I. COMMENCED TRADING IN October

Company (Symbol)#

Date Filed

Date Comm.

Shares/Units (M)

Price

Shares Out  (M)@

Lead, Other Underwriters

Gross (US$M)

Post-Offering Market Cap (M)%


INITIAL OFFERINGS

 

Pacific Biosciences Inc. (PACB)1

8/16

10/27

12.5S

$16

50. 1

J.P. Morgan Securities
Morgan Stanley (co-lead)
Deutsche Bank Securities
Piper Jaffray & Co.

$200

$801.6

 

Total: $200M

Number of IPOs in October: 1
Average value of October IPOs: $200M
Number of IPOs in 2010: 13
Total raised in IPOs in 2010: $911 .06M
Average value of IPOs in 2010: $70. 1M

 

Company (Symbol)#

Date Filed

Date Comm.

Shares/Units (M)

Price

Shares Out (M)@

Lead, Other Underwriters

Gross (US$M)

Post-Offering Market Cap (M)%


FOLLOW-ON OFFERINGS

 

Aegerion Pharmaceuticals Inc. (AEGR)2

8/10

10/25

5S

$9.50

16.9

Leerink Swann
Lazard Capital (co-lead)
Needham & Co.
Canaccord Genuity
Collins Stewart

$47.5

$160.55

 

Anadys Pharmaceuticals Inc. (ANDS)3

4/23/09

10/15

13.9S

$1 .80

57.1

Lazard Capital Markets

$25

$102.78

 

Ariad Pharmaceuticals Inc. (ARIA)4

1/21

10/25

16S

$3.70

126.9

Jefferies & Co. Inc.
Oppenheimer & Co. (co-lead)

$59.2

$469.53

 

Celgene Corp. (CELG)5

10/4

10/5

Notes

N/A

N/A

Citigroup Global Markets
J.P. Morgan Sec. (Co-Lead)Morgan Stanley (Co-Lead)

$1.25B

N/A

 

Chelsea Therapeutics International Inc. (CHTP)6

9/30

10/4

8.21S

$4.90

49.07

Deutsche Bank Sec.
Needham & Co. LLC

$40.23

$240.4

 

Cubist Pharmaceuticals Inc. (CBST)7

10/19

10/19

Convertible notes

NA

N/A

Goldman Sachs & Co.
Morgan Stanley (co-lead)
Citigroup Global Markets
RBC Capital Markets

$450

N/A

 

Cytori Therapeutics Inc. (CYTX)8

2/11/09

10/8

4.6S

$4.50

50.5

Jefferies & Co. Inc.

$20.7

$227.25

 

Dynavax Technologies Corp. (DVAX)9

10/6

10/28

26.45S

$1.70

114.75

Jefferies & Co.
Wedbush PacGrow
Cowen and Co.

$44.97

$195.1

 

GTx Inc. (GTXI)10

1/17/08

10/27

14.3S

$2.80

50.7

Lazard Capital Markets

$40

$141.96

 

OncoGenex Pharmaceuticals Inc. (OGXI)

7/17/09

10/19

3.2U

$15.75

9.7

Stifel Nicolaus Weisel
Needham & Co.
Rodman & Renshaw
WedBush PacGrow

$50

$152.8

 

Regeneron Pharmaceuticals Inc. (REGN)11

10/6

10/8

6.325S

$27.69

86.33

Citibank Global Markets

$175.14

$2,390.5

 

Sunesis Pharmaceuticals Inc. (SNSS)

5/20

10/4

44.1U

$0.35

265.3

Cowen and Co. LLC
ThinkEquity LLC

$15.5

$92.9

 

Total: $2,218.24M

Number of follow-on offerings in October: 12
Average value of October follow-ons: $184.9M
Number of follow-on offerings in 2010: 59
Total raised in follow-ons in 2010: $4,927,91M
Average value of follow-ons in 2010: $83.5M


Notes:

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

@ This column reflects the shares outstanding following the offering, when disclosed.

% Market capitalization is calculated based on the offering price.

Currency conversions are based on exchange rates at the time of the deal.

1 Pacific BioSciences' overallotment option: 1.875M shares.

2 Aegerion's overallotment option: 750,000 shares.

3 Anadys' overallotment option: 2. 1M shares.

4 Ariad's overallotment option: 2.4M shares.

5 Celgene priced $500M in 2.45% senior notes due October 2015, $500M in 3.95% senior notes due October 2020 and $250M in 5.7% senior notes due October 2040.

6 Includes Chelsea's overallotment option: 1 .07M shares.

7 Includes Cubist's overallotment option: $50M in convertible notes.

8 Includes Cytori's overallotment option: 600,000 shares.

9 Includes Dynavax's overallotment option: 3.45M shares.

10 GTX's overallotment option: 2. 1M shares.

11 Includes Regeneron's overallotment option: 825,000 shares.

 

II. FILED AND PENDING

 

Company (Symbol)#

Date Filed

Shares/Units (M)

Price

Shares Out

Lead, Other Underwriters (M)@

Gross (US$M)


INITIAL OFFERINGS

 

Aegerion Pharmaceuticals Inc. (AEGR)

8/10/10

5S

$9.50

N/A

Leerink Swann
Lazard Capital Markets (co-lead)
Needham & Co. LLC
Canaccord Genuity

$86.25

 

Aldagen Inc. (ALDH)

10/29/09

Units

N/A

N/A

Boenning & Scattergood
Ladenburg Thalmann (co-lead)
National Securities Corp.

$46

 

Anacor Pharmaceuticals Inc. (ANAC)

9/10/10

N/A

N/A

N/A

Citibank
Deutsche Bank Securities (co-lead)
Cowen and Co.
Wedbush PacGrow Life Sciences

$86.25

 

BG Medicine Inc. (BGMD)

1/29/10

N/A

N/A

N/A

Jefferies & Co.
UBS Investment Bank (co-lead)
Cowen & Co.
Baird

$86.25

 

BioLineRx Ltd. (BLRX)

9/24/10

N/A

N/A

N/A

JMP Securities
Oppenheimer & Co.

$40.25

 

Broadvector Ltd. (Australia; ASX)

9/8/10

42.5S

20 cents

N/A

N/A

$8.5

 

Complete Genomics Inc. (GNOM)

7/30/10

N/A

N/A

N/A

UBS Investment Bank
Jefferies & Co. (co-lead)
Baird
Cowen & Co.

$86.25

 

Endocyte Inc. (ECYT)

8/17/10

N/A

N/A

N/A

RBC Capital Markets
Leerink Swann (co-lead)
Wedbush PacGrow Life Sciences
Robert W. Baird

$86.25

 

Horizon Pharma Inc. (HZNP)

8/3/10

N/A

N/A

N/A

Jefferies & Co.
Piper Jaffray (co-lead)
JMP Securities
Lazard Capital Markets

$86.25

 

Ikaria Inc. (IKAR)

5/13/10

N/A

N/A

N/A

Goldman Sachs
Morgan Stanley (co-lead)
Credit Suisse
Lazard Capital
Cowen & Co.
Wedbush PacGrow

$200

 

Med BioGene Inc. (Canada; MGBI)1

12/28/09

N/A

N/A

N/A

Rodman & Renshaw LLC

$24

 

Prometheus Laboratories Inc. or Prometheus RxDx Corp. (RXDX)

12/19/07

N/A

N/A

N/A

Goldman Sachs & Co.
Credit Suisse (co-lead)
SunTrust Robinson Humphrey
Cowen & Co.
WedBush PacGrow Life Sci.

$151.3

 

Quark Pharmaceuticals Inc. (TASE)2

9/28/10

N/A

N/A

N/A

N/A

$20

 

Zogenix Inc. (ZGNX)

9/8/10

N/A

N/A

N/A

Wells Fargo Securities LLC
Leerink Swann LLC (co-lead)
Oppenheimer & Co.
Stifel Nicolaus Weisel

$90


Notes: # Unless otherwise indicated, shares are traded on the Nasdaq exchange.

CDNX = Canadian Venture Exchange.

General shelf registration statements are not included until action is taken on the filing.

* Stock symbols for companies seeking to complete IPOs are proposed.

@ This column reflects the shares outstanding following the offering, when disclosed.

N/A = Not available, applicable or reported.

The value of all offerings is based on either the midpoint of the price range listed in the company's SEC filing or the most recent closing stock price before the offering was announced. In some cases, the company has not disclosed the number of shares to be offered or a price range. Then, the value is the maximum aggregate offering price listed in the SEC filing.

1 Med BioGene secured Rodman & Renshaw for an IPO in the U.S.