Neurocrine Biosciences Inc., of San Diego, completed dosing and preliminary assessment of its initial cohort of patients in an open-label, Phase IIa trial of NBI-98854 for tardive dyskinesia. NBI-98854 is a vesicular monoamine transporter 2 inhibitor (VMAT2). After 12 days of treatment with the drug, test subjects showed improvement in the abnormal hyperkinetic movements caused by tardive dyskinesia.