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BioWorld - Friday, December 1, 2023
Home » Topics » Infection » Coronavirus

Coronavirus
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Infection

Arbutus Biopharma presents new RNA polymerase inhibitors for coronavirus infection

Sep. 7, 2023
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Arbutus Biopharma Corp. has divulged RNA polymerase inhibitors reported to be useful for the treatment of coronavirus infection.
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Regulatory actions for Sept. 6, 2023

Sep. 6, 2023
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Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Arcturus, Aspargo, Astrazeneca, CSL, Inmune, Italfarmaco, Krystal, Nykode, Uniqure, Viatris, Wave, X4.
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In the clinic for Sept. 6, 2023

Sep. 6, 2023
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Clinical updates, including trial initiations, enrollment status and data readouts and publications: ABM, ACM, Addex, Biohaven, Cantargia, Eledon, Escocap, Genmab, Iliad, Insmed, Invlos, Mindbio, Nuvalent, Oncopeptides, Oncorena, Plus, Rallybio, Sareum, Seagen, Stoke, Tonix, Tris.
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In the clinic for Sept. 5, 2023

Sep. 5, 2023
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Clinical updates, including trial initiations, enrollment status and data readouts and publications: Acticor, AI, Bavarian Nordic, Carisma, Nuvox, Roche, Tvardi.
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Regulatory actions for Sept. 1, 2023

Sep. 1, 2023
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Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Alcresta, Astrazeneca, Biontech, Daiichi Sankyo, Mallinckrodt, Pfizer.
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Illustration of COVID-19 virus cells affecting brain

UK Phosp study finds biomarkers predictive of long COVID cognitive defects

Aug. 31, 2023
By Nuala Moran
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Blood biomarkers have been found in patients hospitalized with acute COVID-19 that are predictive of the cognitive defects of long COVID. Post COVID-19 deficits in cognition, including brain fog, are common and debilitating. They are also clinically complex, with both objective and subjective components. In the U.K., one in eight patients received their first ever neurological or psychiatric diagnosis within six months following COVID-19.
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Infection

SARS-CoV-2 Mpro inhibitors reported in Wistar Institute of Anatomy & Biology patent

Aug. 31, 2023
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Wistar Institute of Anatomy & Biology has synthesized new 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors for the treatment of SARS-CoV-2 infection (COVID-19).
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Litigation continues over COVID-19 mRNA vaccines

Aug. 29, 2023
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Biontech SE and Pfizer Inc. filed a petition with the U.S. Patent Trial and Appeal Board for an inter partes review against Moderna Inc., the latest move in an ongoing patent battle over the mRNA technology used to develop COVID-19 vaccines.
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Colorized transmission electron micrograph of SARS-CoV-2.
Infection

Next-generation oral SARS-CoV-2 Mpro inhibitor disclosed

Aug. 29, 2023
No Comments
Viral proteases are well-established therapeutic targets in HIV and hepatitis C virus infections. Following the recent COVID-19 pandemic, one of the strategies in place is SARS-CoV-2 main protease (Mpro) inhibition, given the crucial role of SARS-CoV-2 Mpro in the replication of the virus.
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Regulatory actions for Aug. 25, 2023

Aug. 25, 2023
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Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Akebia, Alentis, Astrazeneca, Bioxytran, Collegium, Comanche, Gilead, Merck, Novaliq, Taysha Gene Therapies.
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