022
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Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aerami, Akero, Armata, Astrazeneca, Bavarian Nordic, Beckley, Biontech, Bridgebio, Chemomab, Contrafect, Exelixis, Imago, Imbrium, Kempharm, Lexicon, Melt, Minovia, Mirata, Osivax, RQ, Sirnaomics, Small, Sosei, Vir, Viridian, Zynerba.
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Infection

Emory University describes new NHC analogues for viral infections

Dec. 22, 2022
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Emory University has identified deuterated and/or methylated N4-hydroxycytidine (NHC) analogues reported to be useful for the treatment of viral infections.
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Coronavirus, mRNA and syringe
Immune

Ethris and Diosynvax collaborate to develop mRNA vaccine candidate against betacoronaviruses

Dec. 22, 2022
No Comments
Ethris GmbH has entered into a collaboration with Diosynvax Ltd. to jointly develop a protective mRNA vaccine candidate against a broad range of betacoronaviruses utilizing the company's highly differentiated mRNA modification and design technologies as well as its lipidoid nanoparticle (LNP) and stabilization platforms.
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Coronavirus and antibodies
Immune

RQ Bio's monoclonal antibody to prevent COVID-19 enters clinic as part of antibody combination

Dec. 22, 2022
No Comments
RQ Biotechnology Ltd. (RQ Bio) has announced that the first of its discovered monoclonal antibodies to prevent COVID-19 in vulnerable patients, AZD-3152, has entered clinical trials.
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In the clinic for Dec. 21, 2022

Dec. 21, 2022
No Comments
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Altimmune, Arcus, Athenex, Biolinerx, Erasca, Journey Medical, Magenta, Nanology, Nykode, Oncotherapeutics, Quantum Leap, Regimmune, Satsuma, Simcere, Takeda, Ultimovacs, Verona.
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SARS-CoV-2 illustration turns from blue to red

WTO divided over expanding COVID-19 IP waiver

Dec. 20, 2022
By Mari Serebrov
No Comments
One of the big regulatory and pandemic stories of 2022 with global impact was the June 17 World Trade Organization’s (WTO) agreement on a five-year intellectual property (IP) waiver for COVID-19 vaccines and their components.
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