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    <title>Obesity</title>
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    <item>
      <title>CMS to Bridge coverage for obesity drugs as BALANCE teeters</title>
      <description>
        <![CDATA[When the U.S. CMS didn’t get takers for its voluntary Better Approaches to Lifestyle and Nutrition for Comprehensive Health (BALANCE) model to cover obesity drugs under Medicare Part D, the agency punted. It announced late April 21 that it will indefinitely delay the BALANCE model in Medicare but extend its temporary Medicare GLP-1 Bridge demonstration model through the end of 2027. (The Medicaid BALANCE model will still kick in this year in states that choose to participate in it.)]]>
      </description>
      <guid>http://www.bioworld.com/articles/730497</guid>
      <pubDate>Wed, 22 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730497-cms-to-bridge-coverage-for-obesity-drugs-as-balance-teeters</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/Generic-injection-pens.webp?t=1725043126" type="image/jpeg" medium="image" fileSize="126406">
        <media:title type="plain">Generic injection pens</media:title>
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    <item>
      <title>Obesity-focused Kailera goes for US biopharma record with $625M IPO</title>
      <description>
        <![CDATA[Kailera Therapeutics Inc.’s “obesity-first” approach continues to resonate with investors, with the company pricing an upsized IPO, offering 39 million shares at $16 apiece for gross proceeds of $625 million. Full exercise of the underwriters’ option could add another $93.8 million, bringing the total to nearly $719 million, easily topping Sana Biotechnology Inc.’s $675.6 million 2021 IPO and setting a new record for U.S. biopharma IPOs, according to <em>BioWorld</em> data.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730403</guid>
      <pubDate>Fri, 17 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730403-obesity-focused-kailera-goes-for-us-biopharma-record-with-625m-ipo</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Money/Gold-IPO-with-chart.webp?t=1776456932" type="image/jpeg" medium="image" fileSize="507410">
        <media:title type="plain">Gold IPO with chart</media:title>
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    <item>
      <title>Lilly’s GLP-1 Foundayo aces MACE in DILI of a phase III </title>
      <description>
        <![CDATA[Wall Street met with satisfaction but not surprise Eli Lilly and Co.’s undeniably positive top-line results from the phase III Achieve-4 study testing the efficacy and safety of Foundayo (orforglipron) compared to insulin glargine in adults with type 2 diabetes and obesity or overweight at increased cardiovascular risk.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730389</guid>
      <pubDate>Thu, 16 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730389-lillys-glp-1-foundayo-aces-mace-in-dili-of-a-phase-iii</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/Foundayo.webp?t=1776371156" type="image/jpeg" medium="image" fileSize="145217">
        <media:title type="plain">Foundayo</media:title>
        <media:description type="plain">Credit: Eli Lilly and Co.</media:description>
      </media:content>
    </item>
    <item>
      <title>In the mix post-Ventyx, more NLRP3s to seize?  </title>
      <description>
        <![CDATA[Eli Lilly and Co.’s buyout of Ventyx Biosciences Inc. for $1.2 billion at the start of the year brought to the forefront NLR family pyrin domain containing 3 (NLRP3) inhibitors, on which a handful of developers have been working – and research in the space continues to roll out, as with the paper published March 26 in <em>Nature</em> that delved into mechanisms that rev up the NLRP3 inflammasome.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730313</guid>
      <pubDate>Wed, 15 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730313-in-the-mix-post-ventyx-more-nlrp3s-to-seize</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/NLRP3-inflammasome.webp?t=1687271826" type="image/jpeg" medium="image" fileSize="295477">
        <media:title type="plain">NLRP3 inflammasome</media:title>
      </media:content>
    </item>
    <item>
      <title>Biologics in development outnumber small molecules for the first time</title>
      <description>
        <![CDATA[More than four decades on from the approval of the first biologic drug, the industry has reached a tipping point, and biotech drugs now outnumber small molecules in the global R&D pipeline.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730418</guid>
      <pubDate>Tue, 14 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730418-biologics-in-development-outnumber-small-molecules-for-the-first-time</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Research-and-science/Drug-research-illustration1.webp?t=1600982220" type="image/png" medium="image" fileSize="443224">
        <media:title type="plain">Drug research illustration</media:title>
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      <title>Fit and fat: Study shows no such thing as metabolically healthy obesity</title>
      <description>
        <![CDATA[There are new data to chew over in the ongoing controversy about obesity being diagnosed as a disease from a study tracking 157,159 participants in the UK Biobank over 13 years. This shows that even in the absence of any metabolic disturbance such as elevated lipids, high blood pressure or diabetes, there is an increased risk of heart attack, stroke, peripheral arterial disease, heart failure and liver disease in people with a body mass index over 30.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730369</guid>
      <pubDate>Mon, 13 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730369-fit-and-fat-study-shows-no-such-thing-as-metabolically-healthy-obesity</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Obesity/Woman-exercising-with-hand-weights.webp?t=1775851436" type="image/jpeg" medium="image" fileSize="559918">
        <media:title type="plain">Woman exercising with hand weights</media:title>
      </media:content>
    </item>
    <item>
      <title>Fit and fat: Study shows no such thing as metabolically healthy obesity</title>
      <description>
        <![CDATA[There are new data to chew over in the ongoing controversy about obesity being diagnosed as a disease from a study tracking 157,159 participants in the UK Biobank over 13 years. This shows that even in the absence of any metabolic disturbance such as elevated lipids, high blood pressure or diabetes, there is an increased risk of heart attack, stroke, peripheral arterial disease, heart failure and liver disease in people with a body mass index over 30.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730222</guid>
      <pubDate>Fri, 10 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730222-fit-and-fat-study-shows-no-such-thing-as-metabolically-healthy-obesity</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Obesity/Woman-exercising-with-hand-weights.webp?t=1775851436" type="image/jpeg" medium="image" fileSize="559918">
        <media:title type="plain">Woman exercising with hand weights</media:title>
      </media:content>
    </item>
    <item>
      <title>Biologics in development outnumber small molecules for the first time</title>
      <description>
        <![CDATA[More than four decades on from the approval of the first biologic drug, the industry has reached a tipping point, and biotech drugs now outnumber small molecules in the global R&D pipeline. At the start of the biotech industry, progress was slow. Between 1983 and 1995, the U.S. FDA approved an average of two biologics each year. Now, biologics have taken the lead by the smallest of margins, accounting for 50.1% of drugs in development at the start of 2026, according to the <em>Pharma Annual Review 2026</em>, published by Pharmaprojects, a firm that tracks global pharma R&D.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730343</guid>
      <pubDate>Fri, 10 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730343-biologics-in-development-outnumber-small-molecules-for-the-first-time</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Research-and-science/Drug-research-illustration1.webp?t=1600982220" type="image/png" medium="image" fileSize="443224">
        <media:title type="plain">Drug research illustration</media:title>
      </media:content>
    </item>
    <item>
      <title>Biologics in development outnumber small molecules for the first time</title>
      <description>
        <![CDATA[More than four decades on from the approval of the first biologic drug, the industry has reached a tipping point, and biotech drugs now outnumber small molecules in the global R&D pipeline.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730211</guid>
      <pubDate>Thu, 09 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730211-biologics-in-development-outnumber-small-molecules-for-the-first-time</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Research-and-science/Drug-research-illustration1.webp?t=1600982220" type="image/png" medium="image" fileSize="443224">
        <media:title type="plain">Drug research illustration</media:title>
      </media:content>
    </item>
    <item>
      <title>Ambrosia slurps up a $100M series B for its oral obesity drug pipeline</title>
      <description>
        <![CDATA[Ambrosia Biosciences Inc., named after the drink of the Greek gods, secured a $100 million series B to advance its preclinical pipeline of oral obesity drugs. The startup formed after Pfizer Inc. shuttered its Boulder, Colo.-based research facility that the pharma gained through its 2019 acquisition of Array Biopharma Inc.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730076</guid>
      <pubDate>Thu, 02 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730076-ambrosia-slurps-up-a-100m-series-b-for-its-oral-obesity-drug-pipeline</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Obesity/Pills-bottle-scale-and-measuring-tape.webp?t=1704492123" type="image/jpeg" medium="image" fileSize="266968">
        <media:title type="plain">Pills, bottle, scale and-measuring tape</media:title>
      </media:content>
    </item>
    <item>
      <title>Lilly’s Foundayo enters oral GLP-1 obesity market with speedy FDA nod</title>
      <description>
        <![CDATA[Eli Lilly and Co. anticipates shipping newly approved Foundayo (orforglipron) within the next week, as the drug becomes the second oral weight-loss glucagon-like peptide-1 (GLP-1) receptor agonist to enter the U.S. market following December’s approval of Novo Nordisk A/S’ Wegovy (semaglutide) pill.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729976</guid>
      <pubDate>Wed, 01 Apr 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729976-lillys-foundayo-enters-oral-glp-1-obesity-market-with-speedy-fda-nod</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Misc/Eli-Lilly-signage.webp?t=1767910760" type="image/jpeg" medium="image" fileSize="673005">
        <media:title type="plain">Eli Lilly logo atop Lilly Biotechnology Center campus in San Diego, Calif.</media:title>
        <media:description type="plain">Credit: MichaelVi - stock.adobe.com</media:description>
      </media:content>
    </item>
    <item>
      <title>China-developed triple incretin enters global diabetes race</title>
      <description>
        <![CDATA[A next-generation triple incretin therapy jointly developed by Novo Nordisk A/S and China’s United Biotechnology outperformed semaglutide in a phase II trial, signaling intensifying competition in the GLP-1 obesity and diabetes market.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730088</guid>
      <pubDate>Tue, 31 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730088-china-developed-triple-incretin-enters-global-diabetes-race</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Endocrine-Metabolic-glucose-bloodstream.webp?t=1674056639" type="image/png" medium="image" fileSize="1313266">
        <media:title type="plain">Illustration of glucose molecules in a bloodstream</media:title>
      </media:content>
    </item>
    <item>
      <title>US FDA pondering next steps for CNPV</title>
      <description>
        <![CDATA[Introduced last year as a pilot program, the U.S. FDA Commissioner’s National Priority Voucher (CNPV) could be here to stay – at least for the duration of Marty Makary’s tenure as FDA commissioner. Since the FDA unveiled the CNPV last June, it has welcomed 18 products from 16 companies into the “game-changer” program for patients, as Makary described it. The goal is to provide an “ultrafast review pathway,” one to two months instead of the standard 10 to 12 months, for drugs and biologics of strategic national importance while maintaining the FDA’s scientific and regulatory standards, according to the agency.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729950</guid>
      <pubDate>Mon, 30 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729950-us-fda-pondering-next-steps-for-cnpv</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Misc/Paper-airplanes.webp?t=1774904935" type="image/jpeg" medium="image" fileSize="152900">
        <media:title type="plain">Paper airplanes with red leading</media:title>
      </media:content>
    </item>
    <item>
      <title>China-developed triple incretin enters global diabetes race</title>
      <description>
        <![CDATA[A next-generation triple incretin therapy jointly developed by Novo Nordisk A/S and China’s United Biotechnology outperformed semaglutide in a phase II trial, signaling intensifying competition in the GLP-1 obesity and diabetes market.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729901</guid>
      <pubDate>Thu, 26 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729901-china-developed-triple-incretin-enters-global-diabetes-race</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Endocrine-Metabolic-glucose-bloodstream.webp?t=1674056639" type="image/png" medium="image" fileSize="1313266">
        <media:title type="plain">Illustration of glucose molecules in a bloodstream</media:title>
      </media:content>
    </item>
    <item>
      <title>Wave stock shaken, analysts stirred by 007’s obesity phase I </title>
      <description>
        <![CDATA[Apparently put off by data with a higher dose, investors in Wave Life Sciences Inc. backed away after the company rolled out data from the phase I portion of its first-in-human Inlight trial evaluating 250 mg of WVE-007, an INHBE GalNAc-siRNA prospect, in otherwise healthy overweight or obese adults.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729900</guid>
      <pubDate>Thu, 26 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729900-wave-stock-shaken-analysts-stirred-by-007s-obesity-phase-i</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Obesity/obesity-weight.webp?t=1589291306" type="image/png" medium="image" fileSize="227065">
        <media:title type="plain">Tape measure wrapped around feet on scale</media:title>
      </media:content>
    </item>
    <item>
      <title>Study: GLP-1RAs associated with less risk of mental illness getting worse</title>
      <description>
        <![CDATA[In a sea of uncertainty, a large-scale, long-term Swedish study is the first to show that people using GLP-1 receptor agonists are less likely to have worsening mental illness. The study involved a national cohort of 95,490 people diagnosed with depression or anxiety disorder, who also were treated with any diabetes drug (apart from insulin).]]>
      </description>
      <guid>http://www.bioworld.com/articles/729743</guid>
      <pubDate>Thu, 19 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729743-study-glp-1ras-associated-with-less-risk-of-mental-illness-getting-worse</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Mental-illness-art-concept.webp?t=1750710518" type="image/jpeg" medium="image" fileSize="333024">
        <media:title type="plain">Mental illness art concept</media:title>
      </media:content>
    </item>
    <item>
      <title>Triple crown: T2D purse for Lilly’s phase III retatrutide?  </title>
      <description>
        <![CDATA[Further weight loss details are yet to come this year, but Eli Lilly and Co. scored positive top-line results in Transcend-T2D-1, a phase III trial evaluating the efficacy and safety of retatrutide, an investigational first-in-class GIP, GLP-1 and glucagon triple hormone receptor agonist, as an adjunct to diet and exercise in type 2 diabetes (T2D).]]>
      </description>
      <guid>http://www.bioworld.com/articles/729742</guid>
      <pubDate>Thu, 19 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729742-triple-crown-t2d-purse-for-lillys-phase-iii-retatrutide</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Diabetes/Hand-weight-sneakers-scale-measuring-tape-apple-injector-and-glucose-monitor.webp?t=1773954766" type="image/jpeg" medium="image" fileSize="708913">
        <media:title type="plain">Hand weight, sneakers, scale, measuring tape, apple, injector and glucose monitor</media:title>
      </media:content>
    </item>
    <item>
      <title>Promise of exercise in a pill as Atrogi pivots from type 2 diabetes to obesity</title>
      <description>
        <![CDATA[Atrogi AB is making a bid for a slice of the obesity market and has dosed the first overweight subjects with ATR-258, an oral therapy it says mimics the effects of exercise, driving loss of fat whilst sparing muscle.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729562</guid>
      <pubDate>Wed, 18 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729562-promise-of-exercise-in-a-pill-as-atrogi-pivots-from-type-2-diabetes-to-obesity</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/Blue-and-green-pill-with-barbell.webp?t=1773865078" type="image/jpeg" medium="image" fileSize="137491">
        <media:title type="plain">Blue and green pill with barbell</media:title>
      </media:content>
    </item>
    <item>
      <title>Structure’s oral GLP-1 data mark bullish year for obesity pills </title>
      <description>
        <![CDATA[The GLP-1 fight has moved from injectables to pills, and Structure Therapeutics Inc. is in the ring with phase III-ready aleniglipron. According to the Bay Area biotech, its oral once-daily glucagon-like peptide-1 (GLP-1) drug candidate, aleniglipron, demonstrated an absolute weight loss of “up to 39 pounds” in the 44-week Access II trial.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729549</guid>
      <pubDate>Tue, 17 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729549-structures-oral-glp-1-data-mark-bullish-year-for-obesity-pills</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/GLP-1-capsule.webp?t=1766095755" type="image/jpeg" medium="image" fileSize="560029">
        <media:title type="plain">GLP-1 capsule</media:title>
      </media:content>
    </item>
    <item>
      <title>Post-Emanate, Rhythm’s next Imcivree news aHO lot better?</title>
      <description>
        <![CDATA[Low expectations for Rhythm Pharmaceuticals Inc.’s phase III study dubbed Emanate with Imcivree (setmelanotide) in a handful of rare genetic obesities meant hardly any share price consequence, and the stock (NASDAQ:RYTM) closed March 17 at $87.68, down $2.83. “We’re not going to file [for approval] on any of these,” CEO David Meeker said, but the latest findings together represent “a solid building block going forward,” he added.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729545</guid>
      <pubDate>Tue, 17 Mar 2026 12:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729545-post-emanate-rhythms-next-imcivree-news-aho-lot-better</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/Imcivree.webp?t=1773784515" type="image/jpeg" medium="image" fileSize="213993">
        <media:title type="plain">Imcivree</media:title>
        <media:description type="plain">Credit: Rhythm Pharmaceuticals Inc. </media:description>
      </media:content>
    </item>
    <item>
      <title>G2Gbio secures license deal, ₩20B investment from Samsung Epis  </title>
      <description>
        <![CDATA[G2Gbio Inc. secured a ₩20 billion (US$13.35 million) investment from Samsung Epis Holdings Co. Ltd. and a joint research and license agreement for two assets, including a long-acting obesity treatment, with subsidiary Samsung Bioepis Co. Ltd. March 16.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729711</guid>
      <pubDate>Tue, 17 Mar 2026 08:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729711-g2gbio-secures-license-deal-20b-investment-from-samsung-epis</link>
      <media:content url="https://www.bioworld.com/ext/resources/BW-source/2026/G2gbio-Samsung-Bioepis-deal-signing-3-16.webp?t=1774303132" type="image/jpeg" medium="image" fileSize="523115">
        <media:title type="plain">G2gbio-Samsung-Bioepis deal signing</media:title>
        <media:description type="plain">From left: Epis Nexlab CEO Peter (Seong-won) Hong, Samsung Bioepis CEO Kim Kyung-ah and G2Gbio CEO Lee Hee-yong. </media:description>
      </media:content>
    </item>
    <item>
      <title>G2Gbio secures license deal, ₩20B investment from Samsung Epis  </title>
      <description>
        <![CDATA[G2Gbio Inc. secured a ₩20 billion (US$13.35 million) investment from Samsung Epis Holdings Co. Ltd. and a joint research and license agreement for two assets, including a long-acting obesity treatment, with subsidiary Samsung Bioepis Co. Ltd. March 16.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729532</guid>
      <pubDate>Mon, 16 Mar 2026 17:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729532-g2gbio-secures-license-deal-20b-investment-from-samsung-epis</link>
      <media:content url="https://www.bioworld.com/ext/resources/BW-source/2026/G2gbio-Samsung-Bioepis-deal-signing-3-16.webp?t=1774303132" type="image/jpeg" medium="image" fileSize="523115">
        <media:title type="plain">G2gbio-Samsung-Bioepis deal signing</media:title>
        <media:description type="plain">From left: Epis Nexlab CEO Peter (Seong-won) Hong, Samsung Bioepis CEO Kim Kyung-ah and G2Gbio CEO Lee Hee-yong. </media:description>
      </media:content>
    </item>
    <item>
      <title>Zealand touts efficacy, safety for petrelintide phase II obesity trial</title>
      <description>
        <![CDATA[Investors looking for midteen percentage weight loss findings in Zealand Pharma A/S’s phase II study of once-weekly amylin analogue petrelintide were clearly disappointed by the actual 10.7% mean body weight reduction, as shares (Copenhagen:ZEAL) fell 36% March 6. But from the company’s standpoint, the combination of efficacy and safety data from the Zupreme-1 study bode well for a phase III trial expected to start later this year.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729355</guid>
      <pubDate>Fri, 06 Mar 2026 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729355-zealand-touts-efficacy-safety-for-petrelintide-phase-ii-obesity-trial</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Obesity/Man-measuring-waist.webp?t=1696021724" type="image/jpeg" medium="image" fileSize="195747">
        <media:title type="plain">Man measuring waist</media:title>
      </media:content>
    </item>
    <item>
      <title>Study: Weight regain after GLP-1s plateaus below starting weight  </title>
      <description>
        <![CDATA[A new study has reinforced that GLP-1 receptor agonists are unlikely to produce durable weight loss, but indicates that rather than returning to the starting weight, individual weight gain will plateau at 75.5% of the weight lost.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729342</guid>
      <pubDate>Thu, 05 Mar 2026 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729342-study-weight-regain-after-glp-1s-plateaus-below-starting-weight</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Obesity/Bathroom-scale-and-injector-pens.webp?t=1772744223" type="image/jpeg" medium="image" fileSize="929900">
        <media:title type="plain">Bathroom scale and injector pens</media:title>
      </media:content>
    </item>
    <item>
      <title>Jiuyuan seeks approval of Wegovy biosimilar in China</title>
      <description>
        <![CDATA[China’s National Medical Products Administration has accepted for review Jiuyuan Genetic Biopharmaceutical Co. Ltd.’s drug application for Jikeqin, a biosimilar product to Novo Nordisk A/S’s Wegovy (semaglutide) for obesity.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729318</guid>
      <pubDate>Tue, 03 Mar 2026 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729318-jiuyuan-seeks-approval-of-wegovy-biosimilar-in-china</link>
    </item>
    <item>
      <title>Jiuyuan seeks approval of Wegovy biosimilar in China</title>
      <description>
        <![CDATA[China’s National Medical Products Administration has accepted for review Jiuyuan Genetic Biopharmaceutical Co. Ltd.’s drug application for Jikeqin, a biosimilar product to Novo Nordisk A/S’s Wegovy (semaglutide) for obesity.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729245</guid>
      <pubDate>Thu, 26 Feb 2026 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729245-jiuyuan-seeks-approval-of-wegovy-biosimilar-in-china</link>
    </item>
    <item>
      <title>FDA approves Allurion’s gastric balloon system</title>
      <description>
        <![CDATA[The U.S. FDA approved Allurion Technologies Inc.’s premarket application for its swallowable gastric balloon system, which features its Smart Capsule, for weight loss. The clearance is boon for the company as GLP-1 agonists gets increasingly adopted to treat obesity. The approval also brings to the market a new non-invasive option to patients looking for alternative ways to lose weight.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729244</guid>
      <pubDate>Thu, 26 Feb 2026 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729244-fda-approves-allurions-gastric-balloon-system</link>
      <media:content url="https://www.bioworld.com/ext/resources/BW-source/2026/Allurion-Balloon-2-26.webp?t=1772137421" type="image/jpeg" medium="image" fileSize="296746">
        <media:title type="plain">Allurion swallowable gastric balloon</media:title>
        <media:description type="plain">Allurion's swallowable gastric balloon features its Smart Capsule.


Credit: Allurion Technologies Inc.</media:description>
      </media:content>
    </item>
    <item>
      <title>Vivtex’s oral drug delivery approach draws Novo in $2.1B deal</title>
      <description>
        <![CDATA[Coming off a U.S. FDA approval of the first GLP-1 in pill format, Novo Nordisk A/S leaned further into oral drug delivery efforts, partnering with Vivtex Corp. to develop next-generation oral formulations of peptide and protein therapeutics in a potential $2.1 billion deal that marks the highest-profile news for Vivtex since the firm spun out of MIT in 2018.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729200</guid>
      <pubDate>Wed, 25 Feb 2026 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729200-vivtexs-oral-drug-delivery-approach-draws-novo-in-21b-deal</link>
      <media:content url="https://www.bioworld.com/ext/resources/BW-source/2026/GI-ORIS-pic-Vivtex-2-25.webp?t=1772058346" type="image/jpeg" medium="image" fileSize="528373">
        <media:title type="plain">GI-ORIS-pic-Vivtex-2-25.jpg</media:title>
        <media:description type="plain">GI-ORIS, or “GI tract on a chip” screening system.
Credit: Vivtex Corp.</media:description>
      </media:content>
    </item>
    <item>
      <title>Ascletis raises $107M to advance oral GLP-1 to phase III trials </title>
      <description>
        <![CDATA[Ascletis Pharma Inc. raised HK$843.53 million (US107.93 million) in a placement on the Hong Kong Stock Exchange to advance its lead program, ASC-30, a small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist that can be dosed once monthly subcutaneously and once daily orally for treating obesity.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729234</guid>
      <pubDate>Tue, 24 Feb 2026 11:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729234-ascletis-raises-107m-to-advance-oral-glp-1-to-phase-iii-trials</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Money/3D-dollar-sign.webp?t=1624487200" type="image/png" medium="image" fileSize="316216">
        <media:title type="plain">3D dollar sign</media:title>
      </media:content>
    </item>
    <item>
      <title>Viking to push oral GLP-1/GIP drug into phase III obesity trial </title>
      <description>
        <![CDATA[Viking Therapeutics Inc. said after-market hours Feb. 11 that it plans to advance its oral dual GLP-1/GIP receptor, VK-2735, into a phase III trial for obesity in the third quarter of 2026. VK-2735 is a novel dual glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide (GLP-1/GIP) receptor agonist.]]>
      </description>
      <guid>http://www.bioworld.com/articles/728847</guid>
      <pubDate>Thu, 12 Feb 2026 12:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/728847-viking-to-push-oral-glp-1-gip-drug-into-phase-iii-obesity-trial</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/Pills_generic.webp?t=1588352752" type="image/png" medium="image" fileSize="311815">
        <media:title type="plain">Pills and bottle</media:title>
      </media:content>
    </item>
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