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BioWorld - Sunday, May 24, 2026
Home » Keywords » von Willebrand disease

Items Tagged with 'von Willebrand disease'

ARTICLES

IPO and digital hologram with business icons

Hemab prices $301M in latest upsized biopharma IPO

May 1, 2026
By Jennifer Boggs
No Comments
Continuing biopharma’s IPO resurgence in 2026, Hemab Therapeutics Holdings Inc. priced an upsized offering of 16.75 million shares at $18 per share, the high end of its proposed price range, for gross proceeds of $301.5 million. Another $45 million could come if underwriters exercise their full overallotment.
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3D illustration of platelets in the boodstream
Hematologic

Tangram’s TGM-148 demonstrates pan-bleeding disorder therapeutic potential

Feb. 6, 2026
No Comments
Researchers at Tangram Therapeutics Inc. have presented preclinical safety and efficacy data for TGM-148 in a model of von Willebrand disease.
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Hematologic

Preclinical results of anti-ADAMTS13 antibody in acquired von Willebrand syndrome

Dec. 29, 2025
No Comments
The acquired von Willebrand syndrome (AVWS) is a rare bleeding disorder with laboratory findings similar to those of inherited von Willebrand disease. Researchers from the Nara Medical University and collaborating institutions presented a potential therapeutic approach for AVWS.
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Art concept for monoclonal antibodies
Hematologic

Hemab presents data for HMB-002 in von Willebrand disease

June 27, 2025
No Comments
Hemab ApS recently presented preclinical data on its human monoclonal antibody against von Willebrand factor (vWF), HMB-002, for the treatment of von Willebrand disease.
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Promising Star formations draw investors in $90M oversubscribed series C

Sep. 5, 2023
By Jennifer Boggs
Star Therapeutics Inc. brought on board six new investors in its oversubscribed $90 million series C round, raising the company’s total funding to more than $190 million since its founding in 2018 to advance in-house drug discovery efforts via formation of portfolio companies. Since emerging from stealth in early 2022, Star has launched two aptly named companies, Electra Therapeutics Inc. and Vega Therapeutics Inc., with plans to unveil additional ventures arising from its antibody discovery efforts.
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Hemab, ‘an Alexion five years from now,’ closes $135M series B

Feb. 21, 2023
By Cormac Sheridan
Hemab Therapeutics ApS raised $135 million in a series B funding round to continue its broad effort to build a company focused on developing prophylactic therapies for neglected bleeding and thrombotic disorders. The new cash brings its total equity raise to $190 million.
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Red and white blood cells
Hematologic

VGA-39: an anti-protein S antibody for treating bleeding disorders

Dec. 14, 2022
Vega Therapeutics Inc. has reported promising preclinical data on VGA-039, a first-in-class monoclonal antibody directed against human protein S (ProS) that inhibits ProS cofactor activity for tissue factor pathway inhibitor α (TFPIα) and activated protein C (aPC), thus enhancing thrombin generation by acting on both the initiation (TFPIα) and propagation (aPC) phases of coagulation for potential activity against various bleeding disorders.
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Red blood cells

Another star is born: Vega Therapeutics targets protein S for bleeding disorders

Dec. 6, 2022
By Cormac Sheridan
Vega Therapeutics Inc. emerged from stealth in advance of a podium presentation at this year’s American Society of Hematology meeting in New Orleans. The company, a spin-out from Star Therapeutics Inc., will disclose preclinical data on its lead drug candidate VGA-039, a first-in-class antibody in development for von Willebrand disease.
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Hematologic DNA blood test
Newco news

Hemab targeting rare bleeding disorders with $55M series A

July 22, 2021
By Nuala Moran
LONDON – Hemab ApS has closed a $55 million series A to take forward treatments for bleeding and thrombosis disorders based on antibodies in-licensed from Novo Nordisk A/S, where the newco’s founder, Johan Henrik Faber, previously led hemophilia drug research.
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