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Good Fences and All That

Too-Close Neighbors Spell Trouble in Ovarian Cancer

By Anette Breindl

Wednesday, September 21, 2011
Bcr-Abl is the root cause of most cases of chronic myelogenous leukemia (CML) and the target of Gleevec (imatinib, Novartis AG) and several second-generation agents. It was the first gene fusion that was identified as a cause of cancer, and its success story continues to be a motivator for researchers looking for similar fusions.

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