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Genentech, Curis Win Approval Of Hedgehog Inhibitor Erivedge

By Trista Morrison
Staff Writer

Tuesday, January 31, 2012

Hedgehog has been a household name in biotech circles for decades – both because the Sonic Hedgehog protein owes its whimsical name to a Sega video game character and because scientists have long pursued ways to target the Hedgehog pathway. Now Roche AG's Genentech unit has succeeded – with a little help from Curis Inc. – winning FDA approval of Erivedge (vismodegib) for advanced basal cell carcinoma.

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