The Nuclear Option
Antisense Approach Kills Toxic Myotonic Dystrophy Transcripts
By Anette Breindl
Myotonic dystrophy leads to muscle weakness but also to cardiac arrhythmias, diabetes and cognitive disorders. In fact, Charles Thornton told BioWorld Today, "dystrophy is a bit of misnomer" for the disorder, which he considers closest to a neurodegenerative disease.