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    <title>HIV/AIDS</title>
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    <item>
      <title>Approach to enhance CAR T efficacy in infectious diseases and cancer</title>
      <description>
        <![CDATA[CAR T-cell therapy can be applied to treat some chronic infectious diseases, particularly to provide a functional cure for HIV-1 in people living with HIV. However, the effectiveness of CAR T cells for persistent suppression of HIV still faces many constraints, including the high mutation rate of reverse transcriptase, which enables the emergence of immune escape viral variants.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729932</guid>
      <pubDate>Thu, 26 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729932-approach-to-enhance-car-t-efficacy-in-infectious-diseases-and-cancer</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/NIH-NIAID-HIV.webp?t=1724423365" type="image/jpeg" medium="image" fileSize="446919">
        <media:title type="plain">Transmission electron micrograph of HIV particles</media:title>
        <media:description type="plain">HIV-1 virus particles (colorized yellow) replicating from an HIV-infected H9 T cell (pink). Credit: NIAID, NIH</media:description>
      </media:content>
    </item>
    <item>
      <title>Grant supports Tessera’s genetic approaches to HIV cure</title>
      <description>
        <![CDATA[Tessera Therapeutics Inc. has received a grant from the Gates Foundation to support early-stage research exploring multiple genetic approaches aimed at developing a scalable cure for HIV. This research will evaluate several potential strategies leveraging Tessera’s Gene Writing platform to engineer immune cells in vivo.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729794</guid>
      <pubDate>Mon, 23 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729794-grant-supports-tesseras-genetic-approaches-to-hiv-cure</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Research-and-science/Gene-therapy-illustration.webp?t=1608150701" type="image/png" medium="image" fileSize="436394">
        <media:title type="plain">DNA in drug capsules</media:title>
      </media:content>
    </item>
    <item>
      <title>Shionogi patents new agents for HIV-1 infection</title>
      <description>
        <![CDATA[Shionogi & Co. Ltd. has disclosed heterocyclic derivatives characterized as reverse transcriptase/ribonuclease H (HIV-1) inhibitors for potential use in the treatment of HIV infection.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729519</guid>
      <pubDate>Tue, 10 Mar 2026 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/729519-shionogi-patents-new-agents-for-hiv-1-infection</link>
    </item>
    <item>
      <title>KLF16 as potential target for HIV management</title>
      <description>
        <![CDATA[HIV-1 persistence in latent reservoirs of T lymphoid and myeloid origin is a major barrier for the cure of the disease, with complex and multifactorial mechanisms behind HIV-1 latency; thus, investigating these mechanisms is key for future targeted HIV therapies.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729376</guid>
      <pubDate>Thu, 05 Mar 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729376-klf16-as-potential-target-for-hiv-management</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/NHI-NIAID-HIV-1-virus-particles-pink.webp?t=1752677386" type="image/jpeg" medium="image" fileSize="1133167">
        <media:title type="plain">Transmission electron micrograph of HIV-1 virus particles</media:title>
        <media:description type="plain">HIV-1 virus particles. Credit: NIAID, CC BY 2.0</media:description>
      </media:content>
    </item>
    <item>
      <title>Preclinical data support continued testing of Gilead’s HIV candidate GS-3242</title>
      <description>
        <![CDATA[Gilead Sciences Inc.’s integrase strand transfer inhibitor (INSTI) GS-3242 is in early clinical development for HIV infection (NCT07001319). The company presented nonclinical data on the candidate at the recent CROI meeting in Denver.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729373</guid>
      <pubDate>Thu, 05 Mar 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729373-preclinical-data-support-continued-testing-of-gileads-hiv-candidate-gs-3242</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Infectious/HIV-infected-cell-Credit-NIAID.webp?t=1772724323" type="image/png" medium="image" fileSize="757353">
        <media:title type="plain">HIV-infected cell</media:title>
        <media:description type="plain">HIV-infected cell. Credit: NIAID</media:description>
      </media:content>
    </item>
    <item>
      <title>Anticancer drug exerts potent HIV antiviral effects</title>
      <description>
        <![CDATA[A new isoform of proliferating cell nuclear antigen (PCNA) – cancer-associated PCNA (caPCNA) – that is specifically expressed in cancer tissues has been reported. Because cancer cells and HIV-infected cells have similar features, researchers from City of Hope National Medical Center tested the anit-HIV effects of a small-molecule compound, AOH-1996, that targets caPCNA.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729327</guid>
      <pubDate>Wed, 04 Mar 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729327-anticancer-drug-exerts-potent-hiv-antiviral-effects</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/HIV-AIDS-viral-structure.webp?t=1707321297" type="image/jpeg" medium="image" fileSize="238698">
        <media:title type="plain">Cross section illustration of HIV virus parts</media:title>
      </media:content>
    </item>
    <item>
      <title>BNT-351, long-acting bNAb with potent HIV neutralization</title>
      <description>
        <![CDATA[Broadly neutralizing antibodies (bNAbs) target conserved HIV envelope regions to neutralize diverse strains, eliminate infected cells and reduce viral reservoirs, complementing antiretroviral therapy and supporting prevention and functional cure strategies.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729134</guid>
      <pubDate>Mon, 02 Mar 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729134-bnt-351-long-acting-bnab-with-potent-hiv-neutralization</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Infectious/3D-HIV.webp?t=1709829200" type="image/jpeg" medium="image" fileSize="273128">
        <media:title type="plain">Illustration of HIV particles</media:title>
      </media:content>
    </item>
    <item>
      <title>CROI 2026: Science and funding cuts reverse decades of progress against HIV</title>
      <description>
        <![CDATA[The massive cuts to science, global health, and HIV programs that unfolded in 2025 triggered a crisis with worldwide repercussions. The dissolution of USAID, the shutdown of PEPFAR, and the suspension of thousands of NIH research projects led to an immediate collapse of essential services, from HIV prevention to access to treatment. At the 33rd Conference on Retroviruses and Opportunistic Infections (CROI) held Feb. 22-25, 2026, in Denver, scientists, activists, and health professionals presented data illustrating the scale of the damage and warned of a historic setback in the global HIV response.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729112</guid>
      <pubDate>Fri, 27 Feb 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729112-croi-2026-science-and-funding-cuts-reverse-decades-of-progress-against-hiv</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/HIV-with-graphs-numbers-and-map.webp?t=1772205424" type="image/jpeg" medium="image" fileSize="1068230">
        <media:title type="plain">HIV with graphs, numbers and map</media:title>
      </media:content>
    </item>
    <item>
      <title>CROI 2026 highlights depression and cognitive vulnerability in HIV</title>
      <description>
        <![CDATA[The effects of aging pose an additional challenge for people with HIV due to the neurological and psychological consequences that persist despite antiretroviral therapy. At the Conference on Retroviruses and Opportunistic Infections (CROI) held Feb. 22-25, 2026, in Denver, the scientific community examined how the virus affects the brain, how the reservoir is established in the CNS, and which genetic, immunological or treatment-related factors influence cognitive health.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729051</guid>
      <pubDate>Thu, 26 Feb 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729051-croi-2026-highlights-depression-and-cognitive-vulnerability-in-hiv</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Depression-concept-with-human-broken-brain-and-heavy-rain.webp?t=1772119734" type="image/jpeg" medium="image" fileSize="692951">
        <media:title type="plain">Depression concept with human, broken brain and heavy rain</media:title>
      </media:content>
    </item>
    <item>
      <title>MDL-001: oral polymerase inhibitor with dual HBV/HCV activity </title>
      <description>
        <![CDATA[Researchers from Model Medicines Inc. have presented preclinical efficacy data for MDL-001, a first-in-class, oral non-nucleoside inhibitor that targets an allosteric site in the Thumb-1 domain of the viral polymerase.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729032</guid>
      <pubDate>Wed, 25 Feb 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729032-mdl-001-oral-polymerase-inhibitor-with-dual-hbv-hcv-activity</link>
    </item>
    <item>
      <title>CROI 2026: Neurodegeneration, the challenge of aging with HIV  </title>
      <description>
        <![CDATA[Antiretroviral therapies against HIV have been in use for more than 30 years and have enabled people living with HIV to maintain undetectable viral levels. Many of them are aging in good health. However, others present symptoms of cognitive decline. HIV can reach the brain and establish a reservoir there. Yet, it is still unknown what this reservoir is like, which cells are affected, and which comorbidities are typical of aging or are associated with the virus.]]>
      </description>
      <guid>http://www.bioworld.com/articles/729031</guid>
      <pubDate>Wed, 25 Feb 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/729031-croi-2026-neurodegeneration-the-challenge-of-aging-with-hiv</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/Brain-and-virus-with-chromosome.webp?t=1772031510" type="image/jpeg" medium="image" fileSize="1307640">
        <media:title type="plain">Brain and virus with chromosome</media:title>
      </media:content>
    </item>
    <item>
      <title>DNA origami vaccine produces broadly neutralizing HIV antibodies</title>
      <description>
        <![CDATA[The use of DNA scaffolds could mark a turning point in HIV vaccine design. Scientists at Scripps Research and the Massachusetts Institute of Technology (MIT) have created a new vaccine platform based on DNA origami, a material that the immune system does not recognize as a threat, avoiding unwanted responses.]]>
      </description>
      <guid>http://www.bioworld.com/articles/728827</guid>
      <pubDate>Fri, 13 Feb 2026 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/728827-dna-origami-vaccine-produces-broadly-neutralizing-hiv-antibodies</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-source/DNA-based-vaccine-MIT-Scripps-hero.webp?t=1770996481" type="image/jpeg" medium="image" fileSize="646327">
        <media:title type="plain">Illustration of DNA-based vaccine for HIV</media:title>
        <media:description type="plain">The DNA-based vaccine induces antibodies to the HIV antigen (blue) without eliciting antibodies to the DNA particle (gray), whereas the protein-based vaccine generates antibodies to both the HIV antigen (blue) and the protein particle (red). Image created by Grant Knappe (MIT) based on atomic models from MIT (DNA-based vaccine) and Scripps Research (protein-based vaccine). Credits: MIT and Scripps Research</media:description>
      </media:content>
    </item>
    <item>
      <title>Vaccines: From the toast of the town to being in the crosshairs</title>
      <description>
        <![CDATA[BioWorld’s 2022 end-of-year highlights included a toast to the future – of universal vaccines. Even before SARS-CoV-2 vaccines were developed in record time and saved countless lives during the COVID-19 pandemic, vaccines were a rare bright spot in the fight against infectious diseases. Bacteria are becoming multidrug resistant far faster than new classes of antibiotics are being developed, viral spillover events and vector ranges are increasing, and climate change is helping bacteria and fungi alike breach human thermal protections against infections.]]>
      </description>
      <guid>http://www.bioworld.com/articles/727420</guid>
      <pubDate>Tue, 23 Dec 2025 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/727420-vaccines-from-the-toast-of-the-town-to-being-in-the-crosshairs</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Infectious/COVID-19-vaccine-domino.webp?t=1766503415" type="image/jpeg" medium="image" fileSize="195425">
        <media:title type="plain">COVID-19 vial in a line of toppled dominoes</media:title>
      </media:content>
    </item>
    <item>
      <title>HIV research is close to a cure but far from ending the pandemic</title>
      <description>
        <![CDATA[Advances in antiretroviral therapy (ART) now allow people living with HIV to lead normal lives with undetectable and nontransmissible levels of the virus in their blood. Yet that reality is limited to those with access to treatment. More than 40 million people worldwide live with HIV, with over a million new infections and hundreds of thousands of deaths each year, underscoring that major challenges remain.]]>
      </description>
      <guid>http://www.bioworld.com/articles/727259</guid>
      <pubDate>Thu, 18 Dec 2025 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/727259-hiv-research-is-close-to-a-cure-but-far-from-ending-the-pandemic</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-source/NIAID-Fauci-HIV.webp?t=1766074846" type="image/jpeg" medium="image" fileSize="792810">
        <media:title type="plain">Left: Anthony Fauci. Right: Transmission electron micrograph of HIV-1 virus particles </media:title>
        <media:description type="plain">Left: Anthony Fauci. Right: Transmission electron micrograph of HIV-1 virus particles (blue) replicating from the plasma membrane of an H9 T cell (green). Image captured at the NIAID Integrated Research Facility in Fort Detrick, Maryland. Credit: NIAID. Licensed under CC-BY 2.0.</media:description>
      </media:content>
    </item>
    <item>
      <title>Peptidomimetic against drug-resistant HIV-1</title>
      <description>
        <![CDATA[Many cases of human immunodeficiency virus (HIV)-1 infection can be effectively treated with existing drugs, but they can lose efficacy over time because of the emergence of resistance. In an effort to generate next-generation drugs, Chinese researchers at the Chinese Academy of Medical Sciences & Peking Union Medical College and other institutions synthesized a series of peptidomimetics against the viral protease, in which they extended the therapeutically effective hydroxyethyl sulfonamide scaffold using an amino acid linker. They reasoned that the linker could allow the drug to make additional contacts with the protease.]]>
      </description>
      <guid>http://www.bioworld.com/articles/727043</guid>
      <pubDate>Thu, 11 Dec 2025 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/727043-peptidomimetic-against-drug-resistant-hiv-1</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-source/CROI-resized.webp?t=1676909780" type="image/png" medium="image" fileSize="1846657">
        <media:title type="plain">HIV-1 virus particle</media:title>
        <media:description type="plain">HIV-1 virus particle. Credit: National Institute of Allergy and Infectious Diseases.</media:description>
      </media:content>
    </item>
    <item>
      <title>HIV remission after heterozygous CCR5Δ32 stem cell transplant</title>
      <description>
        <![CDATA[2025 has been the most challenging year in the efforts to fight HIV since at least the advent of antiretroviral therapy. In a report on “Overcoming disruption, transforming the AIDS response,” released last week ahead of World AIDS Day on Dec. 1, the Joint United Nations Program on HIV/AIDS (UNAIDS) described “a global system in shock” by sharply reduced funding from the U.S. and other wealthy nations. Scientifically, for now, progress is ongoing.]]>
      </description>
      <guid>http://www.bioworld.com/articles/726796</guid>
      <pubDate>Tue, 02 Dec 2025 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/726796-hiv-remission-after-heterozygous-ccr532-stem-cell-transplant</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/HIV-AIDS-Red-Blood-Cells.webp?t=1764605960" type="image/jpeg" medium="image" fileSize="1467646">
        <media:title type="plain">Illustration of HIV/AIDS virus in the bloodstream</media:title>
      </media:content>
    </item>
    <item>
      <title>HIV remission after heterozygous CCR5Δ32 stem cell transplant</title>
      <description>
        <![CDATA[2025 has been the most challenging year in the efforts to fight HIV since at least the advent of antiretroviral therapy. In a report on “Overcoming disruption, transforming the AIDS response,” released last week ahead of World AIDS Day on Dec. 1, the Joint United Nations Program on HIV/AIDS (UNAIDS) described “a global system in shock” by sharply reduced funding from the U.S. and other wealthy nations. Scientifically, for now, progress is ongoing. To mark World AIDS Day, <em>Nature</em> published three independent studies on HIV.]]>
      </description>
      <guid>http://www.bioworld.com/articles/726666</guid>
      <pubDate>Mon, 01 Dec 2025 08:00:00 -0500</pubDate>
      <link>https://www.bioworld.com/articles/726666-hiv-remission-after-heterozygous-ccr532-stem-cell-transplant</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/HIV-AIDS-Red-Blood-Cells.webp?t=1764605960" type="image/jpeg" medium="image" fileSize="1467646">
        <media:title type="plain">Illustration of HIV/AIDS virus in the bloodstream</media:title>
      </media:content>
    </item>
    <item>
      <title>Combining multiple HIV epitopes elicits broad antibody responses</title>
      <description>
        <![CDATA[In vaccine development, one might think that targeting multiple epitopes increases the likelihood of improving outcomes. However, when several immunogens are administered together, the immune system does not always generate antibodies against all of them. Two parallel studies have overcome this challenge by using multiple simultaneous immunogens against HIV, effectively triggering various types of broadly neutralizing antibody (bnAb) precursors in two different preclinical animal models.]]>
      </description>
      <guid>http://www.bioworld.com/articles/725342</guid>
      <pubDate>Mon, 20 Oct 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/725342-combining-multiple-hiv-epitopes-elicits-broad-antibody-responses</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/HIV-cross-section-3D-virus.webp?t=1760972304" type="image/jpeg" medium="image" fileSize="858510">
        <media:title type="plain">Cross section of an HIV virus particle</media:title>
      </media:content>
    </item>
    <item>
      <title>HIV-1 targeted activator of cell kill compounds divulged in MSD patent</title>
      <description>
        <![CDATA[Merck Sharp & Dohme LLC (MSD) has synthesized new <em>N</em>-oxide derivative targeted activator of cell kill (TACK) compounds acting as Gag polyprotein (HIV-1)/protein Pol dimerization inducers reported to be useful for the treatment of HIV infection.]]>
      </description>
      <guid>http://www.bioworld.com/articles/724971</guid>
      <pubDate>Wed, 08 Oct 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/724971-hiv-1-targeted-activator-of-cell-kill-compounds-divulged-in-msd-patent</link>
    </item>
    <item>
      <title>Deep dive nets sex differences in HIV reservoir</title>
      <description>
        <![CDATA[Globally, over half of people living with HIV are women. But in clinical cure trials, they make up only about 20% of participants. And that gender imbalance is causing researchers to miss out on ways to improve cure strategies. Because women’s immune systems appear to be better at controlling HIV infection in a way that silences the reservoir – the provirus integrated into host cells in infected persons.]]>
      </description>
      <guid>http://www.bioworld.com/articles/724589</guid>
      <pubDate>Wed, 24 Sep 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/724589-deep-dive-nets-sex-differences-in-hiv-reservoir</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/NIH-NIAID-HIV.webp?t=1724423365" type="image/jpeg" medium="image" fileSize="446919">
        <media:title type="plain">Transmission electron micrograph of HIV particles</media:title>
        <media:description type="plain">HIV-1 virus particles (colorized yellow) replicating from an HIV-infected H9 T cell (pink). Credit: NIAID, NIH</media:description>
      </media:content>
    </item>
    <item>
      <title>Deep dive nets sex differences in HIV reservoir</title>
      <description>
        <![CDATA[Globally, over half of people living with HIV are women. But in clinical cure trials, they make up only about 20% of participants. And that gender imbalance is causing researchers to miss out on ways to improve cure strategies. Because women’s immune systems appear to be better at controlling HIV infection in a way that silences the reservoir – the provirus integrated into host cells in infected persons.]]>
      </description>
      <guid>http://www.bioworld.com/articles/724431</guid>
      <pubDate>Tue, 23 Sep 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/724431-deep-dive-nets-sex-differences-in-hiv-reservoir</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/NIH-NIAID-HIV.webp?t=1724423365" type="image/jpeg" medium="image" fileSize="446919">
        <media:title type="plain">Transmission electron micrograph of HIV particles</media:title>
        <media:description type="plain">HIV-1 virus particles (colorized yellow) replicating from an HIV-infected H9 T cell (pink). Credit: NIAID, NIH</media:description>
      </media:content>
    </item>
    <item>
      <title>Gilead discovers new compounds for HIV infection</title>
      <description>
        <![CDATA[A Gilead Sciences Inc. patent describes new compounds acting as pyroptosis inducers reported to be useful for the treatment of HIV infections.]]>
      </description>
      <guid>http://www.bioworld.com/articles/724425</guid>
      <pubDate>Mon, 22 Sep 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/724425-gilead-discovers-new-compounds-for-hiv-infection</link>
    </item>
    <item>
      <title>NIAID grant supports pediatric vaccine for HIV</title>
      <description>
        <![CDATA[The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a 5-year $20.8 million grant to a multi-institutional team led by Weill Cornell Medicine investigators for advanced preclinical development of a promising experimental HIV vaccine. ]]>
      </description>
      <guid>http://www.bioworld.com/articles/724352</guid>
      <pubDate>Fri, 19 Sep 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/724352-niaid-grant-supports-pediatric-vaccine-for-hiv</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/HIV-vaccine-vial-syringe.webp?t=1758291416" type="image/jpeg" medium="image" fileSize="423875">
        <media:title type="plain">Photo of syringe with vial that reads HIV vaccine</media:title>
      </media:content>
    </item>
    <item>
      <title>Merck’s MK-8527 enables long-acting HIV-1 prevention</title>
      <description>
        <![CDATA[Nucleoside reverse transcriptase translocation inhibitors (NRTTIs) are a novel class of antiretroviral agents that inhibit HIV replication by targeting the viral reverse transcriptase enzyme and specifically blocking its translocation step during DNA synthesis, a critical process in the viral replication cycle.]]>
      </description>
      <guid>http://www.bioworld.com/articles/724136</guid>
      <pubDate>Mon, 15 Sep 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/724136-mercks-mk-8527-enables-long-acting-hiv-1-prevention</link>
    </item>
    <item>
      <title>The domino effect of cutting mRNA vaccine research</title>
      <description>
        <![CDATA[In August, a press release from HHS announced the cancellation of 22 vaccine research projects based on mRNA, the latest available technology aimed at developing therapies for viral infections, cancer, and genetic conditions. What happens to mRNA innovation when funding dries up? This series explores how reductions in funding could impact mRNA technology, affecting innovation, research and future therapies.]]>
      </description>
      <guid>http://www.bioworld.com/articles/724135</guid>
      <pubDate>Mon, 15 Sep 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/724135-the-domino-effect-of-cutting-mrna-vaccine-research</link>
      <media:content url="https://www.bioworld.com/ext/resources/Stock-images/Drugs/Vial-and-syringe-in-row-of-dominoes.webp?t=1757947841" type="image/jpeg" medium="image" fileSize="621313">
        <media:title type="plain">Vial and syringe in row of dominoes</media:title>
      </media:content>
    </item>
    <item>
      <title>Envelope immunogen carrying multiple epitopes for HIV</title>
      <description>
        <![CDATA[Researchers from the California Institute of Technology and collaborating institutions have developed a novel HIV vaccine candidate, a new germline-targeting Env SOSIP trimer called 3nv.2, that is designed to elicit antibodies targeting three key epitopes on the HIV envelope protein.]]>
      </description>
      <guid>http://www.bioworld.com/articles/723480</guid>
      <pubDate>Thu, 21 Aug 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/723480-envelope-immunogen-carrying-multiple-epitopes-for-hiv</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-library/HIV-cell-entry-trancytosis.webp?t=1723562123" type="image/jpeg" medium="image" fileSize="134049">
        <media:title type="plain">Illustration of HIV cell entry</media:title>
      </media:content>
    </item>
    <item>
      <title>ST Pharm divulges new pyrrolopyridine compounds to treat HIV</title>
      <description>
        <![CDATA[ST Pharm Co. Ltd. has synthesized pyrrolopyridine compounds reported to be useful for the treatment of HIV infections.]]>
      </description>
      <guid>http://www.bioworld.com/articles/723377</guid>
      <pubDate>Tue, 19 Aug 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/723377-st-pharm-divulges-new-pyrrolopyridine-compounds-to-treat-hiv</link>
    </item>
    <item>
      <title>Australian researchers identify world-first treatments to prevent HTLV-1 infection</title>
      <description>
        <![CDATA[Around 10 million people globally live with the life-threatening human T-cell lymphotropic virus type-1 (HTLV-1), yet it remains a poorly understood disease that currently has no preventative treatments and no cure. ]]>
      </description>
      <guid>http://www.bioworld.com/articles/722969</guid>
      <pubDate>Tue, 05 Aug 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/722969-australian-researchers-identify-world-first-treatments-to-prevent-htlv-1-infection</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-source/NIH-NIAID-T-Cell-yellow.webp?t=1753887324" type="image/jpeg" medium="image" fileSize="1066027">
        <media:title type="plain">Colorized scanning electron micrograph of a T cell</media:title>
        <media:description type="plain">HTLV-1 is a virus that infects T cells. A new study could lead to the first treatments and potential cure for HTLV-1, which affects 10 million people globally. Credit: National Institute of Allergy and Infectious Diseases. License: CC BY 2.0</media:description>
      </media:content>
    </item>
    <item>
      <title>Australian researchers identify world-first treatments to prevent HTLV-1 infection</title>
      <description>
        <![CDATA[Around 10 million people globally live with the life-threatening human T-cell lymphotropic virus type-1 (HTLV-1), yet it remains a poorly understood disease that currently has no preventative treatments and no cure. That could soon change after Australian researchers discovered that existing HIV drugs can suppress transmission of the HTLV-1 virus in mice.]]>
      </description>
      <guid>http://www.bioworld.com/articles/722871</guid>
      <pubDate>Thu, 31 Jul 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/722871-australian-researchers-identify-world-first-treatments-to-prevent-htlv-1-infection</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-source/NIH-NIAID-T-Cell-yellow.webp?t=1753887324" type="image/jpeg" medium="image" fileSize="1066027">
        <media:title type="plain">Colorized scanning electron micrograph of a T cell</media:title>
        <media:description type="plain">HTLV-1 is a virus that infects T cells. A new study could lead to the first treatments and potential cure for HTLV-1, which affects 10 million people globally. Credit: National Institute of Allergy and Infectious Diseases. License: CC BY 2.0</media:description>
      </media:content>
    </item>
    <item>
      <title>Australian researchers identify world-first treatments to prevent HTLV-1 infection</title>
      <description>
        <![CDATA[Around 10 million people globally live with the life-threatening human T-cell lymphotropic virus type-1 (HTLV-1), yet it remains a poorly understood disease that currently has no preventative treatments and no cure. That could soon change after Australian researchers discovered that existing HIV drugs can suppress transmission of the HTLV-1 virus in mice.]]>
      </description>
      <guid>http://www.bioworld.com/articles/722687</guid>
      <pubDate>Wed, 30 Jul 2025 09:00:00 -0400</pubDate>
      <link>https://www.bioworld.com/articles/722687-australian-researchers-identify-world-first-treatments-to-prevent-htlv-1-infection</link>
      <media:content url="https://www.bioworld.com/ext/resources/BWS/BWS-source/NIH-NIAID-T-Cell-yellow.webp?t=1753887324" type="image/jpeg" medium="image" fileSize="1066027">
        <media:title type="plain">Colorized scanning electron micrograph of a T cell</media:title>
        <media:description type="plain">HTLV-1 is a virus that infects T cells. A new study could lead to the first treatments and potential cure for HTLV-1, which affects 10 million people globally. Credit: National Institute of Allergy and Infectious Diseases. License: CC BY 2.0</media:description>
      </media:content>
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