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    <title>Immuno-oncology</title>
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    <item>
      <title>CSPC’s SYS-6051 cleared for clinic in China for solid tumors</title>
      <description>
        <![CDATA[CSPC Pharmaceutical Group Ltd.’s SYS-6051 has gained clinical trial clearance from China’s National Medical Products Administration (NMPA) for advanced solid tumors. SYS-6051 is a human tissue factor-targeted antibody-drug conjugate that binds to tissue factor expressed on the surface of tumor cells.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730429</guid>
      <pubDate>Thu, 16 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730429-cspcs-sys-6051-cleared-for-clinic-in-china-for-solid-tumors</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/Antibody-drug-conjugates-ADCs-3D.webp?t=1751620465" type="image/jpeg" medium="image" fileSize="160333">
        <media:title type="plain">3D rendering of an antibody-drug conjugate</media:title>
      </media:content>
    </item>
    <item>
      <title>China’s NMPA accepts Mabwell’s IND application for 6MW5311</title>
      <description>
        <![CDATA[Mabwell (Shanghai) Bioscience Co. Ltd.’s has announced IND acceptance by China’s National Medical Products Administration (NMPA) for the company’s LILRB4/CD3 T-cell engager bispecific antibody 6MW5311. The drug candidate is being developed for hematologic malignancies, specifically acute myeloid leukemia (AML), chronic myelomonocytic leukemia and multiple myeloma.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730428</guid>
      <pubDate>Thu, 16 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730428-chinas-nmpa-accepts-mabwells-ind-application-for-6mw5311</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/AML-cells-acute-myeloid-leukemia.webp?t=1663340307" type="image/png" medium="image" fileSize="1258935">
        <media:title type="plain">Microscopic image of acute myeloid leukemia (AML) cells.</media:title>
        <media:description type="plain">Acute myeloid leukemia cells. Credit: Cincinnati Children's
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      </media:content>
    </item>
    <item>
      <title>Glyconex’s GNX-1021 cleared for clinic in Japan for GI cancers</title>
      <description>
        <![CDATA[Glyconex Inc. has received approval from Japan’s Pharmaceuticals and Medical Devices Agency (PMDA) for the initiation of a first-in-human phase I trial of GNX-1021, the company’s lead antibody-drug conjugate (ADC) candidate, in patients with advanced gastrointestinal (GI) cancers.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730373</guid>
      <pubDate>Wed, 15 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730373-glyconexs-gnx-1021-cleared-for-clinic-in-japan-for-gi-cancers</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Research-and-science/Floating-antibody-drug-conjugates.webp?t=1737562655" type="image/jpeg" medium="image" fileSize="131818">
        <media:title type="plain">Floating antibody drug conjugates</media:title>
      </media:content>
    </item>
    <item>
      <title>KDTV-001: a trivalent HPV vaccine with broad and durable antitumor immunity</title>
      <description>
        <![CDATA[While most human papillomavirus (HPV) infections are cleared by the host immune system, persistent infection with high-risk HPV genotypes, particularly HPV16 and HPV18, can promote cervical cancer development. Researchers from Huazhong University of Science and Technology reported the development and preclinical characterization of KDTV-001, an HPV vaccine comprising a nonreplicating adenovirus type 5 vector encoding a codon-optimized fusion protein of the early antigens E6 and E7 derived from HPV genotypes 16, 18 and 52.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730372</guid>
      <pubDate>Wed, 15 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730372-kdtv-001-a-trivalent-hpv-vaccine-with-broad-and-durable-antitumor-immunity</link>
    </item>
    <item>
      <title>Senescent tumor-derived nanovesicles restore antitumor immunity</title>
      <description>
        <![CDATA[Researchers from Fudan University (Shanghai, China) and collaborators tested the use of senescent tumor cell (STC)-derived nanovesicles to enable spatiotemporally confined immune responses for selective clearance of radiotherapy-induced STCs.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730351</guid>
      <pubDate>Tue, 14 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730351-senescent-tumor-derived-nanovesicles-restore-antitumor-immunity</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Cancer-tumor-illustration.webp?t=1731081970" type="image/jpeg" medium="image" fileSize="313900">
        <media:title type="plain">Illustration of cancer tumor</media:title>
      </media:content>
    </item>
    <item>
      <title>Kazia Therapeutics licenses SETDB1 platform from QIMR Berghofer</title>
      <description>
        <![CDATA[Kazia Therapeutics Ltd. has licensed a first-in-class SETDB1-targeted epigenetic drug development platform from QIMR Berghofer. The company acquired global rights to the SETDB1 platform, including the lead candidate MSETC, in exchange for an up-front payment and a tiered revenue-sharing structure aligned with development progress.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730347</guid>
      <pubDate>Tue, 14 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730347-kazia-therapeutics-licenses-setdb1-platform-from-qimr-berghofer</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Deals-and-MAs/Deals-handshake-analysis-illustration.webp?t=1614643337" type="image/png" medium="image" fileSize="1213840">
        <media:title type="plain">Concept of business partnership</media:title>
      </media:content>
    </item>
    <item>
      <title>Solve Therapeutics patents new anti-5T4 ADCs</title>
      <description>
        <![CDATA[Solve Therapeutics Inc. has disclosed new antibody-drug conjugates (ADCs) comprising antibody or antigen binding fragments targeting trophoblast glycoprotein (TPBG; 5T4) linked to a cytotoxic drug and therefore potentially useful for the treatment of cancer.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730337</guid>
      <pubDate>Mon, 13 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730337-solve-therapeutics-patents-new-anti-5t4-adcs</link>
    </item>
    <item>
      <title>Second CRL for Replimune’s RP-1 for melanoma </title>
      <description>
        <![CDATA[Replimune Group Inc. received another complete response letter (CRL) from the U.S. FDA for immunotherapy vusolimogene oderparepvec to treat advanced melanoma, sending shares plunging by more than 19% on the April 10 PDUFA date.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730363</guid>
      <pubDate>Fri, 10 Apr 2026 17:01:36 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730363-second-crl-for-replimunes-rp-1-for-melanoma</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Dermatologic/Melanoma-skin-cancer-check-dermatologist.webp?t=1743779170" type="image/jpeg" medium="image" fileSize="151014">
        <media:title type="plain">Photo of magnifying glass inspecting moles on person's back</media:title>
      </media:content>
    </item>
    <item>
      <title>Selective CBL-B inhibitor with improved safety profile disclosed</title>
      <description>
        <![CDATA[CBL-B is a RING-type E3 ubiquitin ligase that acts as a negative regulator of T-cell activation, contributing to immune homeostasis by limiting excessive immune responses. In cancer, however, this inhibitory role can impair the immune system’s capacity to detect and eradicate tumor cells. Researchers from Genentech Inc. presented the design and optimization of a series of CBL-B-targeting molecular glues.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730243</guid>
      <pubDate>Thu, 09 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730243-selective-cbl-b-inhibitor-with-improved-safety-profile-disclosed</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Targeted-cancer-cell.webp?t=1748961673" type="image/jpeg" medium="image" fileSize="966728">
        <media:title type="plain">Cancer cell in the cross-hairs</media:title>
      </media:content>
    </item>
    <item>
      <title>Next-generation anti-CD30 ADC outperforms brentuximab vedotin</title>
      <description>
        <![CDATA[Researchers from Mabqi SAS presented the preclinical profile of MQI-181, an antibody-drug conjugate (ADC) composed of a human anti-CD30 antibody (18D03) linked to the cytotoxic payload monomethyl auristatin E (MMAE) via a cleavable MC-VC-PAB linker, with a drug-antibody ratio of 4.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730169</guid>
      <pubDate>Tue, 07 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730169-next-generation-anti-cd30-adc-outperforms-brentuximab-vedotin</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Cancer-antibody-therapy.webp?t=1744729079" type="image/jpeg" medium="image" fileSize="215111">
        <media:title type="plain">Illustration of antibodies targeting cancer cell </media:title>
      </media:content>
    </item>
    <item>
      <title>Canwell gains IND clearance for ADC CAN-016</title>
      <description>
        <![CDATA[Canwell Pharma Inc. has obtained IND approval from the FDA for CAN-016, a novel antibody-drug conjugate (ADC). The company will initiate a phase I study in patients with HER2-expressing solid tumors who have experienced disease progression following prior ADC therapies.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730166</guid>
      <pubDate>Tue, 07 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730166-canwell-gains-ind-clearance-for-adc-can-016</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Antibodies-research-discovery-immune.webp?t=1772641847" type="image/jpeg" medium="image" fileSize="240482">
        <media:title type="plain">Illustration of magnifying glass and antibodies</media:title>
      </media:content>
    </item>
    <item>
      <title>Akari Therapeutics partners with Wuxi XDC on ADC payload</title>
      <description>
        <![CDATA[Akari Therapeutics plc has established a strategic partnership with Wuxi XDC Cayman Inc. to accelerate the development of Akari’s novel PH1 payload. Akari’s lead program, AKTX-101, is initially targeting metastatic urothelial cancer.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730165</guid>
      <pubDate>Tue, 07 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730165-akari-therapeutics-partners-with-wuxi-xdc-on-adc-payload</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Antibody-drug-conjugate-cytotoxic-payload.webp?t=1690210650" type="image/jpeg" medium="image" fileSize="142424">
        <media:title type="plain">3D rendering of antibody drug conjugated with cytotoxic payload</media:title>
      </media:content>
    </item>
    <item>
      <title>Janux nominates development candidate under BMS collaboration</title>
      <description>
        <![CDATA[Janux Therapeutics Inc. has nominated a development candidate under its collaboration and exclusive worldwide license agreement with Bristol Myers Squibb Co. (BMS). The milestone was achieved following the identification of a tumor-activated therapeutic, utilizing Janux’s TRACTr (Tumor Activated T Cell Engager) platform, targeting an undisclosed solid tumor antigen expressed across several human cancer types. The milestone triggers a payment to Janux.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730099</guid>
      <pubDate>Thu, 02 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730099-janux-nominates-development-candidate-under-bms-collaboration</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/cancer-tumor.webp?t=1709569099" type="image/jpeg" medium="image" fileSize="358193">
        <media:title type="plain">Illustration of tumor</media:title>
      </media:content>
    </item>
    <item>
      <title>Ernexa eyes clinic with ERNA-101 for ovarian cancer</title>
      <description>
        <![CDATA[Ernexa Therapeutics Inc. is advancing its lead program, ERNA-101, toward an IND submission in the third quarter of this year and the initiation of a first-in-human trial in the fourth quarter for the treatment of platinum-resistant ovarian cancer.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730095</guid>
      <pubDate>Thu, 02 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730095-ernexa-eyes-clinic-with-erna-101-for-ovarian-cancer</link>
    </item>
    <item>
      <title>Fosun gains clinical trial approval in China for FXB-0871</title>
      <description>
        <![CDATA[Fosun Pharmaceutical (Group) Co. Ltd. has received the approval from China’s National Medical Products Administration (NMPA) to initiate a clinical trial of FXB-0871 (TEV-56278) for the treatment of locally advanced or metastatic solid tumors.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730093</guid>
      <pubDate>Thu, 02 Apr 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730093-fosun-gains-clinical-trial-approval-in-china-for-fxb-0871</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Cancer-tumor-blood-vessels.webp?t=1691420296" type="image/jpeg" medium="image" fileSize="242637">
        <media:title type="plain">3D illustration of tumor</media:title>
      </media:content>
    </item>
    <item>
      <title>Tyligand Bioscience divulges new dual-drug antibody-drug conjugates</title>
      <description>
        <![CDATA[Tyligand Bioscience Ltd. has reported new dual-drug antibody-drug conjugates comprising monoclonal antibodies covalently linked to stimulator of interferon genes protein (STING; TMEM173) agonist and a cytotoxic drug.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730048</guid>
      <pubDate>Tue, 31 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730048-tyligand-bioscience-divulges-new-dual-drug-antibody-drug-conjugates</link>
    </item>
    <item>
      <title>Antitumoral antibodies cross the BBB and alter brain signaling</title>
      <description>
        <![CDATA[Certain cancers, such as triple-negative breast cancer, produce antibodies that, although they help fight the tumor, can cross the blood-brain barrier and alter the function of NMDA receptors (NMDAR) in the brain, which are essential for neuronal signaling. Scientists at Cold Spring Harbor Laboratory (CSHL) have identified their origin and described how this process is linked to the maturation of these antibodies, which can activate or inhibit the receptor, causing neurological and psychiatric symptoms.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730035</guid>
      <pubDate>Tue, 31 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730035-antitumoral-antibodies-cross-the-bbb-and-alter-brain-signaling</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Neurology-immune-neuron-antibodies.webp?t=1774968985" type="image/jpeg" medium="image" fileSize="356156">
        <media:title type="plain">Antibodies and synaptic neuron</media:title>
      </media:content>
    </item>
    <item>
      <title>CGT-19 as an approach to expand CAR T-cell therapy accessibility</title>
      <description>
        <![CDATA[The use of CAR T-cell therapy has transformed outcomes for relapsed or refractory B-cell malignancies, but access to it remains extremely limited in some countries. Cartogene Therapeutics Pvt Ltd. aimed to address this need by in-licensing CGT-19, a CD19 CAR T construct from Vector Biomed Inc.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730015</guid>
      <pubDate>Mon, 30 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730015-cgt-19-as-an-approach-to-expand-car-t-cell-therapy-accessibility</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/CAR-CD19-binding.webp?t=1665503757" type="image/png" medium="image" fileSize="2301092">
        <media:title type="plain">CD19 binding </media:title>
      </media:content>
    </item>
    <item>
      <title>CAR T targeting CD44E splicing variant shows potential for HCC treatment</title>
      <description>
        <![CDATA[Previously, Chinese researchers used long-read RNA sequencing to identify a unique alternative splicing variant of CD44 transmembrane protein, named CD44E, which is highly expressed in hepatocellular carcinoma (HCC) tumors compared to adjacent nontumoral liver tissues. In a new study, the team analyzed the Genotype-Tissue Expression (GTEx) database and confirmed that CD44E expression is limited in essential normal organs, while CD44S standard isoform is broadly expressed on most cell types.]]>
      </description>
      <guid>http://www.bioworld.com/articles/730000</guid>
      <pubDate>Fri, 27 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/730000-car-t-targeting-cd44e-splicing-variant-shows-potential-for-hcc-treatment</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/HCC-hepatocellular-carcinoma-liver-cancer.webp?t=1722888982" type="image/jpeg" medium="image" fileSize="265067">
        <media:title type="plain">Illustration of tumor in the liver</media:title>
      </media:content>
    </item>
    <item>
      <title>More than two to tango: multispecifics at ESMO TAT</title>
      <description>
        <![CDATA[Multispecifics took center stage at this year’s ESMO TAT, emerging as one of the hottest trends in oncology research. Unlike traditional small-molecule drugs or monoclonal antibodies that typically target a single protein, multispecific compounds are engineered to harness multiple mechanisms of action within a single molecule. They orchestrate biology rather than just blocking it.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729995</guid>
      <pubDate>Fri, 27 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729995-more-than-two-to-tango-multispecifics-at-esmo-tat</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Immune-antibodies-green-blue.webp?t=1774622975" type="image/jpeg" medium="image" fileSize="569236">
        <media:title type="plain">Antibodies artwork</media:title>
      </media:content>
    </item>
    <item>
      <title>The Scripps Research Institute identifies new DNA topoisomerase inhibitors</title>
      <description>
        <![CDATA[The Scripps Research Institute has discovered new bicyclo[1.1.1]pentane-based DNA topoisomerase inhibitors and antibody-drug conjugates comprising a monoclonal antibody covalently linked to a DNA topoisomerase inhibitor. They are described as potentially useful for the treatment of cancer.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729942</guid>
      <pubDate>Thu, 26 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729942-the-scripps-research-institute-identifies-new-dna-topoisomerase-inhibitors</link>
    </item>
    <item>
      <title>Bolt Biotherapeutics discloses new STING agonist immunoconjugates</title>
      <description>
        <![CDATA[Bolt Biotherapeutics Inc. has prepared and tested new immunoconjugates comprising antibodies covalently linked to stimulator of interferon genes protein (STING; TMEM173) agonists. They are designed for potential use in the treatment of cancer.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729941</guid>
      <pubDate>Thu, 26 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729941-bolt-biotherapeutics-discloses-new-sting-agonist-immunoconjugates</link>
    </item>
    <item>
      <title>Oncolytic virotherapy boosts antitumor immunity in cSCC</title>
      <description>
        <![CDATA[Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, arising from abnormal proliferation of epidermal keratinocytes due to chronic UV exposure. While highly curable (>90%) with surgical excision when detected early, it carries a significant risk of local invasion and metastasis if left untreated.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729876</guid>
      <pubDate>Wed, 25 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729876-oncolytic-virotherapy-boosts-antitumor-immunity-in-cscc</link>
    </item>
    <item>
      <title>Overt Bio advances OVT-101 toward clinic</title>
      <description>
        <![CDATA[Overt Bio Inc. is advancing lead asset OVT-101 toward the clinic. The allogeneic, potential first-in-class, off-the-shelf γδ CAR T therapy targets claudin-6, which is present in the majority of ovarian cancers and several other solid tumors.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729861</guid>
      <pubDate>Tue, 24 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729861-overt-bio-advances-ovt-101-toward-clinic</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Sexual-health/Ovarian-cancer.webp?t=1589293151" type="image/png" medium="image" fileSize="197603">
        <media:title type="plain">Ovarian cancer illustration</media:title>
      </media:content>
    </item>
    <item>
      <title>Glyconex and Nippon Kayaku collaborate on GNX201-ADC</title>
      <description>
        <![CDATA[Glyconex Inc. has entered into a collaboration agreement with Nippon Kayaku Co. Ltd. to advance GNX201-ADC, a next-generation glycan-directed antibody-drug conjugate (ADC) candidate for the treatment of solid tumors.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729857</guid>
      <pubDate>Tue, 24 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729857-glyconex-and-nippon-kayaku-collaborate-on-gnx201-adc</link>
    </item>
    <item>
      <title>Kelun-Biotech’s SKB-103 cleared to enter clinic in China</title>
      <description>
        <![CDATA[Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. has announced IND approval by China’s National Medical Products Administration (NMPA) for SKB-103 for the treatment of advanced solid tumors.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729855</guid>
      <pubDate>Tue, 24 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729855-kelun-biotechs-skb-103-cleared-to-enter-clinic-in-china</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Antibody-Drug-Conjugate-Molecules-ADC.webp?t=1671207526" type="image/png" medium="image" fileSize="887488">
        <media:title type="plain">3D illustration demonstrating antibody-drug conjugate.</media:title>
      </media:content>
    </item>
    <item>
      <title>DLL3-targeted T-cell therapy shows efficacy in MTC models</title>
      <description>
        <![CDATA[Medullary thyroid carcinoma (MTC) is a rare, often aggressive, neuroendocrine thyroid tumor with limited targeted treatment options, arising from calcitonin-producing C cells and sometimes associated with RET mutations. Researchers from the Mayo Clinic reported the potential of targeting DLL3 as a therapeutic strategy in MTC.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729793</guid>
      <pubDate>Mon, 23 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729793-dll3-targeted-t-cell-therapy-shows-efficacy-in-mtc-models</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Cancer-cells-and-immunotherapy.webp?t=1623784162" type="image/png" medium="image" fileSize="495987">
        <media:title type="plain">Illustration of cancer cells and immunotherapy treatment</media:title>
      </media:content>
    </item>
    <item>
      <title>First-in-class anti-TRPV6 antibody for advanced prostate cancer</title>
      <description>
        <![CDATA[At the ESMO Targeted Anticancer Therapies Congress held this week in Paris, researchers at Mabqi SAS presented the preclinical characterization of MQI-201, an anti-TRPV6 therapeutic antibody in models of metastatic prostate cancer.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729773</guid>
      <pubDate>Fri, 20 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729773-first-in-class-anti-trpv6-antibody-for-advanced-prostate-cancer</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Cancer-prostate-illustration.webp?t=1721838477" type="image/jpeg" medium="image" fileSize="115372">
        <media:title type="plain">3D illustration showing presence of tumor inside prostate gland </media:title>
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      <title>ENPP1 inhibitors show promise for cancer immunotherapy</title>
      <description>
        <![CDATA[Researchers from Sungkyunkwan University and Txinno Bioscience Inc. recently presented their work where they aimed to design, synthesize and evaluate ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitors containing a benzotriazole core and a sulfonimidamide Zn binder.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729723</guid>
      <pubDate>Thu, 19 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729723-enpp1-inhibitors-show-promise-for-cancer-immunotherapy</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/Cancer-cell-colorful-vials-research-science.webp?t=1764171255" type="image/jpeg" medium="image" fileSize="1070259">
        <media:title type="plain">Concept art for oncology research</media:title>
      </media:content>
    </item>
    <item>
      <title>Nanobody CAR construct targeting CLL-1 shows preclinical activity against AML</title>
      <description>
        <![CDATA[Researchers from the Sino-American Cancer Foundation and Taipei Medical University have developed a novel nanobody-based CAR T-cell platform directed against C-type lectin-like molecule-1 (CLL-1) for the possible treatment of acute myeloid leukemia (AML).]]>
      </description>
      <guid>http://www.bioworld.com/articles/729694</guid>
      <pubDate>Wed, 18 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729694-nanobody-car-construct-targeting-cll-1-shows-preclinical-activity-against-aml</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Research-and-science/Nanoparticle-illustration.webp?t=1735833924" type="image/jpeg" medium="image" fileSize="311893">
        <media:title type="plain">Nanoparticle illustration </media:title>
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