Acambis plc, of Cambridge, UK, appointed Randal Chase independent nonexecutive director.

Advancis Pharmaceutical Corp., of Germantown, Md., appointed Joseph Rogus senior vice president of technical operations.

Affimed Therapeutics AG, of Heidelberg, Germany, appointed Rolf Gunther CEO.

AlgoRx Pharmaceuticals Inc., of Secaucus, N.J., appointed Paul Hamelin president and chief operating officer.

American Pharmaceutical Partners Inc., of Schaumburg, Ill., appointed Antonio Pera executive vice president generics business, Margaret Foss vice president quality assurance and quality control, and Bruce Wendel vice president corporate development.

Amgen Inc., of Thousands Oaks, Calif., appointed Jonathan Spear vice president of public policy, and Philip Noguchi director of regulatory affairs.

Anadys Pharmaceuticals Inc., of San Diego, promoted Steve Worland to executive vice president, head of research and development, and Devron Averett to chief scientific officer.

Applied Biosystems Group, of Foster City, Calif., appointed Masahide Habu president of Applied Biosystems Japan Ltd.

Arcturus Bioscience Inc., of Mountain View, Calif., said its CEO and chairman Thomas Baer was appointed consulting professor in the department of applied physics at Stanford University.

Argonaut Technologies Inc., of Redwood City, Calif., appointed Frank Husic to its board.

Ariad Pharmaceuticals Inc., of Cambridge, Mass., appointed Michael Kishbauch to its board.

Array BioPharma Inc., of Boulder, Colo., appointed Ronald Franklin senior director of drug metabolism.

Aryx Therapeutics Inc., of Santa Clara, Calif., appointed Deebie Symmes head of business development.

AspenBio Inc., of Castle Rock, Colo., appointed David Welch to its board.

Aureon Biosciences Corp., of Yonkers, N.Y., appointed Vijay Aggarwal president and CEO.

Bio-key International Inc., of Minneapolis, appointed Kenneth Souza senior vice president and chief technology officer.

BioRexis Pharmaceutical Corp., appointed Tom Amick to its board.

Bone Care International Inc., of Middletown, Wis., appointed Chrys Kokino vice president of marketing.