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Taking a Switch to Cancer Cells

Controlling Means of Production Could Improve Protein Therapies

By Anette Breindl

Monday, October 3, 2011
A frequent challenge for drug developers is how to target drugs – especially cancer drug, which aim to kill their target cells – to the right cell population. But researchers at Johns Hopkins University have turned this problem on its ear: Instead of delivering drugs specifically to cancer cells, they have developed a way to make cancer cells activate prodrugs through use of molecular switches.

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