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In The Clinic NEWS

Interim results from the open-label phase I/II study of BMN 270, Biomarin Pharmaceutical Inc.’s gene therapy to treat severe hemophilia A, showed the candidate outperformed expectations both in terms of efficacy and clinical improvements.


A site investigator in the failed phase III study by Taurx Therapeutics Ltd. told BioWorld Today that Alzheimer's disease (AD) "absolutely" will best be attacked by a combination approach, despite the finding that tau aggregation blocker LMTX when used along with the standard, "modestly" beneficial AD drugs "doesn't add any value."

Tokai Pharmaceuticals Inc. called off a pivotal phase III trial comparing its triple-acting prostate cancer drug, galeterone, to Xtandi (enzalutamide, Medivation Inc.) after a data monitoring committee determined the trial was unlikely to meet its primary endpoint.

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