AcelRx Pharmaceuticals Inc., of Redwood City, Calif., hired Mark Evashenk as vice president of clinical operations.

Advanced Proteome Therapeutics Corp., of Vancouver, British Columbia, hired Kenneth C. Phillippe as chief financial officer.

Alexza Pharmaceuticals Inc., of Mountain View, Calif., promoted Peter D. Noymer to vice president of product research & development.

Endo Pharmaceuticals Inc., of Chadds Ford, Pa., appointed William P. Montague to the company's board.

MedMira Inc., of Halifax, Nova Scotia, elected James Smith chairman.

Pharmacyclics Inc., of Sunnyvale, Calif., named Robert W. Duggan, the current chairman of the board, CEO.

Pharmaxis, of Sydney, Australia, appointed Howard Fox chief medical officer.

Protein Discovery Inc., of Knoxville, Tenn., hired Jeffrey A. Komatz as chief financial officer.

Savient Pharmaceuticals Inc., of East Brunswick, N.J., named David G. Gionco vice president, chief financial officer and treasurer.

Sinobiomed Inc., of Shanghai, China, made these appointments: Anchie Kuo, president and CEO; Lionel Choong, chief financial officer; Brent Suen, head of strategic development and mergers and acquisitions; and Christopher Metcalf, chairman of the board.

Spectrum Pharmaceuticals Inc., of Irvine, Calif., named Andrew Sandler chief medical officer, Michael Adam senior vice president of pharmaceutical operations, and Amar Singh chief commercial officer.

Trinity Biotech plc, of Dublin, Ireland, appointed James D. Merselis to its board as a nonexecutive director.