I. COMMENCED TRADING IN SEPTEMBER
Company (Symbol)# Date Filed Date Comm. Shares/ Units (M) Price Shares Out (M)@ Lead, Other Underwriters Gross (US$M) Post-Offering Market Cap (M)%

INITIAL OFFERINGS
GNI Ltd. (Japan; TSE:2160)1 9/4 9/4 10S 90 yen N/A N/A 900 yen ($7.7) N/A
Total: $7.7M
Number of IPOs in September: 1
Average value of September IPOs: $7.7
Number of IPOs in 2007: 32
Total raised in IPOs in 2007: $1,570.9M
Average value of IPOs in 2007: $49.09M
FOLLOW-ON OFFERINGS
Company (Symbol)# Date Filed Date Comm. Shares/ Units (M) Price Shares Out (M)@ Lead, Other Underwriters Gross (M) Post-Offering Market Cap (M)%

Exelixis Inc. (EXEL)2 9/10/07 9/13/07 7S $10.30 104.3 Goldman, Sachs & Co. $72.1 $1,074.29
InterMune Inc. (ITMN)3 9/19/07 9/21/07 4.525S $19.50 39.2 Goldman, Sachs & Co.
Deutsche Bank (co-lead)
CIBC World Markets
$88.2 $764.4
Progenics Pharmaceuticals Inc. (PGNX)4 9/20/07 9/20/07 2.6S $23.15 N/A UBS Investment Bank
CIBC World Markets
Morgan Stanley & Co.
$57 N/A
Total: $217.3M
Number of follow-on offerings in September: 3
Average value of September follow-ons: $72.4M
Number of follow-on offerings in 2007: 42
Total raised in follow-ons in 2007: $2,698M
Average value of follow-ons in 2007: $64.24M

Notes:
# Unless otherwise indicated, shares are traded on the Nasdaq exchange.
@ This column reflects the shares outstanding following the offering, when disclosed.
% Market capitalization is calculated based on the offering price.
Currency conversions are based on exchange rates at the time of the deal.
TSE = Tokyo Stock Exchange

1 GNI went public on the Tokyo Stock Exchange.
2 Exelixis' overallotment option: 1.1M shares.
3 Includes InterMune's overallotment option: 525,000 shares
4 Progenics' overallotment option: 390,000 shares.
II. FILED AND PENDING
Company (Symbol/Proposed Symbol)#* Date Filed Shares/Units (M) Price Range Shares Out (M)@ Lead, Other Underwriters Value (M)
INITIAL OFFERINGS
Anacor Pharmaceuticals Inc. (ANAC) 8/31/07 N/A N/A N/A Morgan Stanley & Co. Inc.
Cowen & Co. LLC (co-lead)
Pacific Growth Equities LLC
Needham & Co. LLC
$57.5
Archemix Corp.
(ARCH)
7/25/07 N/A N/A N/A Banc of America Securities
Bear, Stearns & Co. Inc.
Cowen and Co.
$69
ARYx Therapeutics Inc. (ARYX) 8/31/07 N/A N/A N/A Morgan Stanley & Co. Inc.
CIBC World Markets Corp.
Jefferies & Co. Inc.
Leerink Swann & Co. Inc.
$86.25
Bioheart Inc. (BHRT)1 2/13/07 3.575 $14-$16 16.9 BMO Capital Markets Corp.
Janney Montgomery Scott (co-lead)
Merriman Curhan Ford & Co.
$53.6
Biolex Inc. (BLEX) 8/14/07 N/A N/A N/A Lehman Brothers Inc.Deutsche
Bank Securities (co-lead)
Leerink Swann & Co. Inc.
$70
Elixir Pharmaceuticals Inc. (ELXR) 9/24/07 N/A N/A 143.5 Credit Suisse Securities LLC
Pacific Growth Equities
Leerink Swann LLC
$86
Genoptix Inc. (GXDX) 8/1/07 N/A N/A N/A Lehman Brothers
Banc of America Sec. Cowen and Co.
$86.25
Insys Therapeutics Inc. (INRX) 8/20/07 N/A N/A N/A Banc of America Securities
UBS Investment Bank (co-lead)
JMP Securities
Natixis Bleichroeder
$86.25
Light Sciences Oncology Inc.(LSON) 4/21/06 5.25S $14-$16 18.5 Cowen & Co.
Wachovia Securities (co-lead) Jefferies & Co.

Thomas Weisel Partners

$78.75
MAP Pharmaceuticals Inc. (MAPP) 6/18/07 5S $14-$16 19.3 Merrill Lynch & Co.
Morgan Stanley (co-lead)
Deutsche Bank Sec.
$75
Merrion Pharmaceuticals Ltd. (MERR)2 4/3/07 4S $10-$12 15 Punk, Ziegel & Co.
Goodbody Stockbrokers Stanford Group Co.
$44
MonoSol Rx Inc.

(MSRX)

5/14/07 4S $16-$18 N/A Cowen and Co.
CIBC World Markets Susquehanna Financial
$68
Nanoshere Inc.

(NSPH)

8/13/07 N/A N/A N/A Credit Suisse
Piper Jaffray
Leerink Swann & Co.
Allen & Co. LLC
$100
NovaBay Pharmaceuticals Inc. (AMEX:NBY; TSX:NBY)3 2/15/07 5S $4-$6 21.1 Dundee Securities
Desjardins Sec. International
Blackmont Capital

Dawson James Sec.

$25
Peplin Inc. (PLIN)4 8/10/07 N/A N/A N/A Merrill Lynch & Co.
Cowen & Co. LLC Thomas Weisel Partners
Leerink Swann & Co.
Merrill Lynch International

Wilson HTM

$75
Precision Therapeutics Inc. 8/24/07 N/A N/A N/A JP Morgan
Piper Jaffray (co-lead)
JMP Securities
$80.5
Reliant Pharmaceuticals Inc. (NYSE:RRX) 8/10/07 N/A N/A N/A Goldman, Sachs & Co.
Merrill Lynch & Co. (co-lead)
Bank of America Securities
Lazard Capital Markets
$400
Talecris Biotheraeutics Holdings Corp. (TLCR) 7/30/07 N/A N/A N/A Morgan Stanley
Goldman Sachs & Co.
J.P. Morgan
$1B
Targanta Therapeutics Corp. (TARG) 5/14/07 5.8S $12-$14 21 Credit Suisse Securities
Cowen and Co.
Lazard Capital Markets
Leerink Swann and Co.
$75.4
FOLLOW-ON OFFERINGS
Ambrilia Biopharma Inc. (Canada; TSX:AMB) 9/18/07 N/A N/A N/A Canaccord Capital
Dundee Securities
Loewen, Ondaatje, McCutcheon
$15
Bionovo Inc. (BNVI) 9/24/07 11.4S $3.99 77.4 BMO Capital Markets
Canaccord Adams (co-lead)
Merriman Curhan Ford & Co.
$45.5
Bioxel Pharma Inc. (Canada; CDNX:BIP)5 7/9/07 N/A N/A N/A Paradigm Capital
Laurentian Bank Sec.
N/A
Chemokine Therapeutics Corp. (Canada; TSX:CTI; OTC BB: CHKT) 5/30/07 N/A N/A N/A GMP Securities $25
Neurobiological Technologies Inc. (NTII) 8/13/07 N/A N/A N/A Merriman Curhan Ford $75
Neurochem Inc. (NRMX) 1/18/07 N/A N/A N/A N/A $102
WITHDRAWN AND POSTPONED
Company (Symbol/Proposed Symbol)#* Date Filed/ Date Pulled Shares/ Units (M) Price Range Shares Out (M)@ Lead, Other Underwriters Value (M)

Adnexus Therapeutics Inc. (ADNX)6 8/22/07

9/24/07

N/A N/A N/A Lehman Brothers
UBS Securities (co-lead)
Cowen & Co.
Lazard Freres & Co. LLC
$86

Notes:

# Unless otherwise indicated, shares are traded on the Nasdaq exchange; general shelf registration statements are not included until action is taken on the filing.
* Stock symbols for companies seeking to complete IPOs are proposed.
@ This column reflects the shares outstanding following the offering, when disclosed. The value of all offerings is based on either the midpoint of the price range listed in the company's SEC filing or the most recent closing stock price before the offering was announced. In some cases, the company has not disclosed the number of shares to be offered or a price range. Then, the value is the maximum aggregate offering price listed in the SEC filing.
N/A = Not available, applicable or reported.
AMEX = American Stock Exchange; CDNX = Canadian Venture Exchange; NYSE = New York Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSX = Toronto Stock Exchange.

1 Bioheart's overallotment option: 536,250 shares.
2 Merrion plans to list American depositary shares on Nasdaq and ordinary shares in a secondary listing on the Irish Enterprise Exchange, both under the ticker "MERR."
3 NovaBay is seeking a dual listing on the American and Toronto stock exchanges.
4 Peplin Ltd., of Australia, established the U.S. subsidiary to facilitate an IPO.
5 Bioxel filed for a Canadian offering of units consisting of one common share and one-half of a common share purchase warrant.
6 Adnexus pulled its IPO because Bristol-Myers Squibb Co. is acquiring it.