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BioWorld - Thursday, May 8, 2025
Home » Topics » Inflammatory, BioWorld Science

Inflammatory, BioWorld Science
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Inflammatory

Chinese scientists divulge new IL-17A inhibitors

May 7, 2025
Researchers at Foshan Ionova Biotherapeutics Co. Ltd., Guangdong Touchstone Translational Research Institute Co. Ltd. and Shenzhen Ionova Life Science Co. Ltd. have synthesized interleukin-17A (IL-17A) inhibitors reported to be useful for the treatment of inflammatory disorders.
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Inflammatory

Quantx divulges new IL-17A/A and IL-17A/F inhibitors

May 5, 2025
Quantx Biosciences US Inc. has synthesized interleukin-17A/A homodimer and/or IL-17A/F heterodimer inhibitors reported to be useful for the treatment of autoimmune and inflammatory diseases.
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Gastrointestinal

Equillium advancing new AhR modulator

May 2, 2025
Equillium Inc. is advancing EQ-504, a potent aryl hydrocarbon receptor (AhR) modulator acquired through the acquisition of Ariagen Inc., a company that was majority owned by Equillium’s largest investor, Decheng Capital.
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Inflammatory

Suzhou Ark Biopharmaceutical patents new PDE4 inhibitors

April 29, 2025
Suzhou Ark Biopharmaceutical Co. Ltd. has disclosed phosphodiesterase PDE4 inhibitors.
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Illustration of scary hand overshadowing crouching girl
Neurology/psychiatric

Psychedelics modulate neuroimmune interactions that control fear

April 28, 2025
By Mar de Miguel
Research of the neuroimmune mechanisms involved in stress-related fear revealed how astrocytes interact with neurons in the amygdala. The study, led by Harvard scientists, also unveiled that this interaction recruited monocytes to the meninges during chronic stress and showed how psychedelic compounds reversed monocyte accumulation in the meninges and reduced fear behavior.
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Antibodies illustration
Inflammatory

Granite Bio emerges from stealth with focus on antibodies for inflammatory, autoimmune and fibrotic conditions

April 25, 2025
Granite Bio AG has emerged from stealth with $100 million in series A and B funding and a focus on developing first-in-class antibodies that target the root causes of a variety of inflammatory, autoimmune and fibrotic conditions.
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Inflammatory

Chengdu Chipscreen Pharmaceutical patents new integrin αvβ1 and αvβ6 antagonists

April 23, 2025
Chengdu Chipscreen Pharmaceutical Ltd. has disclosed integrin αvβ1 and/or αvβ6 antagonists reported to be useful for the treatment of fibrosis.
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Inflammatory

Aclaris gains IND clearance for bispecific anti-TSLP/IL-4R antibody

April 23, 2025
Aclaris Therapeutics Inc. has gained IND clearance from the FDA for ATI-052, a bispecific anti-thymic stromal lymphopoietin (TSLP)/interleukin-4 receptor (IL-4R) monoclonal antibody being developed to treat certain immuno-inflammatory diseases. A phase Ia/Ib trial, including a proof-of-concept portion in an undisclosed indication, will begin in the current quarter.
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Illustration of lymphocytes
Immune

Boehringer Ingelheim and Cue Biopharma agree to advance CUE-501 for autoimmune diseases

April 15, 2025
Boehringer Ingelheim Pharma GmbH & Co KG and Cue Biopharma Inc. have signed a strategic research collaboration and license agreement to develop and commercialize Cue Biopharma’s CUE-501, a differentiated B-cell depletion therapy for autoimmune diseases.
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Antibodies binding to spike proteins on the surface of SARS-CoV-2 virus
Inflammatory

Australian researchers discover new compound to treat long COVID

April 14, 2025
By Tamra Sami
Researchers have developed a new compound that can prevent long COVID symptoms in mice that could lead to a future drug for the debilitating condition in humans. Developed by researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, the world-first study found mice treated with the antiviral compound were protected from long-term brain and lung dysfunction, which are key symptoms of long COVID.
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