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    <title>American Society of Clinical Oncology</title>
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      <title>Cas and effect: Merck’s phase III ripples HIF-2α space</title>
      <description>
        <![CDATA[Oddsmakers wasted no time figuring the market chances after Merck & Co. Inc. rolled out data from the phase III Litespark-011 study testing its oral hypoxia-inducible factor-2 alpha (HIF-2α) inhibitor, Welireg (belzutifan), when used with tyrosine kinase inhibitor Lenvima (lenvatinib, Eisai Co.) in advanced renal cell carcinoma.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729290</guid>
      <pubDate>Tue, 03 Mar 2026 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729290-cas-and-effect-mercks-phase-iii-ripples-hif-2-space</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Cancer-renal-cell-carcinoma-RCC.webp?t=1683731739" type="image/jpeg" medium="image" fileSize="219795">
        <media:title type="plain">Microscopic image of clear cell carcinoma, the most common type of renal cell carcinoma.</media:title>
      </media:content>
    </item>
    <item>
      <title>First-in-class ADC targeting DEM-TXX shows high preclinical efficacy</title>
      <description>
        <![CDATA[Researchers at DEM Biopharma Inc. reported preclinical findings demonstrating the efficacy of DEM-301, a bifunctional antibody-drug conjugate (ADC) engineered to selectively recognize and eliminate tumor cells that express DEM-TXX.]]>
      </description>
      <guid>http://www.bioworld.com/articles/728190</guid>
      <pubDate>Wed, 21 Jan 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/728190-first-in-class-adc-targeting-dem-txx-shows-high-preclinical-efficacy</link>
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        <media:title type="plain">Red and blue bispecific antibodies</media:title>
      </media:content>
    </item>
    <item>
      <title>Anti-FGFR1 therapy shows efficacy in colorectal cancer models</title>
      <description>
        <![CDATA[FGFR1 is a receptor tyrosine kinase that drives multiple intracellular signaling pathways involved in tumor cell proliferation, survival and progression. Because these pathways are frequently hyperactivated in colorectal cancer (CRC), FGFR1 represents a biologically relevant therapeutic target, and its inhibition has the potential to simultaneously suppress several oncogenic mechanisms.]]>
      </description>
      <guid>http://www.bioworld.com/articles/727909</guid>
      <pubDate>Mon, 12 Jan 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/727909-anti-fgfr1-therapy-shows-efficacy-in-colorectal-cancer-models</link>
    </item>
    <item>
      <title>3Sbio revs on with phase II data in tight PD-1/VEGF bispecific race</title>
      <description>
        <![CDATA[3Sbio Inc. reported interim phase II study results of its PD-1/VEGF bispecific antibody, SSGJ-707 – a “fabulous” asset, according to Pfizer Inc. CEO Albert Bourla, that landed in Pfizer’s cancer arsenal via a potential $6 billion deal in May, of which $1.2 billion was paid up front.]]>
      </description>
      <guid>http://www.bioworld.com/articles/721451</guid>
      <pubDate>Tue, 17 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/721451-3sbio-revs-on-with-phase-ii-data-in-tight-pd-1-vegf-bispecific-race</link>
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        <media:title type="plain">Red and blue bispecific antibodies</media:title>
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    </item>
    <item>
      <title>3Sbio revs on with phase II data in tight PD-1/VEGF bispecific race</title>
      <description>
        <![CDATA[3Sbio Inc. reported interim phase II study results of its PD-1/VEGF bispecific antibody, SSGJ-707 – a “fabulous” asset, according to Pfizer Inc. CEO Albert Bourla, that landed in Pfizer’s cancer arsenal via a potential $6 billion deal in May, of which $1.2 billion was paid up front.]]>
      </description>
      <guid>http://www.bioworld.com/articles/721001</guid>
      <pubDate>Wed, 11 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/721001-3sbio-revs-on-with-phase-ii-data-in-tight-pd-1-vegf-bispecific-race</link>
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        <media:title type="plain">Red and blue bispecific antibodies</media:title>
      </media:content>
    </item>
    <item>
      <title>Dizal's new chemical entities for lung, blood cancers</title>
      <description>
        <![CDATA[Dizal (Jiangsu) Pharmaceutical Co. Ltd.’s LYN/BTK dual inhibitor, DZD-8586, saw tumor shrinkage in 94.1% of patients with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma following Bruton's tyrosine kinase inhibitors, the company reported during an oral presentation at the American Society of Clinical Oncology (ASCO) 2025 conference.]]>
      </description>
      <guid>http://www.bioworld.com/articles/721156</guid>
      <pubDate>Tue, 10 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/721156-dizals-new-chemical-entities-for-lung-blood-cancers</link>
      <media:content url="https://www.bioworld.com/ext/resources/BW-source/2025/Xiaolin-Zhang-CEO-Dizal-6-4.webp?t=1749066829" type="image/jpeg" medium="image" fileSize="581361">
        <media:title type="plain">Xiaolin Zhang, CEO, Dizal</media:title>
        <media:description type="plain">Xiaolin Zhang, CEO, Dizal (Jiangsu) Pharmaceutical Co. Ltd.</media:description>
      </media:content>
    </item>
    <item>
      <title>ASCO 2025: Dizal's new chemical entities for lung, blood cancers</title>
      <description>
        <![CDATA[Dizal (Jiangsu) Pharmaceutical Co. Ltd.’s LYN/BTK dual inhibitor, DZD-8586, saw tumor shrinkage in 94.1% of patients with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma following Bruton's tyrosine kinase inhibitors, the company reported during an oral presentation at the American Society of Clinical Oncology (ASCO) 2025 conference.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720890</guid>
      <pubDate>Wed, 04 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720890-asco-2025-dizals-new-chemical-entities-for-lung-blood-cancers</link>
      <media:content url="https://www.bioworld.com/ext/resources/BW-source/2025/Xiaolin-Zhang-CEO-Dizal-6-4.webp?t=1749066829" type="image/jpeg" medium="image" fileSize="581361">
        <media:title type="plain">Xiaolin Zhang, CEO, Dizal</media:title>
        <media:description type="plain">Xiaolin Zhang, CEO, Dizal (Jiangsu) Pharmaceutical Co. Ltd.</media:description>
      </media:content>
    </item>
    <item>
      <title>BH-30643 targets full spectrum of EGFR-mutant lung cancer variants</title>
      <description>
        <![CDATA[The use of tyrosine kinase inhibitors (TKIs) in the treatment of epidermal growth factor receptor (EGFR)-mutant non-small-cell lung cancer (NSCLC) has not produced the same durable clinical benefits observed with next-generation targeted therapies in ALK- and ROS1-rearranged NSCLC. Given the molecular heterogeneity of EGFR-mutant NSCLC, which includes over 100 distinct mutations, there is a continued need for more effective and mutation-specific therapeutic strategies.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720871</guid>
      <pubDate>Wed, 04 Jun 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720871-bh-30643-targets-full-spectrum-of-egfr-mutant-lung-cancer-variants</link>
    </item>
    <item>
      <title>Protagonist-Takeda, Novartis post phase III wins</title>
      <description>
        <![CDATA[More phase III data coursed through the annual American Society of Clinical Oncology (ASCO) conference on Sunday, as Protagonist Therapeutics Inc. and Takeda Pharmaceutical Co. Ltd. led the charge with positive results for its potential blockbuster rusfertide in treating a rare leukemia.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720912</guid>
      <pubDate>Tue, 03 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720912-protagonist-takeda-novartis-post-phase-iii-wins</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Cancer-cell-target-destroy.webp?t=1731081970" type="image/jpeg" medium="image" fileSize="520172">
        <media:title type="plain">Illustration of cancer cell in crosshairs being destroyed</media:title>
      </media:content>
    </item>
    <item>
      <title>ASCO 2025: Verastem has positive cancer data but stock sags</title>
      <description>
        <![CDATA[New dose-escalation data from Verastem Oncology’s phase I/II cancer study in China prompted the company to say it was encouraged by the efficacy results. However, investors felt otherwise, as the stock lost about 20% of its value the day the initial results were released.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720853</guid>
      <pubDate>Tue, 03 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720853-asco-2025-verastem-has-positive-cancer-data-but-stock-sags</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/3D-illustration-of-pancreatic-cancer.webp?t=1738336763" type="image/jpeg" medium="image" fileSize="318760">
        <media:title type="plain">3D illustration of pancreatic cancer</media:title>
      </media:content>
    </item>
    <item>
      <title>THNB-3 therapeutic shows promise in LIN28-positive tumors</title>
      <description>
        <![CDATA[LIN28 is a family of RNA-binding proteins that regulate stem cell biology and pluripotency and are involved in oncogenesis through the interaction with tumor suppressor microRNA let-7. The expression of LIN28 leads to the loss of function of let-7, leading to tumorigenesis, and has been tied to tumor aggressiveness and poor survival in children with brain tumors.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720839</guid>
      <pubDate>Tue, 03 Jun 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720839-thnb-3-therapeutic-shows-promise-in-lin28-positive-tumors</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Research-and-science/Test-tube-dropper-research.webp?t=1588878251" type="image/png" medium="image" fileSize="320857">
        <media:title type="plain">Test tube, dropper, DNA illustration </media:title>
      </media:content>
    </item>
    <item>
      <title>Calidi’s novel systemic virotherapy approach demonstrates efficacy in preclinical models</title>
      <description>
        <![CDATA[The systemic virotherapy strategy involves not only the direct delivery of therapeutic payloads encoded by viruses to tumors, but also the modification of the tumor microenvironment, aiming to target both primary and metastatic lesions. At the ongoing American Society of Clinical Oncology (ASCO) meeting, researchers from Calidi Biotherapeutics Inc. reported the development of a novel approach using a selected and engineered tumor-selective strain of vaccinia virus.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720836</guid>
      <pubDate>Tue, 03 Jun 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720836-calidis-novel-systemic-virotherapy-approach-demonstrates-efficacy-in-preclinical-models</link>
    </item>
    <item>
      <title>It’s time for more trust in AI, panel says</title>
      <description>
        <![CDATA[Despite the advancement of AI and machine learning technologies and their incorporation into cancer treatment and drug development, a lack of trust and understanding of these new approaches is impeding care and treatment.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720869</guid>
      <pubDate>Mon, 02 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720869-its-time-for-more-trust-in-ai-panel-says</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/brain-computer-interface-chip-digital-AI.webp?t=1745264159" type="image/jpeg" medium="image" fileSize="236898">
        <media:title type="plain">Illustration of head with circuit board brain</media:title>
      </media:content>
    </item>
    <item>
      <title>ASCO 2025: Regeneron, Merck-Gilead drugs drop disease, death rates</title>
      <description>
        <![CDATA[New and positive phase III cancer data for two monoclonal antibodies from two pharma giants opened the second day of the American Society of Clinical Oncology (ASCO) conference this past weekend.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720820</guid>
      <pubDate>Mon, 02 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720820-asco-2025-regeneron-merck-gilead-drugs-drop-disease-death-rates</link>
    </item>
    <item>
      <title>ASCO 2025: Protagonist-Takeda, Novartis post phase III wins</title>
      <description>
        <![CDATA[More phase III data coursed through the annual American Society of Clinical Oncology (ASCO) conference on Sunday, as Protagonist Therapeutics Inc. and Takeda Pharmaceutical Co. Ltd. led the charge with positive results for its potential blockbuster rusfertide in treating a rare leukemia.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720819</guid>
      <pubDate>Mon, 02 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720819-asco-2025-protagonist-takeda-novartis-post-phase-iii-wins</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Cancer-cell-target-destroy.webp?t=1731081970" type="image/jpeg" medium="image" fileSize="520172">
        <media:title type="plain">Illustration of cancer cell in crosshairs being destroyed</media:title>
      </media:content>
    </item>
    <item>
      <title>ASCO 2025: Pancreatic cancer treatment progressing beyond chemotherapy</title>
      <description>
        <![CDATA[At the 61st American Society of Clinical Oncology (ASCO) Annual Meeting, multiple companies presented clinical trial data showing their drugs and devices helped patients with pancreatic cancer live longer or improve their ability to respond to treatment.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720818</guid>
      <pubDate>Mon, 02 Jun 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720818-asco-2025-pancreatic-cancer-treatment-progressing-beyond-chemotherapy</link>
    </item>
    <item>
      <title>ASCO 2025: It’s time for more trust in AI, panel says</title>
      <description>
        <![CDATA[Despite the advancement of AI and machine learning technologies and their incorporation into cancer treatment and drug development, a lack of trust and understanding of these new approaches is impeding care and treatment.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720609</guid>
      <pubDate>Fri, 30 May 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720609-asco-2025-its-time-for-more-trust-in-ai-panel-says</link>
    </item>
    <item>
      <title>Merus combo trounces Keytruda in head-and-neck phase II</title>
      <description>
        <![CDATA[Investor hopes rose sharply for Merus NV’s phase III trials – data should roll out next year – with bispecific antibody petosemtamab after mid-stage results impressed Wall Street in head and neck squamous cell carcinoma. Shares of Utrecht, the Netherlands-based Merus (NASDAQ:MRUS) jumped, too, closing May 23 at $55.14, up $13.54, or 33%, on interim data as of the Feb. 27 cutoff date.]]>
      </description>
      <guid>http://www.bioworld.com/articles/720464</guid>
      <pubDate>Fri, 23 May 2025 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/720464-merus-combo-trounces-keytruda-in-head-and-neck-phase-ii</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Misc/Woman-holding-neck.webp?t=1720816903" type="image/jpeg" medium="image" fileSize="245272">
        <media:title type="plain">Woman holding neck </media:title>
      </media:content>
    </item>
    <item>
      <title>TROP2 is a prognostic factor in urachal carcinoma</title>
      <description>
        <![CDATA[Urachal carcinoma is a rare cancer which lacks a standard drug therapy, and for which knowledge regarding its immunohistochemical features remains unclear. The aim of a recently reported investigation was finding potential markers and targets for urachal carcinoma based on antibody-drug conjugate targets, as well as its association with prognosis.]]>
      </description>
      <guid>http://www.bioworld.com/articles/717327</guid>
      <pubDate>Tue, 18 Feb 2025 09:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/717327-trop2-is-a-prognostic-factor-in-urachal-carcinoma</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Research-and-science/Microscope.webp?t=1588872688" type="image/png" medium="image" fileSize="408468">
        <media:title type="plain">Microscope</media:title>
      </media:content>
    </item>
    <item>
      <title>Tyra Biosciences’ TYRA-430 exerts antitumoral effects in HCC</title>
      <description>
        <![CDATA[Hepatocellular carcinoma (HCC) is an aggressive disease that accounts for 80%-90% of all primary liver cancers. Previous findings have shown fibroblast growth factor 19 (FGF-19) to be overexpressed in up to 30% of HCC cases, exerting its oncogenic effect through its receptors fibroblast growth factor receptor 3 (FGFR3) and FGFR4.]]>
      </description>
      <guid>http://www.bioworld.com/articles/717034</guid>
      <pubDate>Thu, 06 Feb 2025 09:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/717034-tyra-biosciences-tyra-430-exerts-antitumoral-effects-in-hcc</link>
    </item>
    <item>
      <title>Next-generation siRNA successfully silences multiple KRAS mutations </title>
      <description>
        <![CDATA[KRAS G12D and G12V mutations are highly prevalent in aggressive gastrointestinal tumor types such as pancreatic cancer.]]>
      </description>
      <guid>http://www.bioworld.com/articles/716855</guid>
      <pubDate>Tue, 04 Feb 2025 09:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/716855-next-generation-sirna-successfully-silences-multiple-kras-mutations</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/cancer-cell-light.webp?t=1683122726" type="image/jpeg" medium="image" fileSize="221907">
        <media:title type="plain">Cancer cells</media:title>
      </media:content>
    </item>
    <item>
      <title>AUS-001 shows antitumoral activity in pancreatic cancer</title>
      <description>
        <![CDATA[Pancreatic cancer is a challenge due to its poor prognosis and high mortality rate, highlighting the need for new therapeutic approaches. Previous findings have shown that AUS-001 inhibits β-tubulin polymerization through its unique binding to the tubulin’s colchicine site. ]]>
      </description>
      <guid>http://www.bioworld.com/articles/716664</guid>
      <pubDate>Tue, 28 Jan 2025 09:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/716664-aus-001-shows-antitumoral-activity-in-pancreatic-cancer</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Pancreatic-cancer.webp?t=1699369659" type="image/jpeg" medium="image" fileSize="252463">
        <media:title type="plain">Illustration of cancer tumor on pancreas</media:title>
      </media:content>
    </item>
    <item>
      <title>Plogosertib demonstrates efficacy in patient-derived models of colorectal cancer</title>
      <description>
        <![CDATA[At the recent ASCO Gastrointestinal Cancers symposium, Cyclacel Ltd. presented preclinical data for the Polo-like kinase 1 (PLK1) inhibitor plogosertib from assessment in models of colorectal cancer.]]>
      </description>
      <guid>http://www.bioworld.com/articles/716661</guid>
      <pubDate>Tue, 28 Jan 2025 09:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/716661-plogosertib-demonstrates-efficacy-in-patient-derived-models-of-colorectal-cancer</link>
    </item>
    <item>
      <title>SCD phase I/II death shines Beam on ‘very real’ busulfan risk</title>
      <description>
        <![CDATA[Alongside the release of abstracts related to the American Society of Hematology meeting next month in San Diego, and as part of the firm’s third-quarter update, Beam Therapeutics Inc. disclosed that one patient died in the phase I/II trial testing BEAM-101 in sickle cell disease (SCD).]]>
      </description>
      <guid>http://www.bioworld.com/articles/714196</guid>
      <pubDate>Tue, 05 Nov 2024 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/714196-scd-phase-i-ii-death-shines-beam-on-very-real-busulfan-risk</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Hematologic/Sickle-cell-red-blood-cells-SCD.webp?t=1723130326" type="image/jpeg" medium="image" fileSize="79838">
        <media:title type="plain">Illustration of sickle-cell and normal red blood cells</media:title>
      </media:content>
    </item>
    <item>
      <title>RGT-61159, an RNA-targeting small molecule with efficacy in cancer models driven by MYB dysregulation</title>
      <description>
        <![CDATA[Rgenta Therapeutics Inc. has presented their work on the discovery and development of RGT-61159, a potential first-in-class oral inhibitor of the oncogenic transcription factor c-MYB.]]>
      </description>
      <guid>http://www.bioworld.com/articles/709564</guid>
      <pubDate>Fri, 14 Jun 2024 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/709564-rgt-61159-an-rna-targeting-small-molecule-with-efficacy-in-cancer-models-driven-by-myb-dysregulation</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Ribosome-as-part-of-an-biological-cell-constructing-mRNA-molecules.webp?t=1708618722" type="image/jpeg" medium="image" fileSize="437349">
        <media:title type="plain">Ribosome as part of an biological cell constructing mRNA molecules</media:title>
      </media:content>
    </item>
    <item>
      <title>Nonclinical evidence supporting oncolytic virotherapy for multiple solid tumors</title>
      <description>
        <![CDATA[Calidi Biotherapeutics Inc. has conducted studies in animals to determine the safety and efficacy of oncolytic virotherapy (OV) with CLD-201 (Supernova-1) to treat solid tumors.]]>
      </description>
      <guid>http://www.bioworld.com/articles/709333</guid>
      <pubDate>Mon, 10 Jun 2024 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/709333-nonclinical-evidence-supporting-oncolytic-virotherapy-for-multiple-solid-tumors</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Cancer-oncolytic-virus.webp?t=1686582707" type="image/jpeg" medium="image" fileSize="306419">
        <media:title type="plain">Concept art for "cancer cells destroyed by oncogenic virus"</media:title>
      </media:content>
    </item>
    <item>
      <title>D0112-005, selective PARP-1 inhibitor with potent antitumor activity in BRCA-mutant models</title>
      <description>
        <![CDATA[Chengdu Easton Biopharmaceuticals Co. Ltd. recently presented findings that highlight the potential anticancer agent D0112-005 as a potent and selective poly (ADP-ribose) polymerase 1 (PARP-1) inhibitor with excellent antitumor efficacy and a good safety profile in vivo.]]>
      </description>
      <guid>http://www.bioworld.com/articles/709325</guid>
      <pubDate>Mon, 10 Jun 2024 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/709325-d0112-005-selective-parp-1-inhibitor-with-potent-antitumor-activity-in-brca-mutant-models</link>
    </item>
    <item>
      <title>Odimma’s anti-CTLA-4 biologic ODI-2001 shows promise for treating cancer</title>
      <description>
        <![CDATA[Odimma Therapeutics SAS has developed ODI-2001, a new biological from the combination of neoantigen-expressing DNA vector, an anti-CTLA-4 antibody and an attenuated poxvirus with the aim of increasing the immune response against tumors.]]>
      </description>
      <guid>http://www.bioworld.com/articles/709300</guid>
      <pubDate>Fri, 07 Jun 2024 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/709300-odimmas-anti-ctla-4-biologic-odi-2001-shows-promise-for-treating-cancer</link>
    </item>
    <item>
      <title>Developers hop to it, make TROP2 do it – some more than others</title>
      <description>
        <![CDATA[Trophoblast cell-surface antigen 2 (TROP2) antibody-drug conjugates became a topic of talk during the recent American Society of Clinical Oncology meeting in Chicago.]]>
      </description>
      <guid>http://www.bioworld.com/articles/709345</guid>
      <pubDate>Thu, 06 Jun 2024 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/709345-developers-hop-to-it-make-trop2-do-it-some-more-than-others</link>
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        <media:title type="plain">3D rendering of an antibody-drug conjugate</media:title>
      </media:content>
    </item>
    <item>
      <title>Hyperway’s KRAS G12D inhibitor demonstrates potent preclinical antitumor activity</title>
      <description>
        <![CDATA[KRAS is the most commonly mutated oncogene in solid tumors. Mutations are present in about 30% of cases overall, more than 95% of pancreatic cancer cases, and about 40% of colon cancer cases.]]>
      </description>
      <guid>http://www.bioworld.com/articles/709231</guid>
      <pubDate>Thu, 06 Jun 2024 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/709231-hyperways-kras-g12d-inhibitor-demonstrates-potent-preclinical-antitumor-activity</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Cancer-cell-and-target.webp?t=1703001756" type="image/jpeg" medium="image" fileSize="313981">
        <media:title type="plain">Cancer cell targeted in crosshairs</media:title>
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