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    <title>Neurology/psychiatric</title>
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    <item>
      <title>Abbvie nabs two Nav1.8 pain projects from Haisco in $745M deal </title>
      <description>
        <![CDATA[Abbvie Inc. is buying exclusive rights to develop, manufacture and commercialize two Nav1.8 inhibitors for pain – HSK-55718 and HSK-51155 – from Haisco Pharmaceutical Group Co. Ltd. for $30 million up front and up to $715 million in milestone payments, plus royalties.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730297</guid>
      <pubDate>Tue, 14 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730297-abbvie-nabs-two-nav18-pain-projects-from-haisco-in-745m-deal</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Pain-med-illustration2.webp?t=1776187647" type="image/jpeg" medium="image" fileSize="427247">
        <media:title type="plain">Open capsule delivering pain relief to body</media:title>
      </media:content>
    </item>
    <item>
      <title>Researchers unveil REDD1 as target for major depression</title>
      <description>
        <![CDATA[Investigators have shown that REED1 expression was elevated during stress, which in turn suppressed hippocampal synaptogenesis and induced major depressive disorder (MDD)-like behavior through mTORC1 signaling. The impact of REDD1 modulation was investigated in the preclinical setting for MDD.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730350</guid>
      <pubDate>Tue, 14 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730350-researchers-unveil-redd1-as-target-for-major-depression</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Depression-illustration1.webp?t=1667507237" type="image/png" medium="image" fileSize="213888">
        <media:title type="plain">Man sitting on bed holding head</media:title>
      </media:content>
    </item>
    <item>
      <title>Investment to advance Quiver’s ASO for Dup15q syndrome</title>
      <description>
        <![CDATA[Quiver Bioscience Inc. has received a strategic investment from the Porta family office (Argentina) to advance the company’s antisense oligonucleotide (ASO) therapeutic program for chromosome 15q duplication (Dup15q) syndrome. The investment will fund preclinical activities, including safety studies for candidate selection as the program advances toward clinical development.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730349</guid>
      <pubDate>Tue, 14 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730349-investment-to-advance-quivers-aso-for-dup15q-syndrome</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Brain-DNA.webp?t=1728053898" type="image/jpeg" medium="image" fileSize="371570">
        <media:title type="plain">Illustration of human brain and dna</media:title>
      </media:content>
    </item>
    <item>
      <title>Novel caspase-2 inhibitor shows in vivo neuroprotective effects</title>
      <description>
        <![CDATA[Caspase-2-mediated cleavage of tau at Asp314 generates a neurotoxic fragment, Δtau314, that drives early synaptic dysfunction in Alzheimer’s disease (AD) and frontotemporal dementia (FTD). This fragment accumulates at synapses, disrupts glutamatergic signaling and contributes to cognitive impairment in vivo.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730346</guid>
      <pubDate>Tue, 14 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730346-novel-caspase-2-inhibitor-shows-in-vivo-neuroprotective-effects</link>
    </item>
    <item>
      <title>Abbvie licenses ex-China rights to Haisco pain compounds</title>
      <description>
        <![CDATA[Haisco Pharmaceutical Group Co. Ltd. has entered into an exclusive licensing agreement with Abbvie Inc., granting Abbvie the exclusive rights to develop, manufacture and commercialize novel medicines for the treatment of pain globally, excluding mainland China, Hong Kong and Macau.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730326</guid>
      <pubDate>Mon, 13 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730326-abbvie-licenses-ex-china-rights-to-haisco-pain-compounds</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Neurology-nerve-cell-pain.webp?t=1682600134" type="image/jpeg" medium="image" fileSize="413083">
        <media:title type="plain">3D illustration of a nerve cell</media:title>
      </media:content>
    </item>
    <item>
      <title>Realta secures another $40M for its hypoxic ischemic encephalopathy treatment</title>
      <description>
        <![CDATA[Realta Life Sciences Inc. raised an additional $40 million in the final tranche of its series A investment, bringing the total the company has raised to more than $150 million through mission-driven investors and a family-office model.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730228</guid>
      <pubDate>Fri, 10 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730228-realta-secures-another-40m-for-its-hypoxic-ischemic-encephalopathy-treatment</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Pediatric/newborn-baby-infant.webp?t=1720795419" type="image/jpeg" medium="image" fileSize="169571">
        <media:title type="plain">Photo of hands holding a baby </media:title>
      </media:content>
    </item>
    <item>
      <title>PMP22-RNAi gives long-lasting protection in Charcot-Marie-Tooth</title>
      <description>
        <![CDATA[Researchers from the Cyprus Institute of Neurology and Genetics and collaborators report the development of a gene silencing therapy for <span style=" font-style: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; widows: 2; word-spacing: 0px; display: inline !important; float: none;">Charcot-Marie-Tooth type 1A</span>.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730260</guid>
      <pubDate>Fri, 10 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730260-pmp22-rnai-gives-long-lasting-protection-in-charcot-marie-tooth</link>
    </item>
    <item>
      <title>MSD discloses new HCN1/2 blockers</title>
      <description>
        <![CDATA[Merck Sharp & Dohme LLC (MSD) has synthesized new indazole derivatives acting as potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1) and HCN2 blockers potentially useful for the treatment of pain, tinnitus, neurological and mood disorders.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730252</guid>
      <pubDate>Thu, 09 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730252-msd-discloses-new-hcn1-2-blockers</link>
    </item>
    <item>
      <title>Sononeu wins $5.2M ARPA-H grant for ultrasound-activated therapeutics</title>
      <description>
        <![CDATA[Newco Sononeu Inc. has launched to translate more than a decade of basic research in controlling cells with ultrasound into novel, non-invasive therapies for conditions including peripheral and diabetic neuropathy. The underlying technology of sonogenetics provides the ability to manipulate cellular activity via ultrasound-sensitive ion channels that respond to acoustic pressure. These channels may be endogenous, or could be delivered by targeted vectors to specific cell types.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730256</guid>
      <pubDate>Wed, 08 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730256-sononeu-wins-52m-arpa-h-grant-for-ultrasound-activated-therapeutics</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Foot-neuropathy-illustration.webp?t=1775587782" type="image/jpeg" medium="image" fileSize="740144">
        <media:title type="plain">Neuropathy illustrated in legs and feet</media:title>
      </media:content>
    </item>
    <item>
      <title>MMP inhibitors divulged in Accure Therapeutics patent</title>
      <description>
        <![CDATA[Accure Therapeutics has reported new oligopeptide derivatives acting as matrix metalloproteinase-2 (MMP-2) and MMP-9 inhibitors. As such, they are described as potentially useful for the treatment of epilepsy, schizophrenia, autism, cancer, mood disorder, sepsis, Alzheimer’s disease and vascular disorders, among others.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730200</guid>
      <pubDate>Wed, 08 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730200-mmp-inhibitors-divulged-in-accure-therapeutics-patent</link>
    </item>
    <item>
      <title>Sononeu wins $5.2M ARPA-H grant for ultrasound-activated therapeutics</title>
      <description>
        <![CDATA[Newco Sononeu Inc. has launched to translate more than a decade of basic research in controlling cells with ultrasound into novel, non-invasive therapies for conditions including peripheral and diabetic neuropathy.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730136</guid>
      <pubDate>Tue, 07 Apr 2026 11:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730136-sononeu-wins-52m-arpa-h-grant-for-ultrasound-activated-therapeutics</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Foot-neuropathy-illustration.webp?t=1775587782" type="image/jpeg" medium="image" fileSize="740144">
        <media:title type="plain">Neuropathy illustrated in legs and feet</media:title>
      </media:content>
    </item>
    <item>
      <title>Orexin OX2 receptor agonists disclosed in Vertex Pharmaceuticals patent</title>
      <description>
        <![CDATA[Vertex Pharmaceuticals Inc. has patented new macrocyclic sulfonamide orexin OX2 receptor agonists potentially useful for the treatment of amyotrophic lateral sclerosis, obesity, hypertension, retinopathy, multiple sclerosis, narcolepsy, hypersomnia and Parkinson's disease, among others.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730176</guid>
      <pubDate>Tue, 07 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730176-orexin-ox2-receptor-agonists-disclosed-in-vertex-pharmaceuticals-patent</link>
    </item>
    <item>
      <title>Acadia Pharmaceuticals presents GPR88 agonists</title>
      <description>
        <![CDATA[Acadia Pharmaceuticals Inc. has reported new G protein-coupled receptor GPR88 agonists that are potentially useful for the treatment of tardive dyskinesia.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730175</guid>
      <pubDate>Tue, 07 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730175-acadia-pharmaceuticals-presents-gpr88-agonists</link>
    </item>
    <item>
      <title>Optimization of brain-permeable SGK1 inhibitors for neurodegenerative diseases</title>
      <description>
        <![CDATA[Kinase inhibitors have shown success in disease areas such as oncology, but their application in neurodegenerative diseases is still limited. This is mainly due to several challenges, such as the complexity of kinase networks, limited blood-brain barrier permeability and the lack of biomarkers.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730170</guid>
      <pubDate>Tue, 07 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730170-optimization-of-brain-permeable-sgk1-inhibitors-for-neurodegenerative-diseases</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/neurology-dementia-alzheimers.webp?t=1588366730" type="image/png" medium="image" fileSize="529008">
        <media:title type="plain">Man piecing together a puzzle</media:title>
      </media:content>
    </item>
    <item>
      <title>Oral ‘roid void in PPD? Lipocine MINI bike may have wheels</title>
      <description>
        <![CDATA[Hopes in postpartum depression (PPD) with an oral version of brexanolone – a synthetic formulation of the endogenous neurosteroid allopregnanolone, approved by the U.S. FDA in 2019 when given intravenously for PPD – were dashed, at least near term, when Lipocine Inc. reported that the candidate failed in a phase III placebo-controlled trial.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730072</guid>
      <pubDate>Thu, 02 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730072-oral-roid-void-in-ppd-lipocine-mini-bike-may-have-wheels</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Postpartum-depression-mother-baby.webp?t=1745264208" type="image/jpeg" medium="image" fileSize="145014">
        <media:title type="plain">Tired mother holding newborn</media:title>
      </media:content>
    </item>
    <item>
      <title>Korsana boosts Alzheimer’s work with reverse merger, $380M financing</title>
      <description>
        <![CDATA[Just over a month after emerging from stealth and disclosing a $150 million series A, Korsana Biosciences Inc. is making the leap to the public market via a merger with Cyclerion Therapeutics Inc. &nbsp;The agreement, which is backed by a $370 million private placement from Korsana’s investors, solidly positions the newly merged company as it heads toward the clinic with KRSA-028, a next-generation shuttled antibody targeting amyloid beta for the treatment of Alzheimer’s disease, and builds out a pipeline of neurodegenerative disease candidates.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730126</guid>
      <pubDate>Thu, 02 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730126-korsana-boosts-alzheimers-work-with-reverse-merger-380m-financing</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Deals-and-MAs/Deal-puzzle-pieces.webp?t=1588276668" type="image/png" medium="image" fileSize="174585">
        <media:title type="plain">Connecting puzzle pieces</media:title>
      </media:content>
    </item>
    <item>
      <title>Hengrui discovers new Nav1.8 blockers</title>
      <description>
        <![CDATA[Researchers from Jiangsu Hengrui Pharmaceuticals Co. Ltd. and Shanghai Hengrui Pharmaceutical Co. Ltd. have patented new sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers that are potentially useful for the treatment of pain, urinary incontinence, multiple sclerosis, cough and arrhythmia.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730105</guid>
      <pubDate>Thu, 02 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730105-hengrui-discovers-new-nav18-blockers</link>
    </item>
    <item>
      <title>Korsana boosts Alzheimer’s work with reverse merger, $380M financing</title>
      <description>
        <![CDATA[Just over a month after emerging from stealth and disclosing a $150 million series A, Korsana Biosciences Inc. is making the leap to the public market via a merger with Cyclerion Therapeutics Inc. &nbsp;The agreement, which is backed by a $370 million private placement from Korsana’s investors, solidly positions the newly merged company as it heads toward the clinic with KRSA-028, a next-generation shuttled antibody targeting amyloid beta for the treatment of Alzheimer’s disease, and builds out a pipeline of neurodegenerative disease candidates.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729977</guid>
      <pubDate>Wed, 01 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729977-korsana-boosts-alzheimers-work-with-reverse-merger-380m-financing</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Deals-and-MAs/Deal-puzzle-pieces.webp?t=1588276668" type="image/png" medium="image" fileSize="174585">
        <media:title type="plain">Connecting puzzle pieces</media:title>
      </media:content>
    </item>
    <item>
      <title>CRISPR-mediated utrophin upregulation preclinically improves DMD</title>
      <description>
        <![CDATA[Currently available disease management options for Duchenne muscular dystrophy (DMD) are mostly symptomatic. Several strategies based on exon-skipping or gene transfer have been proposed to restore dystrophin expression, but can only address specific subsets of DMD patients and/or provide limited clinical benefits. Upregulating utrophin (UTRN), a structural and functional paralogue of dystrophin, has been proposed as an alternative therapeutic approach that may be suitable for all DMD patients, regardless of their genetic defect.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730056</guid>
      <pubDate>Wed, 01 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730056-crispr-mediated-utrophin-upregulation-preclinically-improves-dmd</link>
    </item>
    <item>
      <title>Otsuka to acquire PTSD drugmaker Transcend in $1.2B deal </title>
      <description>
        <![CDATA[Otsuka Pharmaceutical Co. Ltd. is taking a neuroplastogen approach to posttraumatic stress disorder (PTSD) through its planned $1.22 billion acquisition of Transcend Therapeutics Inc. The deal gives Tokyo-headquartered Otsuka access to Transcend’s lead asset, TSND-201, an oral neuroplastogen that has begun patient recruitment for a phase III study in the U.S.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730090</guid>
      <pubDate>Tue, 31 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730090-otsuka-to-acquire-ptsd-drugmaker-transcend-in-12b-deal</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Deals-and-MAs/Brain-with-handshake-and-cityscape.webp?t=1609792702" type="image/png" medium="image" fileSize="549630">
        <media:title type="plain">Brain with handshake and cityscape</media:title>
      </media:content>
    </item>
    <item>
      <title>Lilly shifts from obesity to narcolepsy with $7.8B Centessa buy</title>
      <description>
        <![CDATA[Eli Lilly and Co. plans to buy Centessa Pharmaceuticals plc for $6.3 billion in up-front cash and another potential $1.5 billion through contingent value rights, gaining access to a pipeline of orexin receptor 2 agonists for sleep disorders. The Indianapolis-based pharma is re-entering a field that has multibillion-dollar potential and one that could emulate the success seen with its obesity program. Centessa, of Boston and London, has a lead candidate, cleminorexton (formerly ORX-750), with positive phase IIa data in narcolepsy types 1 and 2 and idiopathic hypersomnia.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729962</guid>
      <pubDate>Tue, 31 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729962-lilly-shifts-from-obesity-to-narcolepsy-with-78b-centessa-buy</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Circadian-Brain-Clock.webp?t=1674747494" type="image/png" medium="image" fileSize="1412196">
        <media:title type="plain">Brain with clock hands, day and night background </media:title>
      </media:content>
    </item>
    <item>
      <title>Montclair State, University of Maryland identify PDE11A4 inhibitors</title>
      <description>
        <![CDATA[Montclair State University and the University of Maryland have discovered new dual 3’,5’-cyclic-AMP and -GMP phosphodiesterase 11A4 (PDE11A4) inhibitors potentially useful for the treatment of cognitive disorders.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730051</guid>
      <pubDate>Tue, 31 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730051-montclair-state-university-of-maryland-identify-pde11a4-inhibitors</link>
    </item>
    <item>
      <title>Funding to advance Marvel’s MB-204 into clinic</title>
      <description>
        <![CDATA[Marvel Biosciences Corp., together with its wholly owned subsidiary Marvel Biotechnology Inc., has announced nondilutive funding from the Alberta Innovates CarE (AICE) market access program to support progression into the clinic and phase I testing of lead compound, MB-204. MB-204, a fluorinated derivative version of istradefylline, offers potential as a new approach totreating autism spectrum disorders and related conditions, addressing socio-behavioral symptoms through a differentiated mechanism.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730038</guid>
      <pubDate>Tue, 31 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730038-funding-to-advance-marvels-mb-204-into-clinic</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Brain-with-puzzle-piece-removed.webp?t=1595012724" type="image/png" medium="image" fileSize="452654">
        <media:title type="plain">Brain with puzzle piece removed</media:title>
      </media:content>
    </item>
    <item>
      <title>Antitumoral antibodies cross the BBB and alter brain signaling</title>
      <description>
        <![CDATA[Certain cancers, such as triple-negative breast cancer, produce antibodies that, although they help fight the tumor, can cross the blood-brain barrier and alter the function of NMDA receptors (NMDAR) in the brain, which are essential for neuronal signaling. Scientists at Cold Spring Harbor Laboratory (CSHL) have identified their origin and described how this process is linked to the maturation of these antibodies, which can activate or inhibit the receptor, causing neurological and psychiatric symptoms.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730035</guid>
      <pubDate>Tue, 31 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730035-antitumoral-antibodies-cross-the-bbb-and-alter-brain-signaling</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Neurology-immune-neuron-antibodies.webp?t=1774968985" type="image/jpeg" medium="image" fileSize="356156">
        <media:title type="plain">Antibodies and synaptic neuron</media:title>
      </media:content>
    </item>
    <item>
      <title>Otsuka to acquire PTSD drugmaker Transcend in $1.2B deal </title>
      <description>
        <![CDATA[Otsuka Pharmaceutical Co. Ltd. is taking a neuroplastogen approach to posttraumatic stress disorder (PTSD) through its planned $1.22 billion acquisition of Transcend Therapeutics Inc. The deal gives Tokyo-headquartered Otsuka access to Transcend’s lead asset, TSND-201, an oral neuroplastogen that has begun patient recruitment for a phase III study in the U.S.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729952</guid>
      <pubDate>Mon, 30 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729952-otsuka-to-acquire-ptsd-drugmaker-transcend-in-12b-deal</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Deals-and-MAs/Brain-with-handshake-and-cityscape.webp?t=1609792702" type="image/png" medium="image" fileSize="549630">
        <media:title type="plain">Brain with handshake and cityscape</media:title>
      </media:content>
    </item>
    <item>
      <title>Targeting PGAM5 slows down ALS progression</title>
      <description>
        <![CDATA[Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle wasting and paralysis, among others. Due to its high clinical heterogeneity, effective therapies are still not available.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730017</guid>
      <pubDate>Mon, 30 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730017-targeting-pgam5-slows-down-als-progression</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/ALS-amyotrophic-lateral-sclerosis.webp?t=1668098890" type="image/png" medium="image" fileSize="439388">
        <media:title type="plain">Illustration demonstrating muscle contraction in amyotrophic lateral sclerosis.</media:title>
      </media:content>
    </item>
    <item>
      <title>Molecular signatures show subtypes in neurodegenerative diseases</title>
      <description>
        <![CDATA[Parkinson’s disease is a progressive neurodegenerative disorder best known for its motor symptoms. However, a proportion of patients also develop dementia as the condition advances. Yet the biological divide between those who experience this cognitive decline and those who do not has remained an open question. Are they different conditions or simply stages of the same disease?]]>
      </description>
      <guid>http://www.bioworld.com/articles/730013</guid>
      <pubDate>Mon, 30 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730013-molecular-signatures-show-subtypes-in-neurodegenerative-diseases</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Neuron-nerve-cell-dna-genetics.webp?t=1774882830" type="image/jpeg" medium="image" fileSize="414335">
        <media:title type="plain">Illustration of a nerve cell with DNA double helix</media:title>
      </media:content>
    </item>
    <item>
      <title>Small-molecule TREM2 agonist advances to treat Alzheimer’s</title>
      <description>
        <![CDATA[Microglia play a central role in the neuroinflammation associated with Alzheimer’s disease (AD). At the 20th International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD), scientists focused on TREM2, a microglial receptor that regulates immune responses, exploring new ways to address neuroinflammation.&nbsp;]]>
      </description>
      <guid>http://www.bioworld.com/articles/730054</guid>
      <pubDate>Fri, 27 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730054-small-molecule-trem2-agonist-advances-to-treat-alzheimers</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Alzheimers-disease-vs-healthy-brain-neurons.webp?t=1774539087" type="image/jpeg" medium="image" fileSize="461468">
        <media:title type="plain">Comparison of neurons in a healthy brain and nerve cells in neurodegenerative disease with amyloid plaques</media:title>
      </media:content>
    </item>
    <item>
      <title>Xcath sees Iris robotic platform transforming stroke treatment</title>
      <description>
        <![CDATA[As robotic-assisted surgery platforms increasingly demonstrate that they can perform telesurgery safely, the question now is how soon remote operations will become part of routine clinical care. Eduardo Fonseca, CEO of Xcath Robotics Inc., reckons that within a decade the company’s Iris Surgical Robotic System could be in widespread use.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729916</guid>
      <pubDate>Fri, 27 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729916-xcath-sees-iris-robotic-platform-transforming-stroke-treatment</link>
      <media:content url="https://www.bioworld.com/ext/resources/BW-source/2026/XCath-telesurgery-hero-3-27-26.webp?t=1774644243" type="image/jpeg" medium="image" fileSize="706985">
        <media:title type="plain">Xcath Team Santiago Control Room</media:title>
        <media:description type="plain">Neurosurgeon Dr. Vitor Mendes Pereira controlling the telesurgery system and Dr. Fred Moll, chairman of Xcath, in the Santiago control room. Credit: Xcath Robotics Inc.
</media:description>
      </media:content>
    </item>
    <item>
      <title>Atai Therapeutics patents new 5-HT2 receptor agonists</title>
      <description>
        <![CDATA[Atai Therapeutics Inc. has identified new 5-HT2 receptor agonists potentially useful for the treatment of psychiatric disorders.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729940</guid>
      <pubDate>Thu, 26 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729940-atai-therapeutics-patents-new-5-ht2-receptor-agonists</link>
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