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    <title>IDWeek</title>
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    <item>
      <title>Antifungal activity, reduced cytotoxicity with COT-832 in vitro and in vivo</title>
      <description>
        <![CDATA[Studies evaluating the in vitro and in vivo antifungal activity, hemolytic activity and cytotoxicity of COT-832, a novel polyene macrolide antifungal that is a chemical modification of amphotericin B (AmB), were presented at IDWeek by Shionogi & Co. Ltd.]]>
      </description>
      <guid>http://www.bioworld.com/articles/713672</guid>
      <pubDate>Wed, 23 Oct 2024 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/713672-antifungal-activity-reduced-cytotoxicity-with-cot-832-in-vitro-and-in-vivo</link>
    </item>
    <item>
      <title>Drug-Fc conjugate protects from seasonal and pandemic influenza strains</title>
      <description>
        <![CDATA[The influenza virus undergoes rapid and frequent antigen shifts that usually force seasonal vaccine updating. The mismatch between vaccine strains and circulating viruses leads to limited vaccine effectiveness, mainly in immunocompromised and older individuals.]]>
      </description>
      <guid>http://www.bioworld.com/articles/713645</guid>
      <pubDate>Tue, 22 Oct 2024 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/713645-drug-fc-conjugate-protects-from-seasonal-and-pandemic-influenza-strains</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Infectious/Influenza-virus-3d-illustration.webp?t=1713278290" type="image/jpeg" medium="image" fileSize="481671">
        <media:title type="plain">3D illustration showing surface glycoprotein spikes hemagglutinin (purple) and neuraminidase (orange)</media:title>
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    <item>
      <title>First-in-class antisense RNA therapy for BK virus presented </title>
      <description>
        <![CDATA[Patients receiving a kidney transplant and who are positive for BK virus (BKV) are at risk of losing their transplant due to BKV reactivation. At this time, there are no antiviral options available for the prevention of BKV-associated nephropathy. Researchers from Aicuris Anti-infective Cures GmbH presented preclinical data on AIC-468, an antisense RNA therapy that inhibits the splicing process of a viral mRNA encoding a protein critical for BKV replication.]]>
      </description>
      <guid>http://www.bioworld.com/articles/713641</guid>
      <pubDate>Tue, 22 Oct 2024 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/713641-first-in-class-antisense-rna-therapy-for-bk-virus-presented</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Nephrology/Neprology-healthy-kidneys.webp?t=1745263173" type="image/jpeg" medium="image" fileSize="175840">
        <media:title type="plain">Doctor with illustration of kidneys</media:title>
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    <item>
      <title>Merck’s clesrovimab tortoise to Beyfortus in RSV race?</title>
      <description>
        <![CDATA[Wall Street promptly began trying to weigh the compound’s marketplace odds after Merck & Co. Inc. detailed positive data from the phase IIb/III trial known as MK-1654-004 with clesrovimab, an investigational prophylactic monoclonal antibody designed to protect infants from respiratory syncytial virus (RSV) disease during their first RSV season. The results, plus interim findings from the ongoing phase III experiment dubbed MK-1654-007 were offered during IDWeek 2024 in Los Angeles.]]>
      </description>
      <guid>http://www.bioworld.com/articles/713635</guid>
      <pubDate>Fri, 18 Oct 2024 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/713635-mercks-clesrovimab-tortoise-to-beyfortus-in-rsv-race</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Pediatric/Baby-bandage.webp?t=1745266547" type="image/jpeg" medium="image" fileSize="188240">
        <media:title type="plain">Baby with bandage on thigh</media:title>
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    </item>
    <item>
      <title>Morpholino oligomers combat &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; lifestyle</title>
      <description>
        <![CDATA[At the IDWeek 2023 infectious disease conference, Rachelle Koch, a medical student from the University of Texas Southwestern Medical Center, presented the work done in David Greenberg’s Lab on a new strategy to tackle <em>Pseudomonas aeruginosa</em> infections using D-peptide-conjugated phosphorodiamidate morpholino oligomers (D-PPMOs). <em>P. aeruginosa</em> is an opportunistic pathogen showing a multidrug-resistance (MDR) pattern that is at the root of significant morbidity and mortality, especially in immunocompromised patients with severe chronic lung diseases such as cystic fibrosis.]]>
      </description>
      <guid>http://www.bioworld.com/articles/702376</guid>
      <pubDate>Tue, 31 Oct 2023 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/702376-morpholino-oligomers-combat-empseudomonas-aeruginosa-em-lifestyle</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/biofilm-bacteria-petri-dish.webp?t=1706230445" type="image/jpeg" medium="image" fileSize="618557">
        <media:title type="plain">Biofilm growing on a petri dish</media:title>
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    </item>
    <item>
      <title>IDWeek 2023: Infectious epiphenomena in the climate change era</title>
      <description>
        <![CDATA[During the IDWeek conference held in Boston earlier this month, presentations on Climate Change were spread throughout the program. Some talks were on the direct effects of weather on infectious agents. Others discussed what healthcare workers could do to mitigate the effects of climate change, from antibiotic stewardship to decarbonization of day to day operations.]]>
      </description>
      <guid>http://www.bioworld.com/articles/702358</guid>
      <pubDate>Mon, 30 Oct 2023 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/702358-idweek-2023-infectious-epiphenomena-in-the-climate-change-era</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Geographic-regions/digital-globe-world.webp?t=1639781799" type="image/png" medium="image" fileSize="282439">
        <media:title type="plain">World with digital overlay</media:title>
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    </item>
    <item>
      <title>Ligand-targeted immunotherapy demonstrates excellent antiviral activity in models of influenza infection</title>
      <description>
        <![CDATA[Researchers from Eradivir Inc. and affiliated organizations presented the discovery and preclinical evaluation of EV-21, a dual mechanism antiviral immunotherapy for the treatment of influenza infections. EV-21 was designed as a ligand-targeted drug conjugate, developed by linking the neuraminidase inhibitor zanamivir to two distinct haptens that bind to two different naturally occurring antibodies in humans. As a result, the candidate acts though a dual mechanism of action, which consists of potent recruitment of the human immune system to recognize and destroy free viruses and virus-infected cells.]]>
      </description>
      <guid>http://www.bioworld.com/articles/702115</guid>
      <pubDate>Mon, 23 Oct 2023 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/702115-ligand-targeted-immunotherapy-demonstrates-excellent-antiviral-activity-in-models-of-influenza-infection</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/H1N1-flu-NIAID.webp?t=1695224339" type="image/png" medium="image" fileSize="1727970">
        <media:title type="plain">Transmission electron micrograph of H1N1.</media:title>
        <media:description type="plain">H1N1 virus particles. Credit: National Institute of Allergy and Infectious Diseases, NIH

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    </item>
    <item>
      <title>Conference data for Nov. 8, 2022: AASLD</title>
      <description>
        <![CDATA[New and updated preclinical and clinical data presented by biopharma firms at the AASLD Liver Meeting, including: 89bio, Albireo, Ascentage, Gannex, Seal Rock, Vaccitech, Vir.]]>
      </description>
      <guid>http://www.bioworld.com/articles/691326</guid>
      <pubDate>Tue, 08 Nov 2022 11:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/691326-conference-data-for-nov-8-2022-aasld</link>
    </item>
    <item>
      <title>Conference data for Nov. 7, 2022: AASLD</title>
      <description>
        <![CDATA[New and updated preclinical and clinical data presented by biopharma firms at the AASLD Liver Meeting, including: Aligos, Asher, Assembly, Ocelot, Rivus, Terns.]]>
      </description>
      <guid>http://www.bioworld.com/articles/691281</guid>
      <pubDate>Mon, 07 Nov 2022 10:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/691281-conference-data-for-nov-7-2022-aasld</link>
    </item>
    <item>
      <title>Conference data for Oct. 24, 2022: IDWeek</title>
      <description>
        <![CDATA[New and updated preclinical and clinical data presented by biopharma firms at IDWeek, including: Basilea, F2G, Ferring, Merck, Scynexis, Seres, Veru.]]>
      </description>
      <guid>http://www.bioworld.com/articles/690929</guid>
      <pubDate>Mon, 24 Oct 2022 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/690929-conference-data-for-oct-24-2022-idweek</link>
    </item>
    <item>
      <title>Brii Bio shares interim data on antibody combination therapy for SARS-CoV-2</title>
      <description>
        <![CDATA[Brii Biosciences Ltd. shared interim data from a phase III trial of its neutralizing monoclonal antibody (mAb) combination therapy for SARS-CoV-2, BRII-196 and BRII-198, that showed a 78% reduction in the risk of hospitalization or death in patients receiving single dose of the cocktail.]]>
      </description>
      <guid>http://www.bioworld.com/articles/512285</guid>
      <pubDate>Tue, 12 Oct 2021 14:33:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/512285-brii-bio-shares-interim-data-on-antibody-combination-therapy-for-sars-cov-2</link>
    </item>
    <item>
      <title>Brii Bio shares interim data on antibody combination therapy for SARS-CoV-2</title>
      <description>
        <![CDATA[Brii Biosciences Ltd. shared interim data from a phase III trial of its neutralizing monoclonal antibody (mAb) combination therapy for SARS-CoV-2, BRII-196 and BRII-198, that showed a 78% reduction in the risk of hospitalization or death in patients receiving single dose of the cocktail.]]>
      </description>
      <guid>http://www.bioworld.com/articles/512123</guid>
      <pubDate>Wed, 06 Oct 2021 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/512123-brii-bio-shares-interim-data-on-antibody-combination-therapy-for-sars-cov-2</link>
    </item>
    <item>
      <title>Roche-Regeneron cocktail reduces viral load in hospitalized COVID-19 patients</title>
      <description>
        <![CDATA[New data on the COVID-19 antibody therapy Ronapreve (casirivimab + imdevimab), already used to treat non-hospitalized patients in multiple countries, could potentially support expanding its use to certain recently hospitalized patients with the disease. ]]>
      </description>
      <guid>http://www.bioworld.com/articles/511941</guid>
      <pubDate>Thu, 30 Sep 2021 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/511941-roche-regeneron-cocktail-reduces-viral-load-in-hospitalized-covid-19-patients</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/Vial-and-syringe-illustration.webp?t=1616697465" type="image/png" medium="image" fileSize="336717">
        <media:title type="plain">Vial and syringe</media:title>
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    </item>
    <item>
      <title>Conference data for Sept. 30, 2021: IDWeek</title>
      <description>
        <![CDATA[New and updated preclinical and clinical data presented by biopharma firms at IDWeek 2021, including: Allovir, Codagenix, Ferring, Humanigen, Iliad, Mycovia, Neoleukin, Peptilogics, Scynexis, Seqirus, Viiv.]]>
      </description>
      <guid>http://www.bioworld.com/articles/511911</guid>
      <pubDate>Thu, 30 Sep 2021 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/511911-conference-data-for-sept-30-2021-idweek</link>
    </item>
    <item>
      <title>Day Zero sees positive data with tech to diagnose superbug infections</title>
      <description>
        <![CDATA[Day Zero Diagnostics Inc. has reported that data presented at IDWeek highlighted the promise of the company&rsquo;s new class of diagnostics as it works toward its goal of detecting superbug infections quickly. The company ultimately is hoping to get regulatory signoffs in both the U.S. and Europe for its technology.]]>
      </description>
      <guid>http://www.bioworld.com/articles/499420</guid>
      <pubDate>Mon, 26 Oct 2020 13:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/499420-day-zero-sees-positive-data-with-tech-to-diagnose-superbug-infections</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/drugs-antibiotics-AMR.webp?t=1588362842" type="image/png" medium="image" fileSize="250188">
        <media:title type="plain">Bacteria punching antibiotic capsule</media:title>
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    <item>
      <title>Despite 'existential crisis' in antibiotic development, hope persists, experts say</title>
      <description>
        <![CDATA[WASHINGTON – In case any question remained about who shoulders the blame for the serious lack of viable innovation in the infectious disease specialty, a panel at the Infectious Disease Society of America's IDWeek 2019 came with a surprisingly accusatory subtitle: "How ID Killed Antibiotic Development." Observing what Vivo Capital Managing Partner Chen Yu called "an existential crisis for the specialty," the session served as a call for action for infectious disease (ID) doctors to take control of prescribing, put patient care ahead of cost management, and advocate for both faster changes to clinical guidelines and legislative improvements to better position the industry.]]>
      </description>
      <guid>http://www.bioworld.com/articles/429712</guid>
      <pubDate>Fri, 04 Oct 2019 00:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/429712-despite-existential-crisis-in-antibiotic-development-hope-persists-experts-say</link>
    </item>
    <item>
      <title>Merck's Recarbrio, Shionogi's cefiderocol tackle bacterial pneumonia in phase III studies</title>
      <description>
        <![CDATA[WASHINGTON – Hot on the heels of July's FDA approval of Recarbrio (imipenem, cilastatin and relebactam) in complicated urinary tract infections (cUTIs), Merck & Co. Inc. rolled out pivotal phase III data at the Infectious Disease Society of America's IDWeek 2019 that could support expanding its label to another high-need group, people with hospital-acquired or ventilator-associated bacterial pneumonia (HABP/VABP). Shionogi & Co. Ltd., which is advancing its investigational antibiotic, cefiderocol, in the same indications, also shared new phase III data supporting its use in the high-risk population.]]>
      </description>
      <guid>http://www.bioworld.com/articles/429591</guid>
      <pubDate>Thu, 03 Oct 2019 00:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/429591-mercks-recarbrio-shionogis-cefiderocol-tackle-bacterial-pneumonia-in-phase-iii-studies</link>
    </item>
    <item>
      <title>Restorbio burnishes case for TORC1 inhibitor as it heads into phase III</title>
      <description>
        <![CDATA[WASHINGTON – A little more than a year after first reporting phase IIb results showing oral TORC1 inhibitor RTB-101 reduced the number of respiratory tract infections (RTIs) in older adults, Restorbio Inc. is illuminating what may be the mechanism behind its efficacy: the up-regulation of innate antiviral immunity. The data, presented at the Infectious Disease Society of America's IDWeek 2019, put the company on track to move into two phase III data readouts next year. ]]>
      </description>
      <guid>http://www.bioworld.com/articles/429592</guid>
      <pubDate>Thu, 03 Oct 2019 00:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/429592-restorbio-burnishes-case-for-torc1-inhibitor-as-it-heads-into-phase-iii</link>
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