American College of Rheumatology https://www.bioworld.com/rss en-us QEL-005 restores homeostasis in inflammatory disorders http://www.bioworld.com/articles/726021 Wed, 12 Nov 2025 08:00:00 -0500 https://www.bioworld.com/articles/726021-qel-005-restores-homeostasis-in-inflammatory-disorders Arthritis pain illustration NKX-019 induces CD19 depletion in autoimmune disease http://www.bioworld.com/articles/726064 Tue, 11 Nov 2025 08:00:00 -0500 https://www.bioworld.com/articles/726064-nkx-019-induces-cd19-depletion-in-autoimmune-disease CDR-Life’s new dual-targeting T-cell engager http://www.bioworld.com/articles/725927 Mon, 10 Nov 2025 08:00:00 -0500 https://www.bioworld.com/articles/725927-cdr-lifes-new-dual-targeting-t-cell-engager Illustration of a T cell Helixon’s HXN-1022 ameliorates autoimmune disease symptoms http://www.bioworld.com/articles/725814 Tue, 04 Nov 2025 08:00:00 -0500 https://www.bioworld.com/articles/725814-helixons-hxn-1022-ameliorates-autoimmune-disease-symptoms Person scratching arm IBI-3034 shows promise for B-cell-related autoimmune diseases http://www.bioworld.com/articles/725754 Mon, 03 Nov 2025 08:00:00 -0500 https://www.bioworld.com/articles/725754-ibi-3034-shows-promise-for-b-cell-related-autoimmune-diseases B-cell releasing antibodies KT-502 exerts B-cell depletion through CD19 targeting http://www.bioworld.com/articles/725735 Fri, 31 Oct 2025 09:00:00 -0400 https://www.bioworld.com/articles/725735-kt-502-exerts-b-cell-depletion-through-cd19-targeting IBI-3011 ameliorates gout and rheumatoid arthritis symptoms http://www.bioworld.com/articles/725715 Thu, 30 Oct 2025 09:00:00 -0400 https://www.bioworld.com/articles/725715-ibi-3011-ameliorates-gout-and-rheumatoid-arthritis-symptoms Levicept data show neurotrophin inhibitor may be disease modifying in osteoarthritis http://www.bioworld.com/articles/725578 Tue, 28 Oct 2025 11:00:00 -0400 https://www.bioworld.com/articles/725578-levicept-data-show-neurotrophin-inhibitor-may-be-disease-modifying-in-osteoarthritis Illustration of leg anatomy with target around knee S-4321, a dual-cell bidirectional antibody that agonizes inhibitory receptors at the T cell-APC synapse http://www.bioworld.com/articles/715027 Wed, 04 Dec 2024 09:00:00 -0500 https://www.bioworld.com/articles/715027-s-4321-a-dual-cell-bidirectional-antibody-that-agonizes-inhibitory-receptors-at-the-t-cell-apc-synapse Kronos Bio’s KB-7898 reduces pathological scores in inflammatory disorders http://www.bioworld.com/articles/715022 Wed, 04 Dec 2024 09:00:00 -0500 https://www.bioworld.com/articles/715022-kronos-bios-kb-7898-reduces-pathological-scores-in-inflammatory-disorders PAI-1 inhibitor MDI-2517 shows superior preclinical efficacy in systemic sclerosis models http://www.bioworld.com/articles/715008 Tue, 03 Dec 2024 09:00:00 -0500 https://www.bioworld.com/articles/715008-pai-1-inhibitor-mdi-2517-shows-superior-preclinical-efficacy-in-systemic-sclerosis-models Oral STAT3 inhibitor shows promising efficacy and safety profile in model of inflammatory arthritis http://www.bioworld.com/articles/714960 Mon, 02 Dec 2024 09:00:00 -0500 https://www.bioworld.com/articles/714960-oral-stat3-inhibitor-shows-promising-efficacy-and-safety-profile-in-model-of-inflammatory-arthritis Joint pain illustration Kyverna’s KYV-102 has potent CAR therapeutic activity http://www.bioworld.com/articles/714959 Mon, 02 Dec 2024 09:00:00 -0500 https://www.bioworld.com/articles/714959-kyvernas-kyv-102-has-potent-car-therapeutic-activity B-cell releasing antibodies M-5542 shows promise in the treatment of GVHD http://www.bioworld.com/articles/714926 Fri, 29 Nov 2024 09:00:00 -0500 https://www.bioworld.com/articles/714926-m-5542-shows-promise-in-the-treatment-of-gvhd Allogene’s ALLO-329 shows efficacy at killing CD19- and CD70-expressing cells 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https://www.bioworld.com/articles/714696-gileads-gs-6791-ameliorates-arthritis-symptoms-in-mice Joint pain TNF-α/OX40L bispecific antibody shows efficacy in models of rheumatoid arthritis http://www.bioworld.com/articles/703165 Tue, 28 Nov 2023 09:00:00 -0500 https://www.bioworld.com/articles/703165-tnf-ox40l-bispecific-antibody-shows-efficacy-in-models-of-rheumatoid-arthritis Close up of senior man holding wrist of arthritic hand Innovo Therapeutics’ INV-1498 shows efficacy in canine osteoarthritis model http://www.bioworld.com/articles/703110 Mon, 27 Nov 2023 09:00:00 -0500 https://www.bioworld.com/articles/703110-innovo-therapeutics-inv-1498-shows-efficacy-in-canine-osteoarthritis-model 3D illustration of knee joint New RIPK2 scaffolding inhibitor selectively blocks microbe-induced inflammation http://www.bioworld.com/articles/703092 Fri, 24 Nov 2023 09:00:00 -0500 https://www.bioworld.com/articles/703092-new-ripk2-scaffolding-inhibitor-selectively-blocks-microbe-induced-inflammation Arthritis pain illustration Anti-CD19 KYV-101 shows promise for autoimmune diseases http://www.bioworld.com/articles/703015 Mon, 20 Nov 2023 09:00:00 -0500 https://www.bioworld.com/articles/703015-anti-cd19-kyv-101-shows-promise-for-autoimmune-diseases Drug R&D concept image. Guangzhou Fermion Technology presents data on TYK2 inhibitor http://www.bioworld.com/articles/702977 Fri, 17 Nov 2023 09:00:00 -0500 https://www.bioworld.com/articles/702977-guangzhou-fermion-technology-presents-data-on-tyk2-inhibitor Close up of hand scratching arm with psoriasis patches TLR7-targeting antibody shows promise in SLE treatment http://www.bioworld.com/articles/702945 Thu, 16 Nov 2023 09:00:00 -0500 https://www.bioworld.com/articles/702945-tlr7-targeting-antibody-shows-promise-in-sle-treatment Active pipeline of potential new lupus therapies unfolding as ACR begins http://www.bioworld.com/articles/499853 Thu, 05 Nov 2020 12:00:00 -0500 https://www.bioworld.com/articles/499853-active-pipeline-of-potential-new-lupus-therapies-unfolding-as-acr-begins Hands illustrating pain and inflammation