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THE BIOWORLD BIOME: Our Habitat for All Things Science

According to the WHO's Global tuberculosis report 2017, "TB is the ninth leading cause of death worldwide and the leading cause from a single infectious agent, ranking above HIV/AIDS. In 2016, there were an estimated 1.3 million TB deaths among HIV-negative people."

Angiogenesis for obesity?

A new study by an international team of researchers led by Sweden's Karolinska Institute has for the first time pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat, a key finding that may lead to the discovery of new diabetes and obesity treatments.

Looking where the rare is more common

Mutations in the leucine-rich repeat kinase 2 (LRRK2) have the largest known genetic influence on Parkinson's disease (PD). Now, researchers have reported that mutations in LRRK2 also influenced the risk of Crohn's disease.

The findings of a new study by Swedish and Chinese researchers into a novel photosensitization-based drug-release system could bring about broad changes in the delivery of cancer therapies, with millions of patients worldwide potentially benefitting from this research.

Not dead yet

While the best thing to do with cancer cells is to kill them, the next best thing is to prevent them from growing. Chemotherapies often arrest their growth, forcing tumor cells into senescence.

Try, try, try, try, try, try, try again

Given the state of Alzheimer's disease (AD) drug development, one might wonder whether those engaged in it also suffer from memory loss. Targeting amyloid beta has failed in the clinic, over and over again. But both the failed agents themselves and other amyloid-targeting drugs remain in clinical trials.

Bacterial genomics

HONG KONG – Scientists at The Scripps Research Institute (TSRI) in Jupiter, Fla., have developed a new means of identifying promising new drug candidates from microbial natural products, using information stored in the genomes of the bacteria that produce them.

Why malaria immunity wanes

The discovery of several new key molecules that are involved in severe Plasmodium falciparum malaria is expected to contribute to the development of effective new vaccines and therapeutic drugs against malaria.

SABCS 2017

SAN ANTONIO – Since overexpression of the HER2/Erbb2 receptor was first described as a feature of some breast cancer in 1987, the overexpression has been turned from a negative to a positive predictive factor by the efforts of first academic researchers and then the biopharmaceutical industry.

Cast Your Vote

Should there be restrictions on the use of gene-editing technology?: