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THE BIOWORLD BIOME: Our Habitat for All Things Science

Long-term help for long-term memories

Treating animals with a drug that inhibited the cellular integrated stress response could reverse memory deficits caused by traumatic brain injury (TBI), even if treatment was delayed for several weeks after the injury.

FAI score's FYI

A new way of analyzing computerized tomography (CT) angiography, the standard method for imaging blood vessels to look for potential blockages, could help find future trouble spots before they are causing trouble.

High-flying results

The structure of the human brain's cannabinoid receptor 1 (CB1), which binds to the main psychoactive ingredient in marijuana, delta 9-tetrahydrocannabinol (D9-THC), has been elucidated by Chinese researchers, which could have major implications for drug discovery and development.

AML Smacdown

An international research collaboration has found a means to improve the effect of mimetics of the second mitochondrial-derived activator of caspase (Smac), a novel class of targeted cancer drugs that act by inducing apoptotic cancer cell death and inhibiting pro-survival signaling.

4 + 8 = 2 (years)

Two groups reported that vaccinating melanoma patients with personalized, tumor-specific antigens led to progression-free survival in the majority of patients over roughly two years of follow-up. The results were reported in back-to-back papers in the July 6, 2017, issue of Nature.

Things fall apart

Changes in the 3-D organization of chromosomes in neurons affected the expression of genes that are important for the formation of neuronal connections and that have been implicated in schizophrenia risk, researchers at the Mount Sinai School of Medicine reported in the July 3, 2017, issue of Nature Genetics.

HONG KONG – Scientists at the Riken Brain Science Institute (BSI) have linked low levels of the neurotransmitter serotonin to the symptoms of autism spectrum disorder (ASD) in young mice, suggesting selective serotonin reuptake inhibitors (SSRIs) may have a role in treating autism in humans.

Prenatal repair

A Japanese study has demonstrated a new management approach for fetuses with myelomeningocele (MMC), one of the most severe forms of spina bifida, employing 3-D skin reconstructed using induced pluripotent stem cells (iPSCs) derived from maternal amniotic fluid cells (AFCs).

A(lzheimer's) to Z(ika virus)

BOSTON – The human brain, Jürgen Knoblich told the audience at the 2017 annual meeting of the International Society for Stem Cell Research (ISSCR), consists of "86 billion neurons that have to be born at the right time, move to the right positions and wire up in the right way."

Bench Press


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