https://www.bioworld.com/rss en-us http://www.bioworld.com/articles/725002 Mon, 13 Oct 2025 11:00:00 -0400 https://www.bioworld.com/articles/725002-drug-resistance-rising-one-in-six-infections-show-no-response Art concept for antimicrobial research http://www.bioworld.com/articles/723685 Fri, 29 Aug 2025 09:00:00 -0400 https://www.bioworld.com/articles/723685-tyra-200-a-potent-oral-fgfr-inhibitor-tackling-resistance-mutations Illustration of double helix http://www.bioworld.com/articles/722717 Thu, 31 Jul 2025 09:00:00 -0400 https://www.bioworld.com/articles/722717-kiwa-antiviral-defenses-dissected-to-disarm-bacteria Microscopic image of a bacteria infected by phage (left) and illustration of a phage attaching to a bacterial cell Left: Bacteria infected by phage; the dots show phages replicating. Right: This illustration shows a phage attaching to a bacterial cell. The Kiwa defense system (shown in yellow, green and blue) detects the threat and binds the invading DNA, preventing the phage from hijacking the cell. Credit: University of Southampton. Klebsiella pneumoniae carbapenemase).]]> http://www.bioworld.com/articles/717292 Fri, 14 Feb 2025 09:00:00 -0500 https://www.bioworld.com/articles/717292-boronic-acid-inhibitors-restore-cefepime-efficacy-in-multidrug-resistant-kpc-producing-emk-pneumoniae-em Klebsiella pneumoniae colonies in petri dish http://www.bioworld.com/articles/717285 Fri, 14 Feb 2025 09:00:00 -0500 https://www.bioworld.com/articles/717285-apd-94-a-dual-functional-inhibitor-of-bmi-1-and-tubulin http://www.bioworld.com/articles/717241 Thu, 13 Feb 2025 09:00:00 -0500 https://www.bioworld.com/articles/717241-gates-foundation-novo-nordisk-foundation-and-wellcome-set-sights-on-antimicrobial-resistance Bacterial colonies in petri dishes http://www.bioworld.com/articles/716743 Fri, 31 Jan 2025 09:00:00 -0500 https://www.bioworld.com/articles/716743-combined-strategy-can-prevent-pancreatic-cancer-drug-resistance 3D illustration of pancreatic cancer Citrobacter freundii. This discovery underscores the ongoing challenge of antibiotic resistance in bacterial pathogens.]]> http://www.bioworld.com/articles/715886 Fri, 03 Jan 2025 09:00:00 -0500 https://www.bioworld.com/articles/715886-new-carbapenemase-identified-in-emc-freundii-em-raises-resistance-concerns Nature lay all the cards on the table, revealing ecDNAs’ content, their origin, their inheritance, their influence in cancer, and a way to combat them.]]> http://www.bioworld.com/articles/714456 Wed, 13 Nov 2024 10:00:00 -0500 https://www.bioworld.com/articles/714456-extrachromosomal-dna-acts-as-joker-for-cancer-cells Illustration of ecDNA inheritance in cancer ecDNAs that link together to enhance cancer cell growth tend to be inherited together by daughter cells after cell division (left). In contrast, ecDNAs that are inherited randomly give more genetic variability but may be less likely to spur tumor growth (right). Credit: Emily Moskal/Stanford Medicine Nature lay all the cards on the table, revealing ecDNAs’ content, their origin, their inheritance, their influence in cancer, and a way to combat them.]]> http://www.bioworld.com/articles/714423 Tue, 12 Nov 2024 12:00:00 -0500 https://www.bioworld.com/articles/714423-extrachromosomal-dna-acts-as-joker-for-cancer-cells Illustration of ecDNA inheritance in cancer ecDNAs that link together to enhance cancer cell growth tend to be inherited together by daughter cells after cell division (left). In contrast, ecDNAs that are inherited randomly give more genetic variability but may be less likely to spur tumor growth (right). Credit: Emily Moskal/Stanford Medicine Nature lay all the cards on the table, revealing ecDNAs’ content, their origin, their inheritance, their influence in cancer, and a way to combat them.]]> http://www.bioworld.com/articles/714318 Mon, 11 Nov 2024 09:00:00 -0500 https://www.bioworld.com/articles/714318-extrachromosomal-dna-acts-as-joker-for-cancer-cells Illustration of ecDNA inheritance in cancer ecDNAs that link together to enhance cancer cell growth tend to be inherited together by daughter cells after cell division (left). In contrast, ecDNAs that are inherited randomly give more genetic variability but may be less likely to spur tumor growth (right). Credit: Emily Moskal/Stanford Medicine http://www.bioworld.com/articles/713913 Tue, 29 Oct 2024 09:00:00 -0400 https://www.bioworld.com/articles/713913-genome-and-co-stresses-cntn4-app-as-next-immuno-oncology-target Concept art for targeting cancer http://www.bioworld.com/articles/711836 Mon, 26 Aug 2024 09:00:00 -0400 https://www.bioworld.com/articles/711836-novel-quinolone-derivative-tackles-microbial-resistance Bacterial colonies in petri dishes http://www.bioworld.com/articles/711170 Fri, 02 Aug 2024 08:00:00 -0400 https://www.bioworld.com/articles/711170-deazaflavin-analog-reverses-mrp1-mediated-drug-resistance Drug discovery illustration http://www.bioworld.com/articles/711094 Thu, 01 Aug 2024 09:00:00 -0400 https://www.bioworld.com/articles/711094-nbs1-lactylation-inhibition-could-avoid-chemotherapy-resistance http://www.bioworld.com/articles/710715 Tue, 23 Jul 2024 09:00:00 -0400 https://www.bioworld.com/articles/710715-cancer-cells-adapt-to-resist-therapy-step-by-step Illustration of a cluster of ovarian cancer cells http://www.bioworld.com/articles/705746 Mon, 26 Feb 2024 09:00:00 -0500 https://www.bioworld.com/articles/705746-novel-engineered-lysin-cf-370-is-highly-effective-against-resistant-pathogens http://www.bioworld.com/articles/705640 Fri, 09 Feb 2024 12:00:00 -0500 https://www.bioworld.com/articles/705640-enzyme-degrader-could-avoid-drug-resistance-in-b-cell-cancers Non-Hodgkin lymphoma cells in the blood flow http://www.bioworld.com/articles/705482 Thu, 08 Feb 2024 09:00:00 -0500 https://www.bioworld.com/articles/705482-enzyme-degrader-could-avoid-drug-resistance-in-b-cell-cancers Non-Hodgkin lymphoma cells in the blood flow Acinetobacter baumannii. The most advanced member of the class, zosurabalpin (RG-6006, Roche AG), was effective against multiple A. baumannii strains, including carbapenem-resistant and multidrug-resistant strains.]]> http://www.bioworld.com/articles/704312 Thu, 04 Jan 2024 09:00:55 -0500 https://www.bioworld.com/articles/704312-old-fashioned-screening-approach-yields-new-antibiotic-class Acinetobacter spp. A 3D computer-generated image of a group of multidrug-resistant Acinetobacter spp. bacteria. The artistic recreation was based upon scanning electron microscopic imagery. Credit: CDC/Antibiotic Resistance Coordination and Strategy Unit; James Archer, medical illustrator Nature on Dec. 20, 2023. In animal testing, compounds identified via the method showed that they had activity against drug-resistant gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA), one of the most serious bacterial public health threats.]]> http://www.bioworld.com/articles/703901 Wed, 20 Dec 2023 09:00:00 -0500 https://www.bioworld.com/articles/703901-explainable-ai-finds-new-class-of-antibiotics Bacteria targeted by technology concept art Using a type of artificial intelligence known as deep learning, MIT researchers have discovered a class of compounds that can kill a drug-resistant bacterium that causes more than 10,000 deaths in the U.S. every year. Credit: Christine Daniloff, MIT; Janice Haney Carr, CDC; iStock http://www.bioworld.com/articles/701271 Thu, 28 Sep 2023 12:00:00 -0400 https://www.bioworld.com/articles/701271-mission-accomplished-mission-bio-launches-mrd-assay-for-blood-cancer 3D illustration of acute lymphoblastic leukemia in blood. http://www.bioworld.com/articles/700277 Wed, 23 Aug 2023 09:00:00 -0400 https://www.bioworld.com/articles/700277-cage-fight-could-make-for-resistance-resistant-antibiotic Clovibactin art concept Clovibactin uses an unsual cage-like binding motif to tightly wrap around pyrophosphate-containing lipids in bacterial cell membranes. Credit: Markus Weingarth, Utrecht University http://www.bioworld.com/articles/699902 Fri, 11 Aug 2023 09:00:00 -0400 https://www.bioworld.com/articles/699902-unraveling-mechanisms-of-hiv-1-integrase-resistance-to-dtg-to-design-more-effective-drugs Transmission electron micrograph of HIV particles HIV-1 virus particles (colorized yellow) replicating from an HIV-infected H9 T cell (pink). Credit: NIAID, NIH http://www.bioworld.com/articles/699821 Thu, 10 Aug 2023 09:00:00 -0400 https://www.bioworld.com/articles/699821-improved-lpxc-inhibitor-antibiotic-ready-for-human-trials http://www.bioworld.com/articles/699298 Mon, 24 Jul 2023 09:00:00 -0400 https://www.bioworld.com/articles/699298-communication-system-discovery-explains-how-bacterial-cells-evolve Mycoplasma pneumoniae to treat Pseudomonas aeruginosa, the chief culprit in ventilator-associated pneumonia (VAP).]]> http://www.bioworld.com/articles/693484 Fri, 20 Jan 2023 09:00:00 -0500 https://www.bioworld.com/articles/693484-what-stops-a-bad-guy-in-the-lung-a-good-guy-in-the-lung-of-course Microscopic view of P. aeruginosa infection of mouse lung Cross-section of a mouse lung infected with P. aeruginosa and treated with engineered M. pneumoniae. Credit: Rocco Mazzolini/CRG http://www.bioworld.com/articles/692296 Thu, 08 Dec 2022 13:00:00 -0500 https://www.bioworld.com/articles/692296-researchers-identify-new-class-of-antibiotic-resistance-mechanism Antibiotic resistant bacteria inside a biofilm http://www.bioworld.com/articles/692076 Wed, 07 Dec 2022 09:00:00 -0500 https://www.bioworld.com/articles/692076-researchers-identify-new-class-of-antibiotic-resistance-mechanism http://www.bioworld.com/articles/691007 Thu, 27 Oct 2022 09:00:00 -0400 https://www.bioworld.com/articles/691007-novel-ocotillol-derivative-shows-efficacy-in-preclinical-models-of-p-gp-mediated-mdr