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Remember how Ras is a frequently mutated oncogene in solid tumors? Well, it turns out Ras plays a role in those memories, too. In the Jan. 13, 2020, online issue of the Proceedings of the National Academy of Sciences, scientists at the Scripps Research Institute in Juniper, Fla., reported on the discovery that Ras signals through Raf and then Rho kinase to control whether memory is short- or long-term.
Remember how Ras is a frequently mutated oncogene in solid tumors? Well, it turns out Ras plays a role in those memories, too. In the Jan. 13, 2020, online issue of the Proceedings of the National Academy of Sciences, scientists at the Scripps Research Institute in Juniper, Fla., reported on the discovery that Ras signals through Raf and then Rho kinase to control whether memory is short or long-term.
Children are more susceptible to developing allergic asthma than adults. An estimated 6 million children have allergic asthma, making asthma one of the most common long-term diseases of childhood. Asthma is potentially life-threatening, yet there is no cure, rather only management of symptoms. Progress in understanding the disease was reported in the Dec 17, 2019, issue of Immunity.
Birth defects in mitochondrial genes can lead to devastating pediatric disorders with death within a year of birth, and when the dysfunction is milder it can lead to various types of degenerative conditions, including neurodegeneration.
Three new studies conducted as part of the second phase of the Human Microbiome Project (HMP) could lead to improvements in the risk prediction, identification and classification of the conditions they are investigating.
In a first, researchers were able to use a genetically modified specific lytic phage strain to stop an otherwise generally lethal drug-resistant Mycobacterium abscessus infection in a cystic fibrosis patient after persistent infections, as reported in the May 8, 2019, issue of Nature Medicine.
In utero administration of a gene-editing technology in a mouse model has been able to correct a mutation that causes fatal respiratory failure in the animals within hours of birth if left untreated. For now, the work is proof of concept, and survival rates in treated animals remained low. But the fact that prenatal gene editing was able to prevent an otherwise lethal disease at all has encouraging implications.
BEIJING – China will kickstart a phase III trial Feb. 3 to determine whether patients with 2019-nCoV can be treated with Gilead Sciences Inc.’s NUC inhibitor,...
HONG KONG – In another example that communication is proving as difficult as containment in the current coronavirus outbreak, China’s state media reported, to...
HONG KONG – A team of researchers at Hong Kong University of Science and Technology (HKUST) claim to have invented the world’s fastest portable 2019-nCoV...
HONG KONG – As drug developers are racing to find a cure for the new coronavirus, researchers in Hong Kong claim to have made major headway in the development of...
BEIJING – Chinese regulators are speeding up to approve more test kits for the deadly coronavirus that already has killed 170 people and infected more than 7,700...
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