TOTAL: $336.25M

Company (Symbol)#

Type Of Financing

Number Of Shares, Units Or Warrants (M)

Amount Raised ($M)*

Investors; Placement Agents; Details (Date)@

Abgenix Inc. (ABGX)

Private placement of common stock

1.8S

$75

Abgenix sold 1.8M shares of common stock to selected institutional and other accredited investors at $42 per share; Pacific Growth Equities served as placement agent (11/15)

Avigen Inc. (AVGN)

Private placement of common stock and warrants

ND

$40

Avigen sold an undisclosed amount of common stock and warrants to a group of investors from the United States and Europe; the investor group purchased shares of the common stock in multiple closings at per-share purchase prices equal to the closing prices on the Nasdaq National Market on the respective days of closing; for every five shares purchased, each investor also receives a five-year warrant to purchase one share of common stock at a 25 percent premium to the respective closing price (11/16)

Aviron (AVIR)

Private placement of common stock

0.4MS

$6E

Aviron sold 0.4M shares of its common stock to an undisclosed financial institution; further details ND (11/18)

Axonyx Inc. (OTC BB:AXYX)

Private placement of common stock and warrants

170 units of 0.004S and 0.002W

$4.25

Axonyx sold 170 units at $0.025M to an undisclosed investor; each unit consists of 0.004M shares of restricted common stock and 0.002M five-year warrants, exercisable at $11.00 (11/2)

Cell Therapeutics Inc. (CTIC)

Private placement of convertible preferred stock

ND

$10

Cell Therapeutics sold $10M of its Series A convertible preferred stock, convertible to 4.6M shares of common stock; in connection with the financing, the company issued warrants to the investor group to purchase 1.4M shares of common stock at $2.87 per share; lead investor was Essex Woodlands Health Ventures Fund (11/16)

Digene Corp. (DIGE)

Private placement of common stock

1.5S

$19.5

Digene and certain of its stockholders entered into definitive agreements for the private placement of an aggregate of 1.5M shares of common stock to selected institutional and other accredited investors; 0.9M shares will be sold by the company, and 0.6M shares will be sold by the selling stockholders, all at $13 per share (11/19)

Epoch Pharmaceuticals Inc. (OTC BB:EPPH.OB)

Private placement of stock

ND

$3

Epoch raised $3M in a private financing at a price of $2.50 per share; investors included PE Corp., Bay City Capital, Grace Brothers Ltd. and Hilspen Capital Management; further details ND (11/3)

The Immune Response Corp. (IMNR)

Private placement of common stock

0.8S

$3.1

Immune Response sold 0.8M shares of common stock to an institutional investor at $4 per share, a 6 percent discount to the average of the weighted average trading price of the company's common stock during the 20-trading-day period ended 11/18 (11/23)

Matritech Inc. (NMPS)

Private placement of units

0.9 units of 2S and 1W

$3.6

Undisclosed private investors invested $3.6M in the company through a private placement of 0.9M units at a price of $4 per unit; each unit consisted of two shares of common stock and a warrant to purchase one share of common stock; the warrants are exercisable at $2.20 per share for a period of two years and are callable by Matritech if certain common stock price levels are reached during the two-year period (11/18)

Maxim Pharmaceuticals Inc. (AMEX:MMP)

Private placement of convertible preferred stock

ND

$20.6

Maxim placed $20.6M of convertible preferred stock with a group of existing shareholders and new investors based in the U.S. and Europe; the preferred stock is convertible into shares of common stock at a fixed price of $8.90 per share, based on the average closing bid prices for the five days prior to completion of the placement; the preferred stock may be converted into a total of 2.3M shares of common stock (11/2)

NeoTherapeutics Inc. (NEOT)

Private placement of common stock

0.8S

$10

NeoTherapeutics sold 0.8M shares of common stock to two institutional investors at $11.83 per share; in addition, the investors received five-year warrants to purchase 0.13M shares of common stock at an exercise price of $14.24 per share, and additional adjustment warrants to purchase additional shares of common stock at two reset dates, four and six months subsequent to the closing (11/19)

Neurobiological Technologies Inc. (OTC BB:NTII)

Private placement of securities

Units of 5S stock and 1W

$4.2

Neurobiological raised $4.2M in gross proceeds from a private placement of its securities at $4 per unit; each unit consisted of five shares of common stock and a five-year warrant to purchase two shares of common stock exercisable at $1.75 per share; placement agent was AmeriCal Securities Inc.; existing and new investors included Paramount Capital Inc., Clarion Capital Corp. and Active Site Partners (11/11)

Nexell Therapeutics Inc. (NEXL)

Private placement of convertible preferred stock

0.063S

$63

Nexell raised $63M in a private placement of Series B preferred stock, convertible into common stock at $2.75 per share; Lehman Brothers acted as placement agent; investors included John Hancock Mutual Life Insurance Co., Metropolitan Life Insurance Co. and Massachusetts Mutual Life Insurance Co. (11/29)

Nymox Pharmaceutical Corp. (NYMX)

Private placement of common stock

ND

$12

Nymox raised $12M in a private placement of common stock to institutional investors; Ladenburg Thalmann & Co. acted as placement agent (11/12)

Procyon Biopharma Inc. (Canada; ASE:PBP)

Private placement of common stock

12S

$2

Procyon completed the second phase of a private financing, the first phase of which was completed in October; the company issued 12M shares of common stock at $0.25 per share to European and other investors, and to T2C2 and Innovatech du Grand Montreal, Quebec-based venture capital firms (11/22)

Notes:

@ The dates listed indicate the issue dates of press releases, and are not necessarily the dates on which stated events took place.

* Conversion rate of C$1 3D US$0.68; ND 3D Information not disclosed.

# Unless otherwise indicated, the stock symbols listed are on the Nasdaq Market.

AMEX 3D American Stock Exchange, ASE 3D Alberta Stock Exchange, OTC BB 3D Over-the-Counter Bulletin Board